Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-01 | Texas A&M-Kingsville | 72 | 76 | Texas A&M (140) | Final | W | 4 |
| 2 | 2021-11-10 | North Florida (301) | 46 | 64 | Texas A&M (140) | Final | W | 18 |
| 3 | 2021-11-12 | Abilene Christian (245) | 80 | 81 | Texas A&M (39) | Final/2OT | W | 1 |
| 4 | 2021-11-14 | Texas A&M-Corpus Christi (208) | 65 | 86 | Texas A&M (39) | Final | W | 21 |
| 5 | 2021-11-17 | Houston Baptist (235) | 39 | 73 | Texas A&M (36) | Final | W | 34 |
| 6 | 2021-11-22 | Texas A&M (39) | 58 | 69 | Wisconsin (24) | Final | L | -11 |
| 7 | 2021-11-23 | Texas A&M (38) | 57 | 50 | Butler (118) | Final | W | 7 |
| 8 | 2021-11-24 | Texas A&M (39) | 73 | 67 | Notre Dame (101) | Final | W | 6 |
| 9 | 2021-11-30 | New Orleans (238) | 65 | 85 | Texas A&M (42) | Final | W | 20 |
| 10 | 2021-12-11 | TCU (32) | 68 | 64 | Texas A&M (39) | Final | L | -4 |
| 11 | 2021-12-14 | Tulane (167) | 0 | 0 | Texas A&M (39) | Cancelled | - | - |
| 12 | 2021-12-18 | Texas A&M (39) | 83 | 73 | Oregon State (144) | Final | W | 10 |
| 13 | 2021-12-21 | Northwestern State (315) | 61 | 80 | Texas A&M (39) | Final | W | 19 |
| 14 | 2021-12-27 | Dallas Christian | 52 | 102 | Texas A&M (39) | Final | W | 50 |
| 15 | 2021-12-29 | Central Arkansas (143) | 59 | 85 | Texas A&M (39) | Final | W | 26 |
| 16 | 2022-01-04 | Texas A&M (39) | 81 | 79 | Georgia (35) | Final | W | 2 |
| 17 | 2022-01-08 | Arkansas (16) | 81 | 86 | Texas A&M (39) | Final | W | 5 |
| 18 | 2022-01-11 | Ole Miss (79) | 51 | 67 | Texas A&M (39) | Final | W | 16 |
| 19 | 2022-01-15 | Texas A&M (39) | 67 | 64 | Missouri (51) | Final | W | 3 |
| 20 | 2022-01-19 | Kentucky (26) | 64 | 58 | Texas A&M (39) | Final | L | -6 |
| 21 | 2022-01-22 | Texas A&M (39) | 73 | 76 | Arkansas (16) | Final/OT | L | -3 |
| 22 | 2022-01-26 | Texas A&M (45) | 64 | 70 | LSU (8) | Final | L | -6 |
| 23 | 2022-01-29 | South Carolina (110) | 74 | 63 | Texas A&M (39) | Final | L | -11 |
| 24 | 2022-02-01 | Texas A&M (47) | 80 | 90 | Tennessee (19) | Final | L | -10 |
| 25 | 2022-02-05 | Missouri (51) | 70 | 66 | Texas A&M (39) | Final | L | -4 |
| 26 | 2022-02-08 | LSU (18) | 76 | 68 | Texas A&M (65) | Final | L | -8 |
| 27 | 2022-02-12 | Texas A&M (39) | 58 | 75 | Auburn (37) | Final | L | -17 |
| 28 | 2022-02-15 | Florida (47) | 55 | 56 | Texas A&M (70) | Final | W | 1 |
| 29 | 2022-02-19 | Texas A&M (70) | 67 | 72 | Vanderbilt (79) | Final | L | -5 |
| 30 | 2022-02-22 | Georgia (210) | 77 | 91 | Texas A&M (72) | Final | W | 14 |
| 31 | 2022-02-26 | Texas A&M (72) | 76 | 66 | Ole Miss (101) | Final | W | 10 |
| 32 | 2022-03-02 | Texas A&M (62) | 87 | 71 | Alabama (21) | Final | W | 16 |
| 33 | 2022-03-05 | Mississippi State (57) | 64 | 67 | Texas A&M (62) | Final | W | 3 |
| 34 | 2022-03-10 | Florida (50) | 80 | 83 | Texas A&M (53) | Final | W | 3 |
| 35 | 2022-03-11 | Texas A&M (53) | 67 | 62 | Auburn (4) | Final | W | 5 |
| 36 | 2022-03-12 | Texas A&M (53) | 82 | 64 | Arkansas (16) | Final | W | 18 |
| 37 | 2022-03-13 | Texas A&M (38) | 50 | 65 | Tennessee (5) | Final | L | -15 |
| 38 | 2022-03-15 | Alcorn State (261) | 62 | 74 | Texas A&M (38) | Final | W | 12 |
| 39 | 2022-03-19 | Oregon (75) | 60 | 75 | Texas A&M (38) | Final | W | 15 |
| 40 | 2022-03-23 | Wake Forest (48) | 52 | 67 | Texas A&M (38) | Final | W | 15 |
| 41 | 2022-03-29 | Washington State (69) | 56 | 72 | Texas A&M (38) | Final | W | 16 |
| 42 | 2022-03-31 | Xavier (42) | 73 | 72 | Texas A&M (38) | Final | L | -1 |