Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Texas Southern (171) | 66 | 83 | Oregon (28) | Final | W | 17 |
| 2 | 2021-11-12 | SMU (45) | 63 | 86 | Oregon (102) | Final | W | 23 |
| 3 | 2021-11-16 | BYU (52) | 81 | 49 | Oregon (32) | Final | L | -32 |
| 4 | 2021-11-22 | Oregon (102) | 73 | 49 | Chaminade | Final | W | 24 |
| 5 | 2021-11-23 | Oregon (110) | 50 | 62 | Saint Mary's (83) | Final | L | -12 |
| 6 | 2021-11-24 | Houston (5) | 78 | 49 | Oregon (102) | Final | L | -29 |
| 7 | 2021-11-29 | Montana (176) | 47 | 87 | Oregon (175) | Final | W | 40 |
| 8 | 2021-12-01 | UC-Riverside (292) | 65 | 71 | Oregon (102) | Final | W | 6 |
| 9 | 2021-12-05 | Arizona State (220) | 69 | 67 | Oregon (175) | Final (OT) | L | -2 |
| 10 | 2021-12-12 | Oregon (102) | 69 | 72 | Stanford (60) | Final | L | -3 |
| 11 | 2021-12-15 | Portland (210) | 71 | 96 | Oregon (102) | Final | W | 25 |
| 12 | 2021-12-18 | Baylor (58) | 78 | 70 | Oregon (102) | Final | L | -8 |
| 13 | 2021-12-21 | Pepperdine (283) | 59 | 68 | Oregon (102) | Final | W | 9 |
| 14 | 2021-12-30 | Colorado (73) | 0 | 0 | Oregon (102) | Postponed | - | - |
| 15 | 2022-01-01 | Utah (130) | 66 | 79 | Oregon (102) | Final | W | 13 |
| 16 | 2022-01-03 | Colorado (73) | 0 | 0 | Oregon (102) | Postponed | - | - |
| 17 | 2022-01-08 | Oregon (102) | 0 | 0 | Oregon State (144) | Postponed | - | - |
| 18 | 2022-01-10 | Oregon (96) | 78 | 76 | Oregon State (215) | Final | W | 2 |
| 19 | 2022-01-13 | Oregon (102) | 84 | 81 | UCLA (30) | Final/OT | W | 3 |
| 20 | 2022-01-15 | Oregon (102) | 79 | 69 | USC (71) | Final | W | 10 |
| 21 | 2022-01-20 | Washington State (179) | 0 | 0 | Oregon (102) | Postponed | - | - |
| 22 | 2022-01-23 | Washington (121) | 56 | 84 | Oregon (53) | Final | W | 28 |
| 23 | 2022-01-25 | Colorado (67) | 82 | 78 | Oregon (53) | Final | L | -4 |
| 24 | 2022-01-29 | Oregon State (144) | 56 | 78 | Oregon (102) | Final | W | 22 |
| 25 | 2022-02-03 | Oregon (102) | 66 | 51 | Colorado (73) | Final | W | 15 |
| 26 | 2022-02-05 | Oregon (102) | 80 | 77 | Utah (130) | Final | W | 3 |
| 27 | 2022-02-10 | Stanford (60) | 60 | 68 | Oregon (102) | Final | W | 8 |
| 28 | 2022-02-12 | California (65) | 78 | 64 | Oregon (102) | Final | L | -14 |
| 29 | 2022-02-14 | Washington State (179) | 59 | 62 | Oregon (102) | Final | W | 3 |
| 30 | 2022-02-17 | Oregon (102) | 57 | 81 | Arizona State (61) | Final | L | -24 |
| 31 | 2022-02-19 | Oregon (58) | 81 | 84 | Arizona (1) | Final | L | -3 |
| 32 | 2022-02-24 | UCLA (12) | 63 | 68 | Oregon (59) | Final | W | 5 |
| 33 | 2022-02-26 | USC (18) | 70 | 69 | Oregon (59) | Final | L | -1 |
| 34 | 2022-03-03 | Oregon (56) | 67 | 78 | Washington (107) | Final | L | -11 |
| 35 | 2022-03-05 | Oregon (56) | 74 | 94 | Washington State (77) | Final | L | -20 |
| 36 | 2022-03-09 | Oregon State (275) | 72 | 86 | Oregon (72) | Final | W | 14 |
| 37 | 2022-03-10 | Oregon (72) | 69 | 80 | Colorado (58) | Final | L | -11 |
| 38 | 2022-03-15 | Oregon (75) | 83 | 72 | Utah State (81) | Final | W | 11 |
| 39 | 2022-03-19 | Oregon (75) | 60 | 75 | Texas A&M (38) | Final | L | -15 |