Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-10-29 | Wisonsin-Whitewater | 50 | 76 | Wisconsin (30) | Final | W | 26 |
| 2 | 2021-11-09 | St. Francis (NY) (229) | 58 | 81 | Wisconsin (30) | Final | W | 23 |
| 3 | 2021-11-12 | Green Bay (206) | 34 | 72 | Wisconsin (24) | Final | W | 38 |
| 4 | 2021-11-15 | Providence (51) | 63 | 58 | Wisconsin (62) | Final | L | -5 |
| 5 | 2021-11-22 | Texas A&M (39) | 58 | 69 | Wisconsin (24) | Final | W | 11 |
| 6 | 2021-11-23 | Wisconsin (111) | 65 | 63 | Houston (20) | Final | W | 2 |
| 7 | 2021-11-24 | Wisconsin (24) | 61 | 55 | Saint Mary's (33) | Final | W | 6 |
| 8 | 2021-12-01 | Wisconsin (24) | 70 | 66 | Georgia Tech (158) | Final | W | 4 |
| 9 | 2021-12-04 | Marquette (106) | 76 | 89 | Wisconsin (24) | Final | W | 13 |
| 10 | 2021-12-08 | Indiana (43) | 59 | 64 | Wisconsin (9) | Final | W | 5 |
| 11 | 2021-12-11 | Wisconsin (24) | 55 | 73 | Ohio State (34) | Final | L | -18 |
| 12 | 2021-12-15 | Nicholls State (250) | 68 | 71 | Wisconsin (24) | Final | W | 3 |
| 13 | 2021-12-23 | George Mason (86) | 0 | 0 | Wisconsin (24) | Cancelled | - | - |
| 14 | 2021-12-23 | Morgan State | 0 | 0 | Wisconsin | Cancelled | - | - |
| 15 | 2021-12-29 | Illinois State (94) | 85 | 89 | Wisconsin (24) | Final | W | 4 |
| 16 | 2022-01-03 | Wisconsin (24) | 74 | 69 | Purdue (8) | Final | W | 5 |
| 17 | 2022-01-06 | Iowa (28) | 78 | 87 | Wisconsin (24) | Final | W | 9 |
| 18 | 2022-01-09 | Wisconsin (9) | 70 | 69 | Maryland (98) | Final | W | 1 |
| 19 | 2022-01-13 | Ohio State (34) | 68 | 78 | Wisconsin (24) | Final | W | 10 |
| 20 | 2022-01-18 | Wisconsin (24) | 82 | 76 | Northwestern (75) | Final | W | 6 |
| 21 | 2022-01-21 | Michigan State (13) | 86 | 74 | Wisconsin (7) | Final | L | -12 |
| 22 | 2022-01-27 | Wisconsin (24) | 73 | 65 | Nebraska (13) | Final | W | 8 |
| 23 | 2022-01-30 | Minnesota (64) | 60 | 66 | Wisconsin (9) | Final | W | 6 |
| 24 | 2022-02-02 | Wisconsin (9) | 67 | 80 | Illinois (21) | Final | L | -13 |
| 25 | 2022-02-05 | Penn State (129) | 49 | 51 | Wisconsin (24) | Final | W | 2 |
| 26 | 2022-02-08 | Wisconsin (12) | 70 | 62 | Michigan State (17) | Final | W | 8 |
| 27 | 2022-02-12 | Rutgers (112) | 73 | 65 | Wisconsin (24) | Final | L | -8 |
| 28 | 2022-02-15 | Wisconsin (15) | 74 | 69 | Indiana (45) | Final | W | 5 |
| 29 | 2022-02-20 | Michigan (44) | 63 | 77 | Wisconsin (15) | Final | W | 14 |
| 30 | 2022-02-23 | Wisconsin (15) | 68 | 67 | Minnesota (84) | Final | W | 1 |
| 31 | 2022-02-26 | Wisconsin (15) | 66 | 61 | Rutgers (69) | Final | W | 5 |
| 32 | 2022-03-01 | Purdue (9) | 67 | 70 | Wisconsin (13) | Final | W | 3 |
| 33 | 2022-03-06 | Nebraska (149) | 74 | 73 | Wisconsin (15) | Final | L | -1 |
| 34 | 2022-03-11 | Michigan State (34) | 69 | 63 | Wisconsin (15) | Final | L | -6 |
| 35 | 2022-03-18 | Colgate (157) | 60 | 67 | Wisconsin (15) | Final | W | 7 |
| 36 | 2022-03-20 | Iowa State (39) | 54 | 49 | Wisconsin (15) | Final | L | -5 |