Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | St. Mary's (MD) | 55 | 118 | Morgan State (215) | Final | W | 63 |
| 2 | 2021-11-11 | Penn State-Greater Allegheny | 71 | 126 | Morgan State (215) | Final | W | 55 |
| 3 | 2021-11-14 | Morgan State (337) | 53 | 90 | George Mason (86) | Final | L | -37 |
| 4 | 2021-11-18 | Morgan State (180) | 80 | 93 | Seattle (149) | Final | L | -13 |
| 5 | 2021-11-20 | Morgan State (337) | 63 | 74 | Portland (210) | Final | L | -11 |
| 6 | 2021-11-22 | Morgan State (337) | 67 | 83 | San Francisco (122) | Final | L | -16 |
| 7 | 2021-11-22 | Morgan State | 0 | 0 | San Francisco State | Cancelled | - | - |
| 8 | 2021-11-28 | Grambling (298) | 74 | 59 | Morgan State (284) | Final | L | -15 |
| 9 | 2021-11-29 | Morgan State (284) | 60 | 47 | Hampton (320) | Final | W | 13 |
| 10 | 2021-12-06 | Millersville | 71 | 77 | Morgan State (291) | Final | W | 6 |
| 11 | 2021-12-11 | Morgan State (337) | 55 | 94 | Longwood (269) | Final | L | -39 |
| 12 | 2021-12-18 | Morgan State (337) | 60 | 74 | Mount St Mary's (257) | Final | L | -14 |
| 13 | 2021-12-21 | James Madison (202) | 0 | 0 | Morgan State (337) | Cancelled | - | - |
| 14 | 2021-12-23 | Morgan State | 0 | 0 | Wisconsin | Cancelled | - | - |
| 15 | 2021-12-27 | Penn State-Wilkes-Barre | 0 | 0 | Morgan State (337) | Cancelled | - | - |
| 16 | 2021-12-27 | Penn State-Wilkes Barre | 0 | 0 | Morgan State (340) | Cancelled | - | - |
| 17 | 2021-12-29 | Morgan State | 0 | 0 | Kansas State | Cancelled | - | - |
| 18 | 2022-01-05 | Goucher | 41 | 100 | Morgan State (337) | Final | W | 59 |
| 19 | 2022-01-08 | Morgan State (337) | 0 | 0 | North Carolina Central (341) | Canceled | - | - |
| 20 | 2022-01-10 | Morgan State (329) | 88 | 81 | South Carolina State (304) | Final (OT) | W | 7 |
| 21 | 2022-01-15 | Coppin State (360) | 79 | 76 | Morgan State (337) | Final | L | -3 |
| 22 | 2022-01-22 | Howard (211) | 91 | 82 | Morgan State (337) | Final | L | -9 |
| 23 | 2022-01-24 | Morgan State (337) | 62 | 82 | Norfolk State (322) | Final | L | -20 |
| 24 | 2022-01-29 | Delaware State (361) | 0 | 0 | Morgan State (337) | Postponed | - | - |
| 25 | 2022-01-30 | Delaware State (357) | 70 | 82 | Morgan State (323) | Final | W | 12 |
| 26 | 2022-01-31 | Morgan State (323) | 72 | 79 | Maryland-Eastern Shore (282) | Final | L | -7 |
| 27 | 2022-02-12 | North Carolina Central (341) | 74 | 64 | Morgan State (337) | Final | L | -10 |
| 28 | 2022-02-14 | South Carolina State (355) | 66 | 76 | Morgan State (337) | Final | W | 10 |
| 29 | 2022-02-19 | Morgan State (332) | 66 | 68 | Howard (250) | Final | L | -2 |
| 30 | 2022-02-21 | Norfolk State (153) | 74 | 85 | Morgan State (323) | Final | W | 11 |
| 31 | 2022-02-26 | Morgan State (323) | 76 | 69 | Delaware State (358) | Final | W | 7 |
| 32 | 2022-02-28 | Maryland-Eastern Shore (285) | 48 | 82 | Morgan State (313) | Final | W | 34 |
| 33 | 2022-03-03 | Morgan State (313) | 63 | 59 | Coppin State (317) | Final | W | 4 |
| 34 | 2022-03-10 | South Carolina State (297) | 77 | 80 | Morgan State (298) | Final | W | 3 |
| 35 | 2022-03-11 | Morgan State (298) | 63 | 72 | Norfolk State (153) | Final | L | -9 |
| 36 | 2022-03-16 | Morgan State (337) | 65 | 70 | Youngstown State (231) | Final | L | -5 |