Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-10-21 | Stonehill | 71 | 95 | Providence (79) | Final | W | 24 |
| 2 | 2021-11-09 | Fairfield (266) | 73 | 80 | Providence (79) | Final | W | 7 |
| 3 | 2021-11-11 | Sacred Heart (235) | 64 | 92 | Providence (79) | Final | W | 28 |
| 4 | 2021-11-15 | Providence (51) | 63 | 58 | Wisconsin (62) | Final | W | 5 |
| 5 | 2021-11-18 | New Hampshire (212) | 58 | 69 | Providence (51) | Final | W | 11 |
| 6 | 2021-11-22 | Providence (82) | 77 | 72 | Northwestern (75) | Final | W | 5 |
| 7 | 2021-11-23 | Virginia (199) | 58 | 40 | Providence (24) | Final | L | -18 |
| 8 | 2021-11-27 | Saint Peter's (273) | 71 | 85 | Providence (24) | Final | W | 14 |
| 9 | 2021-12-01 | Texas Tech (20) | 68 | 72 | Providence (82) | Final | W | 4 |
| 10 | 2021-12-04 | Rhode Island (145) | 52 | 66 | Providence (82) | Final | W | 14 |
| 11 | 2021-12-07 | Vermont (225) | 58 | 68 | Providence (82) | Final | W | 10 |
| 12 | 2021-12-11 | Central Connecticut State (258) | 53 | 68 | Providence (82) | Final | W | 15 |
| 13 | 2021-12-18 | Providence (82) | 57 | 53 | Connecticut (4) | Final | W | 4 |
| 14 | 2021-12-22 | Georgetown (83) | 0 | 0 | Providence (82) | Postponed | - | - |
| 15 | 2021-12-29 | Seton Hall (53) | 65 | 70 | Providence (82) | Final | W | 5 |
| 16 | 2022-01-01 | Providence (82) | 70 | 53 | DePaul (95) | Final | W | 17 |
| 17 | 2022-01-04 | Providence (82) | 56 | 88 | Marquette (106) | Final | L | -32 |
| 18 | 2022-01-08 | St. John's (12) | 73 | 83 | Providence (82) | Final | W | 10 |
| 19 | 2022-01-11 | Providence (82) | 0 | 0 | Creighton (78) | Canceled | - | - |
| 20 | 2022-01-15 | Connecticut (4) | 0 | 0 | Providence (82) | Canceled | - | - |
| 21 | 2022-01-18 | Providence (82) | 0 | 0 | Seton Hall (53) | Canceled | - | - |
| 22 | 2022-01-20 | Georgetown (83) | 75 | 83 | Providence (82) | Final | W | 8 |
| 23 | 2022-01-23 | Butler (123) | 62 | 69 | Providence (13) | Final | W | 7 |
| 24 | 2022-01-26 | Providence (13) | 65 | 62 | Xavier (20) | Final | W | 3 |
| 25 | 2022-01-30 | Marquette (24) | 63 | 65 | Providence (10) | Final | W | 2 |
| 26 | 2022-02-01 | Providence (10) | 86 | 82 | St. John's (83) | Final | W | 4 |
| 27 | 2022-02-06 | Providence (82) | 71 | 52 | Georgetown (83) | Final | W | 19 |
| 28 | 2022-02-12 | DePaul (95) | 73 | 76 | Providence (82) | Final/OT | W | 3 |
| 29 | 2022-02-15 | Villanova (9) | 89 | 84 | Providence (8) | Final | L | -5 |
| 30 | 2022-02-20 | Providence (11) | 71 | 70 | Butler (112) | Final | W | 1 |
| 31 | 2022-02-23 | Xavier (29) | 92 | 99 | Providence (11) | Final | W | 7 |
| 32 | 2022-02-26 | Creighton (41) | 51 | 72 | Providence (11) | Final | W | 21 |
| 33 | 2022-03-01 | Providence (7) | 74 | 76 | Villanova (14) | Final | L | -2 |
| 34 | 2022-03-10 | Butler (114) | 61 | 65 | Providence (10) | Final | W | 4 |
| 35 | 2022-03-11 | Creighton (40) | 85 | 58 | Providence (10) | Final | L | -27 |
| 36 | 2022-03-17 | South Dakota State (50) | 57 | 66 | Providence (14) | Final | W | 9 |
| 37 | 2022-03-19 | Richmond (77) | 51 | 79 | Providence (14) | Final | W | 28 |
| 38 | 2022-03-25 | Providence (14) | 61 | 66 | Kansas (3) | Final | L | -5 |