Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-12 | Kent State (107) | 59 | 73 | Xavier (92) | Final | L | -14 |
| 2 | 2021-11-16 | Oberlin | 38 | 84 | Kent State (256) | Final | W | 46 |
| 3 | 2021-11-22 | Kent State (107) | 74 | 69 | James Madison (202) | Final | W | 5 |
| 4 | 2021-11-23 | George Washington (275) | 69 | 77 | Kent State (184) | Final | W | 8 |
| 5 | 2021-11-24 | East Tennessee State (140) | 57 | 51 | Kent State (107) | Final | L | -6 |
| 6 | 2021-11-30 | Point Park | 41 | 107 | Kent State (130) | Final | W | 66 |
| 7 | 2021-12-06 | Towson (125) | 73 | 58 | Kent State (121) | Final | L | -15 |
| 8 | 2021-12-09 | Detroit (270) | 52 | 69 | Kent State (121) | Final | W | 17 |
| 9 | 2021-12-12 | Kent State (107) | 50 | 63 | West Virginia (50) | Final | L | -13 |
| 10 | 2021-12-19 | Southern (259) | 78 | 76 | Kent State (107) | Final | L | -2 |
| 11 | 2021-12-21 | Tennessee-Martin (205) | 0 | 0 | Kent State (107) | Cancelled | - | - |
| 12 | 2021-12-21 | Cleveland State | 0 | 0 | Kent State | Cancelled | - | - |
| 13 | 2021-12-29 | Central Michigan (311) | 72 | 69 | Kent State (107) | Final | L | -3 |
| 14 | 2022-01-01 | Toledo (135) | 63 | 66 | Kent State (107) | Final | W | 3 |
| 15 | 2022-01-04 | Kent State (107) | 66 | 65 | Ball State (298) | Final | W | 1 |
| 16 | 2022-01-07 | Kent State (107) | 72 | 80 | Ohio (218) | Final | L | -8 |
| 17 | 2022-01-11 | Northern Illinois (326) | 65 | 63 | Kent State (107) | Final | L | -2 |
| 18 | 2022-01-14 | Akron (128) | 55 | 67 | Kent State (166) | Final | W | 12 |
| 19 | 2022-01-18 | Kent State (107) | 56 | 47 | Eastern Michigan (277) | Final | W | 9 |
| 20 | 2022-01-21 | Kent State (167) | 51 | 64 | Buffalo (152) | Final | L | -13 |
| 21 | 2022-01-25 | Western Michigan (342) | 64 | 75 | Kent State (179) | Final | W | 11 |
| 22 | 2022-01-29 | Kent State (107) | 91 | 83 | Bowling Green (168) | Final | W | 8 |
| 23 | 2022-02-01 | Kent State (171) | 78 | 65 | Miami (OH) (244) | Final | W | 13 |
| 24 | 2022-02-05 | Eastern Michigan (277) | 71 | 90 | Kent State (107) | Final | W | 19 |
| 25 | 2022-02-08 | Bowling Green (216) | 68 | 76 | Kent State (159) | Final | W | 8 |
| 26 | 2022-02-11 | Kent State (107) | 66 | 64 | Akron (59) | Final | W | 2 |
| 27 | 2022-02-12 | Kent State (159) | 66 | 64 | Akron (121) | Final | W | 2 |
| 28 | 2022-02-15 | Kent State (140) | 72 | 59 | Toledo (63) | Final | W | 13 |
| 29 | 2022-02-18 | Ohio (61) | 52 | 75 | Kent State (140) | Final | W | 23 |
| 30 | 2022-02-22 | Ball State (249) | 82 | 93 | Kent State (119) | Final | W | 11 |
| 31 | 2022-02-26 | Kent State (119) | 73 | 71 | Central Michigan (312) | Final | W | 2 |
| 32 | 2022-03-01 | Kent State (118) | 63 | 55 | Northern Illinois (297) | Final | W | 8 |
| 33 | 2022-03-04 | Buffalo (116) | 65 | 70 | Kent State (118) | Final | W | 5 |
| 34 | 2022-03-10 | Miami (OH) (256) | 75 | 85 | Kent State (115) | Final | W | 10 |
| 35 | 2022-03-11 | Ohio (106) | 61 | 67 | Kent State (115) | Final | W | 6 |
| 36 | 2022-03-12 | Akron (132) | 75 | 55 | Kent State (115) | Final | L | -20 |
| 37 | 2022-03-16 | Kent State (107) | 79 | 83 | Southern Utah (282) | Final | L | -4 |