Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-04 | Capital | 44 | 69 | Miami (OH) (193) | Final | W | 25 |
| 2 | 2021-11-09 | Miami (OH) (193) | 72 | 69 | Georgia Tech (36) | Final | W | 3 |
| 3 | 2021-11-13 | Lamar (295) | 75 | 104 | Miami (OH) (193) | Final | W | 29 |
| 4 | 2021-11-17 | Stetson (301) | 65 | 80 | Miami (OH) (40) | Final | W | 15 |
| 5 | 2021-11-20 | Heidelberg | 45 | 90 | Miami (OH) (40) | Final | W | 45 |
| 6 | 2021-11-23 | Defiance | 47 | 99 | Miami (OH) (51) | Final | W | 52 |
| 7 | 2021-11-27 | Miami (OH) (51) | 67 | 79 | Western Illinois (144) | Final | L | -12 |
| 8 | 2021-12-01 | Cincinnati (54) | 59 | 58 | Miami (OH) (40) | Final | L | -1 |
| 9 | 2021-12-04 | Miami (OH) (40) | 68 | 69 | Indiana State (243) | Final | L | -1 |
| 10 | 2021-12-14 | Miami (OH) (40) | 76 | 89 | Clemson (36) | Final | L | -13 |
| 11 | 2021-12-18 | Bellarmine (266) | 77 | 68 | Miami (OH) (40) | Final | L | -9 |
| 12 | 2021-12-21 | Spalding | 56 | 80 | Miami (OH) (40) | Final | W | 24 |
| 13 | 2021-12-29 | Miami (OH) (40) | 91 | 81 | Buffalo (219) | Final | W | 10 |
| 14 | 2022-01-01 | Central Michigan (311) | 0 | 0 | Miami (OH) (40) | Postponed | - | - |
| 15 | 2022-01-04 | Miami (OH) (40) | 0 | 0 | Bowling Green (168) | Postponed | - | - |
| 16 | 2022-01-08 | Akron (59) | 0 | 0 | Miami (OH) (40) | Postponed | - | - |
| 17 | 2022-01-08 | Miami (OH) (40) | 83 | 87 | Bowling Green (168) | Final/OT | L | -4 |
| 18 | 2022-01-11 | Toledo (135) | 75 | 72 | Miami (OH) (40) | Final | L | -3 |
| 19 | 2022-01-15 | Miami (OH) (40) | 70 | 62 | Western Michigan (304) | Final | W | 8 |
| 20 | 2022-01-18 | Ohio (218) | 86 | 63 | Miami (OH) (40) | Final | L | -23 |
| 21 | 2022-01-22 | Northern Illinois (326) | 82 | 85 | Miami (OH) (40) | Final/OT | W | 3 |
| 22 | 2022-01-25 | Miami (OH) (212) | 64 | 81 | Ball State (269) | Final | L | -17 |
| 23 | 2022-01-29 | Miami (OH) (40) | 75 | 85 | Eastern Michigan (277) | Final | L | -10 |
| 24 | 2022-02-01 | Kent State (171) | 78 | 65 | Miami (OH) (244) | Final | L | -13 |
| 25 | 2022-02-04 | Miami (OH) (244) | 55 | 66 | Akron (127) | Final | L | -11 |
| 26 | 2022-02-06 | Akron (59) | 71 | 59 | Miami (OH) (40) | Final | L | -12 |
| 27 | 2022-02-08 | Western Michigan (350) | 57 | 62 | Miami (OH) (268) | Final | W | 5 |
| 28 | 2022-02-12 | Bowling Green (168) | 78 | 94 | Miami (OH) (40) | Final | W | 16 |
| 29 | 2022-02-15 | Miami (OH) (255) | 78 | 91 | Ohio (61) | Final | L | -13 |
| 30 | 2022-02-19 | Miami (OH) (255) | 78 | 75 | Northern Illinois (300) | Final | W | 3 |
| 31 | 2022-02-22 | Buffalo (125) | 86 | 84 | Miami (OH) (251) | Final | L | -2 |
| 32 | 2022-02-24 | Central Michigan (312) | 83 | 69 | Miami (OH) (251) | Final | L | -14 |
| 33 | 2022-02-26 | Miami (OH) (251) | 73 | 88 | Toledo (79) | Final | L | -15 |
| 34 | 2022-03-01 | Miami (OH) (274) | 75 | 61 | Central Michigan (305) | Final | W | 14 |
| 35 | 2022-03-04 | Eastern Michigan (283) | 63 | 76 | Miami (OH) (274) | Final | W | 13 |
| 36 | 2022-03-10 | Miami (OH) (256) | 75 | 85 | Kent State (115) | Final | L | -10 |