Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Delaware (240) | 71 | 93 | Davidson (74) | Final | L | -22 |
| 2 | 2021-11-13 | Delaware (240) | 83 | 63 | Siena (142) | Final | W | 20 |
| 3 | 2021-11-17 | La Salle (237) | 82 | 85 | Delaware (287) | Final/OT | W | 3 |
| 4 | 2021-11-22 | Delaware (287) | 75 | 68 | Appalachian State (159) | Final | W | 7 |
| 5 | 2021-11-23 | Delaware (159) | 81 | 71 | Fordham (200) | Final | W | 10 |
| 6 | 2021-11-24 | Delaware (287) | 73 | 81 | Oakland (172) | Final | L | -8 |
| 7 | 2021-11-27 | Delaware (159) | 74 | 75 | Temple (174) | Final | L | -1 |
| 8 | 2021-11-30 | Long Island (306) | 67 | 75 | Delaware (141) | Final | W | 8 |
| 9 | 2021-12-02 | Delaware (141) | 59 | 48 | Delaware State (357) | Final | W | 11 |
| 10 | 2021-12-05 | UMBC (174) | 60 | 70 | Delaware (141) | Final | W | 10 |
| 11 | 2021-12-08 | Lafayette (294) | 58 | 68 | Delaware (114) | Final | W | 10 |
| 12 | 2021-12-10 | Moravian | 55 | 94 | Delaware (114) | Final | W | 39 |
| 13 | 2021-12-21 | Delaware (287) | 72 | 83 | Iona (220) | Final | L | -11 |
| 14 | 2021-12-29 | Delaware (287) | 68 | 70 | UNC-Wilmington (90) | Final | L | -2 |
| 15 | 2021-12-31 | Delaware (287) | 67 | 66 | Charleston (123) | Final | W | 1 |
| 16 | 2022-01-03 | James Madison (202) | 0 | 0 | Delaware (287) | Postponed | - | - |
| 17 | 2022-01-05 | Towson (152) | 0 | 0 | Delaware (287) | Postponed | - | - |
| 18 | 2022-01-11 | Delaware (287) | 81 | 77 | Drexel (215) | Final | W | 4 |
| 19 | 2022-01-15 | Delaware (287) | 77 | 82 | Hofstra (98) | Final | L | -5 |
| 20 | 2022-01-17 | Delaware (125) | 82 | 76 | Northeastern (255) | Final (OT) | W | 6 |
| 21 | 2022-01-20 | William & Mary (141) | 74 | 84 | Delaware (287) | Final | W | 10 |
| 22 | 2022-01-22 | Elon (232) | 77 | 80 | Delaware (287) | Final | W | 3 |
| 23 | 2022-01-24 | Towson (152) | 69 | 62 | Delaware (287) | Final | L | -7 |
| 24 | 2022-01-27 | Delaware (287) | 0 | 0 | Towson (152) | Suspended | - | - |
| 25 | 2022-01-29 | Delaware (287) | 85 | 69 | James Madison (202) | Final | W | 16 |
| 26 | 2022-02-03 | Drexel (215) | 76 | 68 | Delaware (287) | Final | L | -8 |
| 27 | 2022-02-10 | Northeastern (300) | 61 | 74 | Delaware (287) | Final | W | 13 |
| 28 | 2022-02-12 | Hofstra (98) | 80 | 66 | Delaware (287) | Final | L | -14 |
| 29 | 2022-02-14 | James Madison (202) | 60 | 81 | Delaware (287) | Final | W | 21 |
| 30 | 2022-02-17 | Delaware (287) | 71 | 62 | Elon (232) | Final | W | 9 |
| 31 | 2022-02-19 | Delaware (125) | 73 | 69 | William & Mary (330) | Final | W | 4 |
| 32 | 2022-02-24 | Charleston (163) | 99 | 96 | Delaware (116) | Final | L | -3 |
| 33 | 2022-02-26 | UNC-Wilmington (147) | 69 | 62 | Delaware (116) | Final | L | -7 |
| 34 | 2022-02-28 | Delaware (127) | 57 | 69 | Towson (81) | Final | L | -12 |
| 35 | 2022-03-06 | Delaware (134) | 66 | 56 | Drexel (174) | Final | W | 10 |
| 36 | 2022-03-07 | Delaware (134) | 69 | 56 | Towson (75) | Final | W | 13 |
| 37 | 2022-03-08 | Delaware (134) | 59 | 55 | UNC-Wilmington (126) | Final | W | 4 |
| 38 | 2022-03-18 | Delaware (121) | 60 | 80 | Villanova (7) | Final | L | -20 |