Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Long Island (210) | 64 | 98 | San Francisco (124) | Final | L | -34 |
| 2 | 2021-11-12 | Long Island (175) | 60 | 84 | Fresno State (153) | Final | L | -24 |
| 3 | 2021-11-17 | Long Island (175) | 40 | 93 | Connecticut (4) | Final | L | -53 |
| 4 | 2021-11-23 | Long Island (327) | 62 | 64 | Saint Peter's (273) | Final | L | -2 |
| 5 | 2021-11-27 | Delaware State (355) | 65 | 99 | Long Island (327) | Final | W | 34 |
| 6 | 2021-11-30 | Long Island (306) | 67 | 75 | Delaware (141) | Final | L | -8 |
| 7 | 2021-12-02 | Long Island (306) | 63 | 72 | Towson (128) | Final | L | -9 |
| 8 | 2021-12-09 | Long Island (310) | 57 | 73 | Fordham (174) | Final | L | -16 |
| 9 | 2021-12-13 | Merchant Marine | 48 | 106 | Long Island (324) | Final | W | 58 |
| 10 | 2021-12-19 | Army (339) | 65 | 90 | Long Island (175) | Final | W | 25 |
| 11 | 2021-12-21 | UMass-Lowell (319) | 0 | 0 | Long Island (175) | Cancelled | - | - |
| 12 | 2021-12-29 | Long Island (175) | 65 | 69 | Sacred Heart (270) | Final | L | -4 |
| 13 | 2021-12-31 | Long Island (175) | 77 | 82 | Merrimack (134) | Final | L | -5 |
| 14 | 2022-01-06 | Mount St Mary's (257) | 57 | 74 | Long Island (175) | Final | W | 17 |
| 15 | 2022-01-08 | St. Francis (PA) (321) | 70 | 75 | Long Island (306) | Final (OT) | W | 5 |
| 16 | 2022-01-15 | Central Connecticut State (258) | 61 | 83 | Long Island (175) | Final | W | 22 |
| 17 | 2022-01-17 | Long Island (273) | 80 | 65 | St. Francis (NY) (330) | Final | W | 15 |
| 18 | 2022-01-21 | Wagner (82) | 92 | 85 | Long Island (273) | Final (OT) | L | -7 |
| 19 | 2022-01-23 | Long Island (261) | 79 | 75 | Fairleigh Dickinson (352) | Final | W | 4 |
| 20 | 2022-01-27 | Long Island (175) | 62 | 65 | Central Connecticut State (258) | Final | L | -3 |
| 21 | 2022-01-30 | Long Island (281) | 81 | 88 | Bryant (196) | Final | L | -7 |
| 22 | 2022-02-03 | Sacred Heart (270) | 75 | 79 | Long Island (175) | Final | W | 4 |
| 23 | 2022-02-05 | Long Island (175) | 64 | 79 | Wagner (316) | Final | L | -15 |
| 24 | 2022-02-10 | St. Francis (NY) | 69 | 74 | Long Island (175) | Final | W | 5 |
| 25 | 2022-02-12 | Bryant (349) | 88 | 99 | Long Island (175) | Final | W | 11 |
| 26 | 2022-02-17 | Long Island (175) | 81 | 63 | Saint Francis (354) | Final | W | 18 |
| 27 | 2022-02-17 | Long Island (272) | 81 | 63 | St. Francis (PA) (323) | Final | W | 18 |
| 28 | 2022-02-19 | Long Island (272) | 66 | 61 | Mount St Mary's (258) | Final | W | 5 |
| 29 | 2022-02-24 | Merrimack (279) | 74 | 85 | Long Island (257) | Final | W | 11 |
| 30 | 2022-02-26 | Fairleigh Dickinson (354) | 77 | 84 | Long Island (257) | Final | W | 7 |
| 31 | 2022-03-02 | Sacred Heart (323) | 75 | 82 | Long Island (247) | Final | W | 7 |
| 32 | 2022-03-05 | Long Island (247) | 62 | 82 | Wagner (123) | Final | L | -20 |