Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-04 | Colorado Christian | 45 | 63 | BYU (13) | Final | W | 18 |
| 2 | 2021-11-09 | Cleveland State (139) | 59 | 69 | BYU (13) | Final | W | 10 |
| 3 | 2021-11-12 | San Diego State (48) | 60 | 66 | BYU (23) | Final | W | 6 |
| 4 | 2021-11-16 | BYU (52) | 81 | 49 | Oregon (32) | Final | W | 32 |
| 5 | 2021-11-20 | Central Methodist | 61 | 97 | BYU (23) | Final | W | 36 |
| 6 | 2021-11-24 | Texas Southern (317) | 64 | 81 | BYU (23) | Final | W | 17 |
| 7 | 2021-11-27 | BYU (27) | 75 | 64 | Utah (7) | Final | W | 11 |
| 8 | 2021-12-01 | BYU (23) | 65 | 72 | Utah Valley (91) | Final/OT | L | -7 |
| 9 | 2021-12-04 | BYU (23) | 74 | 68 | Missouri State (224) | Final | W | 6 |
| 10 | 2021-12-08 | Utah State (66) | 71 | 82 | BYU (39) | Final | W | 11 |
| 11 | 2021-12-11 | BYU (23) | 71 | 83 | Creighton (78) | Final | L | -12 |
| 12 | 2021-12-18 | BYU (23) | 89 | 71 | Weber State (235) | Final | W | 18 |
| 13 | 2021-12-22 | BYU (23) | 54 | 39 | South Florida (52) | Final | W | 15 |
| 14 | 2021-12-23 | BYU (23) | 67 | 69 | Vanderbilt (17) | Final | L | -2 |
| 15 | 2021-12-25 | Liberty (93) | 75 | 80 | BYU (23) | Final | W | 5 |
| 16 | 2021-12-29 | Westminster (UT) | 53 | 65 | BYU (23) | Final | W | 12 |
| 17 | 2022-01-01 | BYU (23) | 0 | 0 | Portland (210) | Canceled | - | - |
| 18 | 2022-01-06 | Pacific (132) | 51 | 73 | BYU (23) | Final | W | 22 |
| 19 | 2022-01-08 | Saint Mary's (33) | 43 | 52 | BYU (23) | Final | W | 9 |
| 20 | 2022-01-13 | BYU (23) | 84 | 110 | Gonzaga (11) | Final | L | -26 |
| 21 | 2022-01-15 | BYU (23) | 71 | 69 | San Francisco (122) | Final | W | 2 |
| 22 | 2022-01-20 | San Diego (246) | 71 | 79 | BYU (23) | Final | W | 8 |
| 23 | 2022-01-22 | Portland (210) | 65 | 78 | BYU (23) | Final | W | 13 |
| 24 | 2022-01-27 | BYU (23) | 76 | 77 | Santa Clara (42) | Final | L | -1 |
| 25 | 2022-01-29 | BYU (23) | 73 | 76 | Pacific (132) | Final | L | -3 |
| 26 | 2022-02-03 | San Francisco (122) | 73 | 59 | BYU (23) | Final | L | -14 |
| 27 | 2022-02-05 | Gonzaga (11) | 90 | 57 | BYU (23) | Final | L | -33 |
| 28 | 2022-02-10 | BYU (23) | 83 | 82 | Loyola Marymount (184) | Final/OT | W | 1 |
| 29 | 2022-02-12 | BYU (23) | 91 | 85 | Pepperdine (283) | Final | W | 6 |
| 30 | 2022-02-19 | BYU (62) | 64 | 69 | Saint Mary's (31) | Final | L | -5 |
| 31 | 2022-02-24 | Loyola Marymount (211) | 59 | 79 | BYU (68) | Final | W | 20 |
| 32 | 2022-02-26 | Pepperdine (286) | 59 | 75 | BYU (68) | Final | W | 16 |
| 33 | 2022-03-04 | Loyola Marymount (209) | 60 | 85 | BYU (59) | Final | W | 25 |
| 34 | 2022-03-05 | BYU (59) | 63 | 75 | San Francisco (37) | Final | L | -12 |
| 35 | 2022-03-16 | Long Beach State (278) | 72 | 93 | BYU (23) | Final | W | 21 |
| 36 | 2022-03-19 | Northern Iowa (105) | 71 | 90 | BYU (64) | Final | W | 19 |
| 37 | 2022-03-23 | Washington State (69) | 77 | 58 | BYU (64) | Final | L | -19 |