Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Bridgewater | 56 | 79 | Norfolk State (188) | Final | W | 23 |
| 2 | 2021-11-11 | Penn State-Wilkes Barre | 55 | 111 | Norfolk State (188) | Final | W | 56 |
| 3 | 2021-11-13 | Norfolk State (188) | 66 | 59 | Tennessee State (336) | Final | W | 7 |
| 4 | 2021-11-16 | William & Mary (292) | 74 | 91 | Norfolk State (113) | Final | W | 17 |
| 5 | 2021-11-19 | Norfolk State (322) | 90 | 84 | Bowling Green (168) | Final | W | 6 |
| 6 | 2021-11-21 | Norfolk State (137) | 48 | 88 | Xavier (8) | Final | L | -40 |
| 7 | 2021-11-23 | Regent | 20 | 95 | Norfolk State (137) | Final | W | 75 |
| 8 | 2021-11-28 | Hampton (320) | 61 | 70 | Norfolk State (113) | Final | W | 9 |
| 9 | 2021-11-30 | Norfolk State (113) | 70 | 63 | Grambling (298) | Final | W | 7 |
| 10 | 2021-12-01 | Norfolk State (322) | 74 | 69 | UNC-Wilmington (90) | Final | W | 5 |
| 11 | 2021-12-04 | Norfolk State (322) | 57 | 58 | Hampton (260) | Final | L | -1 |
| 12 | 2021-12-11 | Norfolk State (322) | 58 | 71 | Wichita State (76) | Final | L | -13 |
| 13 | 2021-12-19 | Norfolk State (322) | 0 | 0 | Loyola-Chicago (263) | Cancelled | - | - |
| 14 | 2021-12-21 | Norfolk State (322) | 54 | 68 | New Mexico (49) | Final | L | -14 |
| 15 | 2021-12-29 | Norfolk State (322) | 0 | 0 | Campbell (191) | Cancelled | - | - |
| 16 | 2022-01-08 | Norfolk State (322) | 0 | 0 | Maryland-Eastern Shore (353) | Postponed | - | - |
| 17 | 2022-01-12 | Delaware State (358) | 51 | 80 | Norfolk State (187) | Final | W | 29 |
| 18 | 2022-01-15 | Norfolk State (322) | 77 | 74 | Howard (211) | Final | W | 3 |
| 19 | 2022-01-17 | Norfolk State (172) | 72 | 58 | Maryland-Eastern Shore (245) | Final | W | 14 |
| 20 | 2022-01-22 | Coppin State (360) | 77 | 84 | Norfolk State (322) | Final | W | 7 |
| 21 | 2022-01-24 | Morgan State (337) | 62 | 82 | Norfolk State (322) | Final | W | 20 |
| 22 | 2022-01-29 | Norfolk State (322) | 87 | 69 | South Carolina State (355) | Final | W | 18 |
| 23 | 2022-01-31 | Norfolk State (134) | 67 | 70 | North Carolina Central (280) | Final | L | -3 |
| 24 | 2022-02-12 | Maryland-Eastern Shore (353) | 63 | 70 | Norfolk State (322) | Final | W | 7 |
| 25 | 2022-02-14 | Norfolk State (322) | 69 | 66 | Delaware State (361) | Final | W | 3 |
| 26 | 2022-02-19 | Norfolk State (158) | 89 | 59 | Coppin State (313) | Final | W | 30 |
| 27 | 2022-02-21 | Norfolk State (153) | 74 | 85 | Morgan State (323) | Final | L | -11 |
| 28 | 2022-02-26 | South Carolina State (296) | 59 | 63 | Norfolk State (153) | Final | W | 4 |
| 29 | 2022-02-28 | North Carolina Central (275) | 46 | 75 | Norfolk State (171) | Final | W | 29 |
| 30 | 2022-03-03 | Howard (243) | 61 | 83 | Norfolk State (171) | Final | W | 22 |
| 31 | 2022-03-09 | Delaware State (358) | 66 | 74 | Norfolk State (153) | Final | W | 8 |
| 32 | 2022-03-11 | Morgan State (298) | 63 | 72 | Norfolk State (153) | Final | W | 9 |
| 33 | 2022-03-12 | Coppin State (319) | 57 | 72 | Norfolk State (153) | Final | W | 15 |
| 34 | 2022-03-17 | Norfolk State (147) | 49 | 85 | Baylor (4) | Final | L | -36 |