Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-10 | Florida A&M (309) | 57 | 67 | Kansas State (185) | Final | L | -10 |
| 2 | 2021-11-15 | LeMoyne-Owen | 70 | 95 | Florida A&M (264) | Final | W | 25 |
| 3 | 2021-11-21 | Florida A&M (298) | 59 | 86 | Miami (100) | Final | L | -27 |
| 4 | 2021-11-24 | Florida A&M (297) | 53 | 67 | UTEP (274) | Final | L | -14 |
| 5 | 2021-11-26 | Florida A&M (297) | 49 | 60 | UC-Riverside (292) | Final | L | -11 |
| 6 | 2021-12-01 | Fort Valley State | 63 | 76 | Florida A&M (297) | Final | W | 13 |
| 7 | 2021-12-07 | Florida Gulf Coast (241) | 69 | 55 | Florida A&M (297) | Final | L | -14 |
| 8 | 2021-12-12 | Florida A&M (297) | 66 | 73 | Akron (59) | Final | L | -7 |
| 9 | 2021-12-14 | Florida A&M (297) | 50 | 77 | Cincinnati (54) | Final | L | -27 |
| 10 | 2021-12-17 | Florida A&M (297) | 66 | 80 | Santa Clara (42) | Final | L | -14 |
| 11 | 2021-12-19 | Florida A&M (297) | 62 | 73 | UC-Santa Barbara (171) | Final | L | -11 |
| 12 | 2021-12-21 | Florida A&M (297) | 0 | 0 | Arizona State (61) | Cancelled | - | - |
| 13 | 2021-12-29 | Florida A&M (297) | 0 | 0 | Illinois (9) | Cancelled | - | - |
| 14 | 2022-01-03 | Florida A&M (297) | 59 | 66 | Bethune-Cookman (240) | Final | L | -7 |
| 15 | 2022-01-08 | Southern (259) | 80 | 66 | Florida A&M (297) | Final | L | -14 |
| 16 | 2022-01-10 | Grambling (325) | 66 | 75 | Florida A&M (350) | Final | W | 9 |
| 17 | 2022-01-15 | Florida A&M (297) | 71 | 66 | Arkansas-Pine Bluff (303) | Final/OT | W | 5 |
| 18 | 2022-01-17 | Florida A&M (331) | 78 | 70 | Mississippi Valley State (356) | Final | W | 8 |
| 19 | 2022-01-22 | Alcorn State (348) | 68 | 70 | Florida A&M (297) | Final | W | 2 |
| 20 | 2022-01-24 | Jackson State (329) | 64 | 67 | Florida A&M (297) | Final | W | 3 |
| 21 | 2022-01-29 | Florida A&M (297) | 65 | 60 | Alabama A&M (286) | Final | W | 5 |
| 22 | 2022-01-31 | Florida A&M (300) | 66 | 65 | Alabama State (339) | Final | W | 1 |
| 23 | 2022-02-05 | Texas Southern (317) | 67 | 55 | Florida A&M (297) | Final | L | -12 |
| 24 | 2022-02-07 | Prairie View A&M (285) | 60 | 61 | Florida A&M (297) | Final | W | 1 |
| 25 | 2022-02-12 | Florida A&M (297) | 56 | 60 | Jackson State (329) | Final | L | -4 |
| 26 | 2022-02-14 | Florida A&M (297) | 56 | 68 | Alcorn State (348) | Final | L | -12 |
| 27 | 2022-02-14 | Florida A&M (303) | 58 | 68 | Alcorn State (291) | Final | L | -10 |
| 28 | 2022-02-19 | Alabama State (338) | 83 | 86 | Florida A&M (303) | Final | W | 3 |
| 29 | 2022-02-21 | Alabama A&M (337) | 71 | 63 | Florida A&M (308) | Final | L | -8 |
| 30 | 2022-02-26 | Florida A&M (308) | 79 | 73 | Grambling (297) | Final | W | 6 |
| 31 | 2022-02-28 | Florida A&M (309) | 51 | 58 | Southern (232) | Final | L | -7 |
| 32 | 2022-03-05 | Bethune-Cookman (341) | 73 | 84 | Florida A&M (309) | Final | W | 11 |
| 33 | 2022-03-10 | Alabama A&M (320) | 61 | 56 | Florida A&M (304) | Final | L | -5 |