Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-23 | Defiance | 47 | 99 | Miami (OH) (51) | Final | L | -52 |
| 2 | 2021-12-05 | Defiance | 43 | 92 | Bellarmine (246) | Final | L | -49 |
| 3 | 2021-12-29 | Defiance | 56 | 96 | Youngstown State (231) | Final | L | -40 |