Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Fisher College | 54 | 122 | Bryant (118) | Final | W | 68 |
| 2 | 2021-11-10 | Fisher College | 54 | 122 | Bryant (118) | Final | W | 68 |
| 3 | 2021-11-12 | Bryant (349) | 64 | 83 | Rhode Island (145) | Final | L | -19 |
| 4 | 2021-11-15 | Bryant (160) | 70 | 93 | Clemson (38) | Final | L | -23 |
| 5 | 2021-11-20 | Bryant (349) | 75 | 81 | Bethune-Cookman (240) | Final | L | -6 |
| 6 | 2021-11-21 | Bryant (231) | 78 | 62 | Holy Cross (336) | Final | W | 16 |
| 7 | 2021-11-26 | Bryant (349) | 65 | 59 | Brown (295) | Final | W | 6 |
| 8 | 2021-11-28 | Dartmouth (144) | 63 | 61 | Bryant (214) | Final (OT) | L | -2 |
| 9 | 2021-12-03 | Bryant (349) | 44 | 111 | Houston (5) | Final | L | -67 |
| 10 | 2021-12-05 | Bryant (214) | 58 | 73 | Cincinnati (57) | Final | L | -15 |
| 11 | 2021-12-08 | New Hampshire (123) | 59 | 76 | Bryant (261) | Final | W | 17 |
| 12 | 2021-12-11 | Bryant (349) | 78 | 86 | Stony Brook (213) | Final | L | -8 |
| 13 | 2021-12-19 | Bryant (349) | 0 | 0 | Cornell (187) | Cancelled | - | - |
| 14 | 2021-12-22 | Eastern Kentucky (288) | 0 | 0 | Bryant (349) | Cancelled | - | - |
| 15 | 2021-12-29 | Bryant (349) | 80 | 76 | Central Connecticut State (258) | Final | W | 4 |
| 16 | 2021-12-31 | Sacred Heart (270) | 82 | 85 | Bryant (349) | Final | W | 3 |
| 17 | 2022-01-06 | Bryant (349) | 81 | 84 | Wagner (316) | Final/OT | L | -3 |
| 18 | 2022-01-08 | Bryant (349) | 2 | 0 | Fairleigh Dickinson (343) | Forfeit | W | 2 |
| 19 | 2022-01-15 | Mount St Mary's (257) | 66 | 73 | Bryant (349) | Final | W | 7 |
| 20 | 2022-01-17 | St. Francis (PA) (325) | 52 | 82 | Bryant (236) | Final | W | 30 |
| 21 | 2022-01-21 | Bryant (236) | 79 | 63 | Merrimack (287) | Final | W | 16 |
| 22 | 2022-01-23 | St. Francis (NY) (334) | 68 | 85 | Bryant (206) | Final | W | 17 |
| 23 | 2022-01-27 | Merrimack (134) | 67 | 76 | Bryant (349) | Final | W | 9 |
| 24 | 2022-01-30 | Long Island (281) | 81 | 88 | Bryant (196) | Final | W | 7 |
| 25 | 2022-02-03 | Bryant (349) | 89 | 82 | Saint Francis (354) | Final | W | 7 |
| 26 | 2022-02-03 | Bryant (196) | 89 | 82 | St. Francis (PA) (320) | Final | W | 7 |
| 27 | 2022-02-05 | Bryant (349) | 62 | 61 | Mount St Mary's (257) | Final | W | 1 |
| 28 | 2022-02-10 | Bryant (349) | 99 | 86 | Sacred Heart (270) | Final | W | 13 |
| 29 | 2022-02-12 | Bryant (349) | 88 | 99 | Long Island (175) | Final | L | -11 |
| 30 | 2022-02-17 | Central Connecticut State (258) | 61 | 75 | Bryant (349) | Final | W | 14 |
| 31 | 2022-02-19 | Fairleigh Dickinson (354) | 93 | 105 | Bryant (202) | Final | W | 12 |
| 32 | 2022-02-24 | Bryant (204) | 86 | 69 | St. Francis (NY) (315) | Final | W | 17 |
| 33 | 2022-02-26 | Wagner (96) | 70 | 78 | Bryant (204) | Final | W | 8 |
| 34 | 2022-03-02 | Central Connecticut State (347) | 59 | 73 | Bryant (191) | Final | W | 14 |
| 35 | 2022-03-05 | Mount St Mary's (292) | 69 | 70 | Bryant (191) | Final | W | 1 |
| 36 | 2022-03-08 | Wagner (116) | 43 | 70 | Bryant (189) | Final | W | 27 |
| 37 | 2022-03-16 | Bryant (349) | 82 | 93 | Wright State (124) | Final | L | -11 |