Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Central Connecticut State (299) | 48 | 99 | Connecticut (32) | Final | L | -51 |
| 2 | 2021-11-14 | Central Connecticut State (258) | 57 | 75 | Brown (295) | Final | L | -18 |
| 3 | 2021-11-16 | North Carolina State (75) | 79 | 65 | Central Connecticut State (348) | Final | L | -14 |
| 4 | 2021-11-17 | Central Connecticut State (258) | 53 | 77 | UMass-Lowell (319) | Final | L | -24 |
| 5 | 2021-11-20 | Central Connecticut State (258) | 65 | 76 | Quinnipiac (189) | Final | L | -11 |
| 6 | 2021-11-23 | Central Connecticut State (353) | 64 | 56 | Maine (292) | Final | W | 8 |
| 7 | 2021-11-28 | Fordham (163) | 89 | 83 | Central Connecticut State (338) | Final (2OT) | L | -6 |
| 8 | 2021-12-01 | Holy Cross (334) | 67 | 73 | Central Connecticut State (258) | Final | W | 6 |
| 9 | 2021-12-04 | Central Connecticut State (258) | 45 | 67 | New Hampshire (346) | Final | L | -22 |
| 10 | 2021-12-11 | Central Connecticut State (258) | 53 | 68 | Providence (82) | Final | L | -15 |
| 11 | 2021-12-14 | Central Connecticut State (258) | 67 | 87 | Stony Brook (213) | Final | L | -20 |
| 12 | 2021-12-18 | Hartford | 65 | 75 | Central Connecticut State (258) | Final | W | 10 |
| 13 | 2021-12-23 | Central Connecticut State (258) | 0 | 0 | Rutgers (112) | Postponed | - | - |
| 14 | 2021-12-29 | Bryant (349) | 80 | 76 | Central Connecticut State (258) | Final | L | -4 |
| 15 | 2021-12-31 | Central Connecticut State (258) | 67 | 55 | St. Francis (NY) | Final | W | 12 |
| 16 | 2022-01-01 | Central Connecticut State (258) | 48 | 79 | Rutgers (112) | Final | L | -31 |
| 17 | 2022-01-06 | Sacred Heart (270) | 0 | 2 | Central Connecticut State (258) | Forfeit | W | 2 |
| 18 | 2022-01-08 | Merrimack (134) | 66 | 57 | Central Connecticut State (258) | Final | L | -9 |
| 19 | 2022-01-15 | Central Connecticut State (258) | 61 | 83 | Long Island (175) | Final | L | -22 |
| 20 | 2022-01-17 | Central Connecticut State (332) | 66 | 74 | Sacred Heart (298) | Final | L | -8 |
| 21 | 2022-01-21 | Central Connecticut State (332) | 67 | 68 | St. Francis (PA) (325) | Final | L | -1 |
| 22 | 2022-01-23 | Central Connecticut State (345) | 50 | 65 | Mount St Mary's (272) | Final | L | -15 |
| 23 | 2022-01-27 | Long Island (175) | 62 | 65 | Central Connecticut State (258) | Final | W | 3 |
| 24 | 2022-01-30 | Central Connecticut State (343) | 55 | 75 | Fairleigh Dickinson (349) | Final | L | -20 |
| 25 | 2022-02-03 | Wagner (316) | 54 | 52 | Central Connecticut State (258) | Final | L | -2 |
| 26 | 2022-02-05 | Fairleigh Dickinson (343) | 82 | 91 | Central Connecticut State (258) | Final/OT | W | 9 |
| 27 | 2022-02-10 | Central Connecticut State (258) | 60 | 57 | Merrimack (134) | Final | W | 3 |
| 28 | 2022-02-12 | St. Francis (NY) | 67 | 50 | Central Connecticut State (258) | Final | L | -17 |
| 29 | 2022-02-17 | Central Connecticut State (258) | 61 | 75 | Bryant (349) | Final | L | -14 |
| 30 | 2022-02-19 | Central Connecticut State (344) | 68 | 78 | Wagner (94) | Final | L | -10 |
| 31 | 2022-02-24 | St. Francis (PA) (335) | 79 | 63 | Central Connecticut State (345) | Final | L | -16 |
| 32 | 2022-02-26 | Mount St Mary's (289) | 65 | 46 | Central Connecticut State (345) | Final | L | -19 |
| 33 | 2022-02-28 | Central Connecticut State (347) | 67 | 66 | Fairleigh Dickinson (353) | Final | W | 1 |
| 34 | 2022-03-02 | Central Connecticut State (347) | 59 | 73 | Bryant (191) | Final | L | -14 |