Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Hartford (161) | 59 | 77 | Wagner (160) | Final | W | 18 |
| 2 | 2021-11-13 | Wagner (160) | 58 | 44 | Virginia Commonwealth (38) | Final | W | 14 |
| 3 | 2021-11-17 | Saint Peter's (200) | 0 | 0 | Wagner (316) | Cancelled | - | - |
| 4 | 2021-11-20 | NJIT (306) | 0 | 0 | Wagner (316) | Cancelled | - | - |
| 5 | 2021-11-24 | Wagner (316) | 0 | 0 | Army (339) | Cancelled | - | - |
| 6 | 2021-12-01 | Wagner (316) | 63 | 85 | Seton Hall (53) | Final | L | -22 |
| 7 | 2021-12-04 | Wagner (316) | 78 | 49 | Stony Brook (213) | Final | W | 29 |
| 8 | 2021-12-08 | Wagner (75) | 54 | 74 | Penn State (129) | Final | L | -20 |
| 9 | 2021-12-16 | Immaculata | 46 | 104 | Wagner (316) | Final | W | 58 |
| 10 | 2021-12-20 | Delaware State (361) | 51 | 93 | Wagner (316) | Final | W | 42 |
| 11 | 2021-12-23 | Wagner (316) | 63 | 50 | Fairfield (204) | Final | W | 13 |
| 12 | 2021-12-29 | Wagner (316) | 72 | 64 | Saint Francis (354) | Final | W | 8 |
| 13 | 2021-12-29 | Wagner (74) | 72 | 64 | St. Francis (PA) (301) | Final | W | 8 |
| 14 | 2021-12-31 | Wagner (316) | 2 | 0 | Mount St Mary's (257) | Forfeit | W | 2 |
| 15 | 2022-01-06 | Bryant (349) | 81 | 84 | Wagner (316) | Final/OT | W | 3 |
| 16 | 2022-01-08 | Sacred Heart (270) | 0 | 2 | Wagner (316) | Forfeit | W | 2 |
| 17 | 2022-01-15 | St. Francis (NY) | 76 | 81 | Wagner (316) | Final | W | 5 |
| 18 | 2022-01-17 | Fairleigh Dickinson (346) | 64 | 95 | Wagner (82) | Final | W | 31 |
| 19 | 2022-01-21 | Wagner (82) | 92 | 85 | Long Island (273) | Final (OT) | W | 7 |
| 20 | 2022-01-23 | Wagner (72) | 71 | 57 | Merrimack (295) | Final | W | 14 |
| 21 | 2022-01-27 | St. Francis (PA) (317) | 54 | 69 | Wagner (72) | Final | W | 15 |
| 22 | 2022-01-30 | Wagner (70) | 72 | 69 | St. Francis (NY) (333) | Final | W | 3 |
| 23 | 2022-02-03 | Wagner (316) | 54 | 52 | Central Connecticut State (258) | Final | W | 2 |
| 24 | 2022-02-05 | Long Island (175) | 64 | 79 | Wagner (316) | Final | W | 15 |
| 25 | 2022-02-10 | Mount St Mary's (257) | 57 | 69 | Wagner (316) | Final | W | 12 |
| 26 | 2022-02-12 | Merrimack (134) | 80 | 65 | Wagner (316) | Final/OT | L | -15 |
| 27 | 2022-02-17 | Wagner (316) | 76 | 67 | Sacred Heart (270) | Final | W | 9 |
| 28 | 2022-02-19 | Central Connecticut State (344) | 68 | 78 | Wagner (94) | Final | W | 10 |
| 29 | 2022-02-24 | Wagner (96) | 86 | 88 | Fairleigh Dickinson (354) | Final | L | -2 |
| 30 | 2022-02-26 | Wagner (96) | 70 | 78 | Bryant (204) | Final | L | -8 |
| 31 | 2022-03-02 | St. Francis (PA) (334) | 53 | 82 | Wagner (123) | Final | W | 29 |
| 32 | 2022-03-05 | Long Island (247) | 62 | 82 | Wagner (123) | Final | W | 20 |
| 33 | 2022-03-08 | Wagner (116) | 43 | 70 | Bryant (189) | Final | L | -27 |