Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Salve Regina | 59 | 89 | Brown | Final | W | 30 |
| 2 | 2021-11-12 | Brown (295) | 87 | 94 | North Carolina (22) | Final | L | -7 |
| 3 | 2021-11-14 | Central Connecticut State (258) | 57 | 75 | Brown (295) | Final | W | 18 |
| 4 | 2021-11-16 | Johnson & Wales (RI) | 47 | 98 | Brown (178) | Final | W | 51 |
| 5 | 2021-11-19 | Brown (295) | 57 | 78 | Creighton (78) | Final | L | -21 |
| 6 | 2021-11-20 | Bradley (113) | 62 | 65 | Brown (295) | Final | W | 3 |
| 7 | 2021-11-22 | Brown (295) | 52 | 54 | Colorado (73) | Final | L | -2 |
| 8 | 2021-11-26 | Bryant (349) | 65 | 59 | Brown (295) | Final | L | -6 |
| 9 | 2021-11-28 | Brown (211) | 72 | 61 | Quinnipiac (250) | Final | W | 11 |
| 10 | 2021-12-01 | Brown (295) | 73 | 63 | UMass-Lowell (319) | Final | W | 10 |
| 11 | 2021-12-05 | Sacred Heart (282) | 66 | 79 | Brown (211) | Final | W | 13 |
| 12 | 2021-12-07 | Brown (295) | 76 | 56 | Merrimack (134) | Final | W | 20 |
| 13 | 2021-12-10 | Vermont (120) | 70 | 65 | Brown (151) | Final | L | -5 |
| 14 | 2021-12-22 | Brown (295) | 0 | 0 | Rhode Island (145) | Cancelled | - | - |
| 15 | 2021-12-27 | Brown (295) | 62 | 93 | Syracuse (84) | Final | L | -31 |
| 16 | 2021-12-30 | Brown (295) | 67 | 81 | Maryland (114) | Final | L | -14 |
| 17 | 2022-01-02 | Brown (295) | 73 | 77 | Penn (131) | Final | L | -4 |
| 18 | 2022-01-07 | Brown (295) | 84 | 73 | Harvard (181) | Final | W | 11 |
| 19 | 2022-01-08 | Brown (295) | 46 | 58 | Dartmouth (256) | Final | L | -12 |
| 20 | 2022-01-15 | Brown (295) | 74 | 76 | Princeton (271) | Final | L | -2 |
| 21 | 2022-01-17 | Yale (159) | 66 | 63 | Brown (205) | Final | L | -3 |
| 22 | 2022-01-22 | Brown (295) | 93 | 74 | Columbia (193) | Final | W | 19 |
| 23 | 2022-01-30 | Cornell (174) | 74 | 72 | Brown (221) | Final | L | -2 |
| 24 | 2022-02-04 | Harvard (235) | 65 | 50 | Brown (221) | Final | L | -15 |
| 25 | 2022-02-05 | Dartmouth (256) | 60 | 62 | Brown (295) | Final | W | 2 |
| 26 | 2022-02-12 | Brown (295) | 81 | 80 | Cornell (187) | Final | W | 1 |
| 27 | 2022-02-18 | Princeton (109) | 69 | 50 | Brown (213) | Final | L | -19 |
| 28 | 2022-02-19 | Penn (192) | 89 | 88 | Brown (213) | Final | L | -1 |
| 29 | 2022-02-26 | Columbia (350) | 74 | 81 | Brown (226) | Final | W | 7 |
| 30 | 2022-03-05 | Brown (220) | 65 | 74 | Yale (143) | Final | L | -9 |