Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-10 | Regent | 54 | 118 | Howard (333) | Final | L | -64 |
| 2 | 2021-11-11 | Regent | 24 | 85 | Liberty (86) | Final | L | -61 |
| 3 | 2021-11-13 | Regent | 56 | 70 | Hampton (312) | Final | L | -14 |
| 4 | 2021-11-16 | Regent | 30 | 84 | Delaware State (358) | Final | L | -54 |
| 5 | 2021-11-23 | Regent | 20 | 95 | Norfolk State (137) | Final | L | -75 |
| 6 | 2021-12-16 | Regent | 53 | 110 | Coastal Carolina (188) | Final | L | -57 |