Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-05 | New Mexico Highlands | 72 | 101 | New Mexico (296) | Final | W | 29 |
| 2 | 2021-11-10 | Florida Atlantic (196) | 92 | 99 | New Mexico (296) | Final | W | 7 |
| 3 | 2021-11-13 | New Mexico (296) | 76 | 87 | Colorado (23) | Final | L | -11 |
| 4 | 2021-11-15 | Grambling (319) | 61 | 86 | New Mexico (172) | Final | W | 25 |
| 5 | 2021-11-20 | Montana State (197) | 78 | 81 | New Mexico (49) | Final | W | 3 |
| 6 | 2021-11-22 | Western New Mexico | 63 | 88 | New Mexico (49) | Final | W | 25 |
| 7 | 2021-11-25 | UAB (115) | 86 | 73 | New Mexico (49) | Final | L | -13 |
| 8 | 2021-11-26 | Towson (152) | 73 | 58 | New Mexico (49) | Final | L | -15 |
| 9 | 2021-11-30 | New Mexico (177) | 101 | 94 | New Mexico State (62) | Final | W | 7 |
| 10 | 2021-12-06 | New Mexico State (87) | 78 | 76 | New Mexico (133) | Final (OT) | L | -2 |
| 11 | 2021-12-09 | Denver (333) | 67 | 87 | New Mexico (133) | Final | W | 20 |
| 12 | 2021-12-12 | UTEP (274) | 77 | 69 | New Mexico (49) | Final | L | -8 |
| 13 | 2021-12-19 | SMU (45) | 90 | 72 | New Mexico (49) | Final | L | -18 |
| 14 | 2021-12-21 | Norfolk State (322) | 54 | 68 | New Mexico (49) | Final | W | 14 |
| 15 | 2021-12-28 | Colorado State (85) | 0 | 0 | New Mexico (49) | Postponed | - | - |
| 16 | 2022-01-01 | New Mexico (49) | 70 | 79 | Nevada (67) | Final | L | -9 |
| 17 | 2022-01-08 | Utah State (25) | 90 | 87 | New Mexico (49) | Final/OT | L | -3 |
| 18 | 2022-01-11 | New Mexico (49) | 56 | 85 | UNLV (105) | Final | L | -29 |
| 19 | 2022-01-15 | Boise State (62) | 71 | 63 | New Mexico (49) | Final | L | -8 |
| 20 | 2022-01-19 | New Mexico (49) | 74 | 80 | Colorado State (85) | Final | L | -6 |
| 21 | 2022-01-22 | New Mexico (49) | 91 | 93 | Wyoming (103) | Final | L | -2 |
| 22 | 2022-01-25 | Fresno State (84) | 65 | 60 | New Mexico (180) | Final | L | -5 |
| 23 | 2022-01-28 | San Jose State (214) | 70 | 86 | New Mexico (180) | Final | W | 16 |
| 24 | 2022-01-31 | New Mexico (173) | 47 | 72 | San Diego State (48) | Final | L | -25 |
| 25 | 2022-02-05 | New Mexico (49) | 91 | 77 | Air Force (347) | Final | W | 14 |
| 26 | 2022-02-11 | Northern New Mexico | 46 | 78 | New Mexico (49) | Final | W | 32 |
| 27 | 2022-02-15 | Wyoming (21) | 66 | 75 | New Mexico (165) | Final | W | 9 |
| 28 | 2022-02-17 | Colorado State (85) | 83 | 68 | New Mexico (49) | Final | L | -15 |
| 29 | 2022-02-20 | New Mexico (164) | 55 | 71 | San Jose State (241) | Final | L | -16 |
| 30 | 2022-02-22 | New Mexico (164) | 56 | 81 | Utah State (87) | Final | L | -25 |
| 31 | 2022-02-26 | Air Force (213) | 65 | 69 | New Mexico (164) | Final | W | 4 |
| 32 | 2022-02-28 | New Mexico (160) | 68 | 71 | Fresno State (87) | Final | L | -3 |
| 33 | 2022-03-05 | UNLV (84) | 67 | 76 | New Mexico (160) | Final | W | 9 |
| 34 | 2022-03-09 | New Mexico (154) | 72 | 79 | Nevada (127) | Final | L | -7 |