Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-03 | Cal State-Stanislas | 48 | 86 | Fresno State (180) | Final | W | 38 |
| 2 | 2021-11-09 | Fresno Pacific | 54 | 74 | Fresno State (180) | Final | W | 20 |
| 3 | 2021-11-12 | Long Island (175) | 60 | 84 | Fresno State (153) | Final | W | 24 |
| 4 | 2021-11-15 | Idaho (276) | 62 | 69 | Fresno State (126) | Final | W | 7 |
| 5 | 2021-11-23 | Fresno State (153) | 70 | 63 | Pepperdine (283) | Final | W | 7 |
| 6 | 2021-11-23 | Pepperdine (228) | 63 | 70 | Fresno State (133) | Final | W | 7 |
| 7 | 2021-11-25 | Fresno State (153) | 59 | 52 | Santa Clara (42) | Final | W | 7 |
| 8 | 2021-11-28 | Fresno State (118) | 57 | 65 | California (148) | Final | L | -8 |
| 9 | 2021-12-01 | San Diego (246) | 43 | 63 | Fresno State (153) | Final | W | 20 |
| 10 | 2021-12-04 | Cal State-Northridge (180) | 43 | 61 | Fresno State (153) | Final | W | 18 |
| 11 | 2021-12-08 | Fresno State (93) | 63 | 71 | San Francisco (8) | Final | L | -8 |
| 12 | 2021-12-11 | UC-Irvine (119) | 55 | 63 | Fresno State (153) | Final | W | 8 |
| 13 | 2021-12-17 | Cal Poly (238) | 48 | 83 | Fresno State (153) | Final | W | 35 |
| 14 | 2021-12-21 | Fresno State (153) | 50 | 55 | Utah (130) | Final | L | -5 |
| 15 | 2021-12-23 | Fresno State (153) | 69 | 43 | Weber State (235) | Final | W | 26 |
| 16 | 2021-12-28 | Fresno State (153) | 55 | 65 | Boise State (62) | Final | L | -10 |
| 17 | 2022-01-01 | Air Force (347) | 0 | 0 | Fresno State (153) | Canceled | - | - |
| 18 | 2022-01-05 | Fresno State (153) | 0 | 0 | San Diego State (48) | Postponed | - | - |
| 19 | 2022-01-08 | Wyoming (103) | 0 | 0 | Fresno State (153) | Postponed | - | - |
| 20 | 2022-01-11 | San Jose State (229) | 59 | 79 | Fresno State (153) | Final | W | 20 |
| 21 | 2022-01-14 | Fresno State (95) | 73 | 68 | UNLV (121) | Final | W | 5 |
| 22 | 2022-01-18 | Utah State (25) | 54 | 61 | Fresno State (153) | Final | W | 7 |
| 23 | 2022-01-21 | Fresno State (81) | 73 | 77 | Nevada (120) | Final | L | -4 |
| 24 | 2022-01-25 | Fresno State (84) | 65 | 60 | New Mexico (180) | Final | W | 5 |
| 25 | 2022-01-28 | Boise State (52) | 68 | 63 | Fresno State (84) | Final | L | -5 |
| 26 | 2022-02-01 | Fresno State (84) | 73 | 43 | San Jose State (238) | Final | W | 30 |
| 27 | 2022-02-04 | Nevada (114) | 56 | 73 | Fresno State (84) | Final | W | 17 |
| 28 | 2022-02-06 | Wyoming (103) | 61 | 59 | Fresno State (153) | Final | L | -2 |
| 29 | 2022-02-11 | Fresno State (153) | 50 | 65 | Colorado State (85) | Final | L | -15 |
| 30 | 2022-02-16 | UNLV (101) | 60 | 57 | Fresno State (86) | Final | L | -3 |
| 31 | 2022-02-19 | San Diego State (41) | 61 | 44 | Fresno State (86) | Final | L | -17 |
| 32 | 2022-02-22 | Fresno State (92) | 65 | 40 | Air Force (213) | Final | W | 25 |
| 33 | 2022-02-28 | New Mexico (160) | 68 | 71 | Fresno State (87) | Final | W | 3 |
| 34 | 2022-03-03 | Fresno State (87) | 64 | 65 | San Diego State (36) | Final | L | -1 |
| 35 | 2022-03-05 | Fresno State (87) | 64 | 68 | Wyoming (34) | Final | L | -4 |
| 36 | 2022-03-09 | San Jose State (258) | 67 | 69 | Fresno State (91) | Final | W | 2 |
| 37 | 2022-03-10 | Fresno State (91) | 46 | 53 | San Diego State (28) | Final | L | -7 |
| 38 | 2022-03-17 | Eastern Washington (225) | 74 | 83 | Fresno State (91) | Final | W | 9 |
| 39 | 2022-03-23 | Youngstown State (249) | 71 | 80 | Fresno State (91) | Final | W | 9 |
| 40 | 2022-03-28 | Southern Utah (177) | 48 | 67 | Fresno State (91) | Final | W | 19 |
| 41 | 2022-04-01 | Fresno State (91) | 85 | 74 | Coastal Carolina (172) | Final | W | 11 |