Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-01 | Dominican (CA) | 55 | 90 | Nevada (91) | Final | W | 35 |
| 2 | 2021-11-09 | Eastern Washington (119) | 76 | 91 | Nevada (91) | Final | W | 15 |
| 3 | 2021-11-12 | San Diego (246) | 75 | 68 | Nevada (67) | Final | L | -7 |
| 4 | 2021-11-13 | San Diego (251) | 75 | 68 | Nevada (91) | Final | L | -7 |
| 5 | 2021-11-16 | Nevada (162) | 74 | 96 | Santa Clara (55) | Final | L | -22 |
| 6 | 2021-11-18 | Nevada (162) | 70 | 73 | San Francisco (19) | Final | L | -3 |
| 7 | 2021-11-22 | South Dakota State (268) | 102 | 75 | Nevada (67) | Final | L | -27 |
| 8 | 2021-11-23 | Nevada (223) | 88 | 69 | George Mason (34) | Final | W | 19 |
| 9 | 2021-11-24 | Nevada (67) | 81 | 62 | Washington (72) | Final | W | 19 |
| 10 | 2021-11-30 | Pepperdine (280) | 66 | 79 | Nevada (147) | Final | W | 13 |
| 11 | 2021-12-04 | Nevada | 0 | 0 | North Texas | Cancelled | - | - |
| 12 | 2021-12-07 | Nevada (67) | 0 | 0 | Texas-Arlington (162) | Cancelled | - | - |
| 13 | 2021-12-15 | Minnesota-Duluth | 62 | 98 | Nevada (143) | Final | W | 36 |
| 14 | 2021-12-18 | Loyola Marymount (184) | 63 | 68 | Nevada (67) | Final | W | 5 |
| 15 | 2021-12-21 | Grand Canyon (74) | 0 | 0 | Nevada (67) | Cancelled | - | - |
| 16 | 2021-12-29 | Nevada (67) | 61 | 88 | Kansas (19) | Final | L | -27 |
| 17 | 2022-01-01 | New Mexico (49) | 70 | 79 | Nevada (67) | Final | W | 9 |
| 18 | 2022-01-04 | Wyoming (103) | 0 | 0 | Nevada (67) | Postponed | - | - |
| 19 | 2022-01-12 | Boise State (63) | 85 | 70 | Nevada (125) | Final | L | -15 |
| 20 | 2022-01-15 | Nevada (67) | 75 | 68 | Air Force (347) | Final | W | 7 |
| 21 | 2022-01-17 | Wyoming (37) | 77 | 67 | Nevada (120) | Final | L | -10 |
| 22 | 2022-01-21 | Fresno State (81) | 73 | 77 | Nevada (120) | Final | W | 4 |
| 23 | 2022-01-25 | Nevada (111) | 66 | 77 | Colorado State (18) | Final | L | -11 |
| 24 | 2022-01-29 | Utah State (25) | 78 | 49 | Nevada (67) | Final | L | -29 |
| 25 | 2022-02-01 | Nevada (114) | 58 | 69 | UNLV (105) | Final | L | -11 |
| 26 | 2022-02-04 | Nevada (114) | 56 | 73 | Fresno State (84) | Final | L | -17 |
| 27 | 2022-02-06 | Nevada (67) | 63 | 65 | San Diego State (48) | Final | L | -2 |
| 28 | 2022-02-08 | Colorado State (31) | 82 | 72 | Nevada (137) | Final | L | -10 |
| 29 | 2022-02-11 | Nevada (67) | 85 | 72 | Utah State (25) | Final | W | 13 |
| 30 | 2022-02-15 | San Jose State (251) | 72 | 81 | Nevada (126) | Final | W | 9 |
| 31 | 2022-02-17 | Nevada (67) | 90 | 60 | San Jose State (229) | Final | W | 30 |
| 32 | 2022-02-18 | Nevada (126) | 90 | 60 | San Jose State (251) | Final | W | 30 |
| 33 | 2022-02-22 | UNLV (85) | 62 | 54 | Nevada (121) | Final | L | -8 |
| 34 | 2022-02-26 | Nevada (121) | 61 | 74 | Wyoming (31) | Final | L | -13 |
| 35 | 2022-03-01 | Nevada (126) | 67 | 73 | Boise State (32) | Final | L | -6 |
| 36 | 2022-03-05 | San Diego State (36) | 79 | 78 | Nevada (126) | Final | L | -1 |
| 37 | 2022-03-09 | New Mexico (154) | 72 | 79 | Nevada (127) | Final | W | 7 |
| 38 | 2022-03-10 | Nevada (127) | 69 | 71 | Boise State (31) | Final | L | -2 |