Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Cal State-Northridge (262) | 49 | 89 | USC (16) | Final | L | -40 |
| 2 | 2021-11-13 | Cal State-Northridge (262) | 52 | 68 | Notre Dame (102) | Final | L | -16 |
| 3 | 2021-11-19 | Eastern Washington (242) | 67 | 64 | Cal State-Northridge (180) | Final/OT | L | -3 |
| 4 | 2021-11-20 | Utah Tech (186) | 73 | 79 | Cal State-Northridge (180) | Final | W | 6 |
| 5 | 2021-11-20 | Dixie State (164) | 73 | 79 | Cal State-Northridge (327) | Final | W | 6 |
| 6 | 2021-11-24 | St. Katherine | 62 | 71 | Cal State-Northridge (180) | Final | W | 9 |
| 7 | 2021-11-24 | St. Katherine | 62 | 71 | Cal State-Northridge (293) | Final | W | 9 |
| 8 | 2021-11-28 | Cal State-Northridge (240) | 56 | 52 | San Diego (182) | Final | W | 4 |
| 9 | 2021-12-04 | Cal State-Northridge (180) | 43 | 61 | Fresno State (153) | Final | L | -18 |
| 10 | 2021-12-07 | Boise State (62) | 74 | 48 | Cal State-Northridge (180) | Final | L | -26 |
| 11 | 2021-12-10 | Cal State-Northridge (260) | 54 | 68 | North Dakota State (209) | Final | L | -14 |
| 12 | 2021-12-18 | Portland State (192) | 66 | 69 | Cal State-Northridge (180) | Final | W | 3 |
| 13 | 2021-12-22 | Bethesda | 82 | 80 | Cal State-Northridge (180) | Final | L | -2 |
| 14 | 2021-12-30 | Cal State-Northridge (180) | 0 | 0 | UC-Irvine (119) | Cancelled | - | - |
| 15 | 2022-01-01 | Cal State-Northridge (180) | 64 | 72 | UC-San Diego (126) | Final | L | -8 |
| 16 | 2022-01-06 | Cal State-Bakersfield (333) | 0 | 0 | Cal State-Northridge (180) | Canceled | - | - |
| 17 | 2022-01-08 | Cal Poly (238) | 55 | 68 | Cal State-Northridge (180) | Final | W | 13 |
| 18 | 2022-01-13 | Cal State-Northridge (180) | 64 | 79 | Cal State-Fullerton (194) | Final | L | -15 |
| 19 | 2022-01-15 | Cal State-Northridge (180) | 55 | 71 | Long Beach State (278) | Final | L | -16 |
| 20 | 2022-01-20 | UC-Davis (170) | 64 | 47 | Cal State-Northridge (180) | Final | L | -17 |
| 21 | 2022-01-22 | UC-Riverside (292) | 77 | 67 | Cal State-Northridge (180) | Final | L | -10 |
| 22 | 2022-01-25 | UC-Santa Barbara (262) | 72 | 45 | Cal State-Northridge (320) | Final | L | -27 |
| 23 | 2022-01-27 | Cal State-Northridge (180) | 65 | 72 | Hawaii (109) | Final | L | -7 |
| 24 | 2022-01-28 | Cal State-Northridge (320) | 65 | 72 | Hawaii (171) | Final | L | -7 |
| 25 | 2022-02-03 | UC-San Diego (126) | 83 | 77 | Cal State-Northridge (180) | Final | L | -6 |
| 26 | 2022-02-05 | UC-Irvine (119) | 75 | 70 | Cal State-Northridge (180) | Final | L | -5 |
| 27 | 2022-02-10 | Cal State-Northridge (180) | 83 | 78 | Cal Poly (238) | Final/2OT | W | 5 |
| 28 | 2022-02-12 | Cal State-Northridge (180) | 71 | 65 | Cal State-Bakersfield (333) | Final | W | 6 |
| 29 | 2022-02-17 | Long Beach State (278) | 72 | 59 | Cal State-Northridge (180) | Final | L | -13 |
| 30 | 2022-02-19 | Cal State-Fullerton (183) | 81 | 73 | Cal State-Northridge (314) | Final | L | -8 |
| 31 | 2022-02-24 | Cal State-Northridge (317) | 57 | 79 | UC-Riverside (178) | Final | L | -22 |
| 32 | 2022-02-26 | Cal State-Northridge (317) | 49 | 68 | UC-Davis (233) | Final | L | -19 |
| 33 | 2022-03-01 | Cal State-Northridge (321) | 61 | 70 | UC-Santa Barbara (200) | Final | L | -9 |
| 34 | 2022-03-05 | Hawaii (181) | 84 | 62 | Cal State-Northridge (321) | Final | L | -22 |
| 35 | 2022-03-08 | Cal State-Bakersfield (305) | 58 | 45 | Cal State-Northridge (325) | Final | L | -13 |