Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-10-23 | Colorado State (52) | 0 | 0 | Denver (343) | Cancelled | - | - |
| 2 | 2021-10-31 | Adams State | 55 | 92 | Colorado State (52) | Final | W | 37 |
| 3 | 2021-11-09 | Oral Roberts (174) | 80 | 109 | Colorado State (52) | Final | W | 29 |
| 4 | 2021-11-12 | Arkansas-Pine Bluff (303) | 71 | 91 | Colorado State (85) | Final | W | 20 |
| 5 | 2021-11-14 | Peru State | 62 | 88 | Colorado State (85) | Final | W | 26 |
| 6 | 2021-11-19 | Bradley (113) | 60 | 66 | Colorado State (85) | Final | W | 6 |
| 7 | 2021-11-21 | Colorado State (40) | 95 | 81 | Creighton (78) | Final | W | 14 |
| 8 | 2021-11-22 | Colorado State (85) | 71 | 61 | Northeastern (300) | Final | W | 10 |
| 9 | 2021-11-27 | Northern Colorado (281) | 79 | 88 | Colorado State (40) | Final | W | 9 |
| 10 | 2021-12-01 | Little Rock (321) | 55 | 86 | Colorado State (85) | Final | W | 31 |
| 11 | 2021-12-04 | Saint Mary's (33) | 58 | 74 | Colorado State (85) | Final | W | 16 |
| 12 | 2021-12-11 | Mississippi State (100) | 63 | 66 | Colorado State (85) | Final | W | 3 |
| 13 | 2021-12-17 | Colorado State (9) | 0 | 0 | Tulsa (191) | Cancelled | - | - |
| 14 | 2021-12-18 | Colorado State (85) | 0 | 0 | Tulsa (55) | Cancelled | - | - |
| 15 | 2021-12-28 | Colorado State (85) | 0 | 0 | New Mexico (49) | Postponed | - | - |
| 16 | 2022-01-04 | Air Force (347) | 59 | 67 | Colorado State (85) | Final | W | 8 |
| 17 | 2022-01-07 | Colorado State (85) | 0 | 0 | Boise State (62) | Postponed | - | - |
| 18 | 2022-01-08 | Colorado State (85) | 49 | 79 | San Diego State (48) | Final | L | -30 |
| 19 | 2022-01-12 | Utah State (86) | 72 | 77 | Colorado State (30) | Final | W | 5 |
| 20 | 2022-01-15 | Colorado State (85) | 78 | 42 | San Jose State (229) | Final | W | 36 |
| 21 | 2022-01-19 | New Mexico (49) | 74 | 80 | Colorado State (85) | Final | W | 6 |
| 22 | 2022-01-22 | Colorado State (85) | 73 | 53 | Air Force (347) | Final | W | 20 |
| 23 | 2022-01-25 | Nevada (111) | 66 | 77 | Colorado State (18) | Final | W | 11 |
| 24 | 2022-01-28 | UNLV (112) | 88 | 74 | Colorado State (18) | Final | L | -14 |
| 25 | 2022-01-31 | Colorado State (28) | 78 | 84 | Wyoming (38) | Final (OT) | L | -6 |
| 26 | 2022-02-04 | San Diego State (48) | 57 | 58 | Colorado State (28) | Final | W | 1 |
| 27 | 2022-02-08 | Colorado State (31) | 82 | 72 | Nevada (137) | Final | W | 10 |
| 28 | 2022-02-11 | Fresno State (153) | 50 | 65 | Colorado State (85) | Final | W | 15 |
| 29 | 2022-02-13 | Colorado State (20) | 77 | 74 | Boise State (37) | Final (OT) | W | 3 |
| 30 | 2022-02-17 | Colorado State (85) | 83 | 68 | New Mexico (49) | Final | W | 15 |
| 31 | 2022-02-19 | Colorado State (20) | 51 | 72 | UNLV (101) | Final | L | -21 |
| 32 | 2022-02-23 | Wyoming (31) | 55 | 61 | Colorado State (25) | Final | W | 6 |
| 33 | 2022-02-26 | Colorado State (25) | 66 | 55 | Utah State (87) | Final | W | 11 |
| 34 | 2022-03-05 | Boise State (32) | 68 | 71 | Colorado State (24) | Final | W | 3 |
| 35 | 2022-03-10 | Utah State (83) | 51 | 53 | Colorado State (19) | Final | W | 2 |
| 36 | 2022-03-12 | San Diego State (28) | 63 | 58 | Colorado State (19) | Final | L | -5 |
| 37 | 2022-03-17 | Michigan (45) | 75 | 63 | Colorado State (21) | Final | L | -12 |