Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-05 | CS East Bay | 56 | 60 | San Jose State (325) | Final | W | 4 |
| 2 | 2021-11-11 | Cal State-Fullerton (257) | 76 | 78 | San Jose State (325) | Final | W | 2 |
| 3 | 2021-11-15 | San Jose State (116) | 62 | 76 | Stanford (188) | Final | L | -14 |
| 4 | 2021-11-18 | San Jose State (116) | 66 | 67 | California Baptist (130) | Final | L | -1 |
| 5 | 2021-11-20 | San Jose State (229) | 45 | 79 | Texas (41) | Final | L | -34 |
| 6 | 2021-11-23 | Northern Colorado (281) | 74 | 75 | San Jose State (242) | Final | W | 1 |
| 7 | 2021-11-30 | South Dakota (179) | 52 | 61 | San Jose State (221) | Final | W | 9 |
| 8 | 2021-12-03 | North Dakota (251) | 51 | 76 | San Jose State (229) | Final | W | 25 |
| 9 | 2021-12-06 | San Jose State (153) | 69 | 82 | Pepperdine (293) | Final | L | -13 |
| 10 | 2021-12-11 | Pacific (132) | 66 | 78 | San Jose State (229) | Final | W | 12 |
| 11 | 2021-12-17 | San Jose State (229) | 90 | 78 | Portland (210) | Final | W | 12 |
| 12 | 2021-12-21 | Santa Clara (42) | 79 | 57 | San Jose State (229) | Final | L | -22 |
| 13 | 2022-01-01 | San Jose State (229) | 0 | 0 | Utah State (25) | Postponed | - | - |
| 14 | 2022-01-05 | UNLV (105) | 0 | 0 | San Jose State (229) | Postponed | - | - |
| 15 | 2022-01-08 | Bethesda | 43 | 118 | San Jose State (229) | Final | W | 75 |
| 16 | 2022-01-11 | San Jose State (229) | 59 | 79 | Fresno State (153) | Final | L | -20 |
| 17 | 2022-01-15 | Colorado State (85) | 78 | 42 | San Jose State (229) | Final | L | -36 |
| 18 | 2022-01-17 | UNLV (113) | 81 | 56 | San Jose State (190) | Final | L | -25 |
| 19 | 2022-01-19 | San Jose State (229) | 69 | 84 | Wyoming (103) | Final | L | -15 |
| 20 | 2022-01-22 | San Jose State (229) | 62 | 70 | UNLV (105) | Final | L | -8 |
| 21 | 2022-01-25 | Air Force (185) | 63 | 53 | San Jose State (214) | Final | L | -10 |
| 22 | 2022-01-28 | San Jose State (214) | 70 | 86 | New Mexico (180) | Final | L | -16 |
| 23 | 2022-02-01 | Fresno State (84) | 73 | 43 | San Jose State (238) | Final | L | -30 |
| 24 | 2022-02-03 | San Jose State (229) | 62 | 78 | Utah State (25) | Final | L | -16 |
| 25 | 2022-02-05 | San Jose State (229) | 60 | 76 | Boise State (62) | Final | L | -16 |
| 26 | 2022-02-09 | San Diego State (48) | 72 | 62 | San Jose State (229) | Final | L | -10 |
| 27 | 2022-02-12 | Wyoming (103) | 74 | 52 | San Jose State (229) | Final | L | -22 |
| 28 | 2022-02-15 | San Jose State (251) | 72 | 81 | Nevada (126) | Final | L | -9 |
| 29 | 2022-02-17 | Nevada (67) | 90 | 60 | San Jose State (229) | Final | L | -30 |
| 30 | 2022-02-18 | Nevada (126) | 90 | 60 | San Jose State (251) | Final | L | -30 |
| 31 | 2022-02-20 | New Mexico (164) | 55 | 71 | San Jose State (241) | Final | W | 16 |
| 32 | 2022-02-25 | San Jose State (241) | 52 | 77 | San Diego State (34) | Final | L | -25 |
| 33 | 2022-03-01 | San Jose State (248) | 54 | 58 | Air Force (223) | Final | L | -4 |
| 34 | 2022-03-04 | Utah State (86) | 75 | 52 | San Jose State (248) | Final | L | -23 |
| 35 | 2022-03-09 | San Jose State (258) | 67 | 69 | Fresno State (91) | Final | L | -2 |