Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-10-23 | Colorado State (52) | 0 | 0 | Denver (343) | Cancelled | - | - |
| 2 | 2021-10-31 | Nebraska-Kearney | 0 | 0 | Denver (343) | Cancelled | - | - |
| 3 | 2021-11-09 | Regis | 65 | 68 | Denver (343) | Final | W | 3 |
| 4 | 2021-11-12 | Ottawa (AZ) | 72 | 71 | Denver (253) | Final | L | -1 |
| 5 | 2021-11-15 | IUPUI (335) | 47 | 63 | Denver (357) | Final | W | 16 |
| 6 | 2021-11-16 | Denver (357) | 64 | 78 | UTSA (272) | Final | L | -14 |
| 7 | 2021-11-17 | Denver (253) | 67 | 69 | Texas A&M-Corpus Christi (208) | Final | L | -2 |
| 8 | 2021-11-21 | Houston Baptist (322) | 61 | 74 | Denver (349) | Final | W | 13 |
| 9 | 2021-11-24 | Denver (253) | 65 | 66 | Air Force (347) | Final | L | -1 |
| 10 | 2021-11-27 | Denver (349) | 68 | 77 | Utah Valley (134) | Final (OT) | L | -9 |
| 11 | 2021-12-02 | Denver (342) | 64 | 77 | Wyoming (32) | Final | L | -13 |
| 12 | 2021-12-05 | Denver (342) | 58 | 71 | Texas State (129) | Final | L | -13 |
| 13 | 2021-12-09 | Denver (333) | 67 | 87 | New Mexico (133) | Final | L | -20 |
| 14 | 2021-12-11 | Denver (253) | 62 | 82 | Utah Tech (186) | Final | L | -20 |
| 15 | 2021-12-11 | Denver (333) | 62 | 82 | Dixie State (257) | Final | L | -20 |
| 16 | 2021-12-15 | UC-San Diego (126) | 56 | 64 | Denver (253) | Final | W | 8 |
| 17 | 2021-12-20 | Western Illinois (362) | 84 | 80 | Denver (253) | Final/OT | L | -4 |
| 18 | 2021-12-22 | St. Thomas (137) | 74 | 75 | Denver (253) | Final | W | 1 |
| 19 | 2021-12-30 | Denver (253) | 66 | 83 | Oral Roberts (327) | Final | L | -17 |
| 20 | 2022-01-01 | Denver (253) | 0 | 0 | UMKC (364) | Postponed | - | - |
| 21 | 2022-01-08 | North Dakota (251) | 74 | 93 | Denver (253) | Final | W | 19 |
| 22 | 2022-01-10 | North Dakota State (169) | 87 | 69 | Denver (315) | Final | L | -18 |
| 23 | 2022-01-13 | Denver (253) | 71 | 80 | South Dakota (275) | Final | L | -9 |
| 24 | 2022-01-15 | Denver (253) | 62 | 80 | South Dakota State (268) | Final | L | -18 |
| 25 | 2022-01-17 | Denver (327) | 63 | 55 | UMKC (219) | Final | W | 8 |
| 26 | 2022-01-22 | Nebraska-Omaha (272) | 63 | 94 | Denver (253) | Final | W | 31 |
| 27 | 2022-01-27 | UMKC (364) | 72 | 61 | Denver (253) | Final | L | -11 |
| 28 | 2022-01-29 | Oral Roberts (327) | 89 | 80 | Denver (253) | Final | L | -9 |
| 29 | 2022-02-03 | Denver (253) | 81 | 79 | North Dakota (251) | Final/OT | W | 2 |
| 30 | 2022-02-05 | Denver (253) | 65 | 73 | North Dakota State (117) | Final | L | -8 |
| 31 | 2022-02-10 | South Dakota State (268) | 84 | 61 | Denver (253) | Final | L | -23 |
| 32 | 2022-02-12 | South Dakota (275) | 84 | 76 | Denver (253) | Final | L | -8 |
| 33 | 2022-02-17 | Denver (253) | 69 | 72 | Nebraska-Omaha (272) | Final | L | -3 |
| 34 | 2022-02-24 | Denver (320) | 91 | 80 | St. Thomas (313) | Final | W | 11 |
| 35 | 2022-02-26 | Denver (320) | 83 | 77 | Western Illinois (232) | Final | W | 6 |
| 36 | 2022-03-05 | Denver (307) | 62 | 82 | North Dakota State (147) | Final | L | -20 |