Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | UMKC (272) | 56 | 71 | Minnesota (64) | Final | L | -15 |
| 2 | 2021-11-12 | UMKC (364) | 57 | 89 | Iowa (28) | Final | L | -32 |
| 3 | 2021-11-15 | UMKC (288) | 80 | 66 | Missouri (128) | Final | W | 14 |
| 4 | 2021-11-17 | Kansas Christian | 36 | 99 | UMKC (364) | Final | W | 63 |
| 5 | 2021-11-22 | UMKC (364) | 74 | 58 | Idaho State (289) | Final | W | 16 |
| 6 | 2021-11-27 | UMKC (124) | 62 | 70 | Morehead State (279) | Final | L | -8 |
| 7 | 2021-11-28 | UMKC (223) | 55 | 66 | Arkansas State (260) | Final | L | -11 |
| 8 | 2021-12-04 | Calvary | 32 | 94 | UMKC (364) | Final | W | 62 |
| 9 | 2021-12-10 | Green Bay (300) | 55 | 64 | UMKC (201) | Final | W | 9 |
| 10 | 2021-12-12 | UMKC (364) | 56 | 60 | SIU-Edwardsville (248) | Final | L | -4 |
| 11 | 2021-12-20 | UMKC (364) | 57 | 89 | South Dakota State (268) | Final | L | -32 |
| 12 | 2021-12-22 | UMKC (364) | 68 | 57 | South Dakota (275) | Final | W | 11 |
| 13 | 2021-12-30 | Nebraska-Omaha (272) | 0 | 0 | UMKC (364) | Postponed | - | - |
| 14 | 2022-01-01 | Denver (253) | 0 | 0 | UMKC (364) | Postponed | - | - |
| 15 | 2022-01-06 | UMKC (364) | 0 | 0 | Western Illinois (362) | Postponed | - | - |
| 16 | 2022-01-08 | UMKC (364) | 0 | 0 | St. Thomas (137) | Postponed | - | - |
| 17 | 2022-01-10 | Nebraska-Omaha (337) | 61 | 64 | UMKC (213) | Final | W | 3 |
| 18 | 2022-01-11 | Baptist Bible | 57 | 98 | UMKC (213) | Final | W | 41 |
| 19 | 2022-01-15 | Oral Roberts (327) | 84 | 72 | UMKC (364) | Final | L | -12 |
| 20 | 2022-01-17 | Denver (327) | 63 | 55 | UMKC (219) | Final | L | -8 |
| 21 | 2022-01-20 | North Dakota State (117) | 77 | 80 | UMKC (364) | Final | W | 3 |
| 22 | 2022-01-22 | North Dakota (251) | 74 | 79 | UMKC (364) | Final | W | 5 |
| 23 | 2022-01-24 | Spurgeon | 44 | 111 | UMKC (364) | Final | W | 67 |
| 24 | 2022-01-27 | UMKC (364) | 72 | 61 | Denver (253) | Final | W | 11 |
| 25 | 2022-01-29 | UMKC (364) | 68 | 69 | Nebraska-Omaha (272) | Final | L | -1 |
| 26 | 2022-01-31 | UMKC (226) | 83 | 75 | Western Illinois (204) | Final | W | 8 |
| 27 | 2022-02-03 | St. Thomas (137) | 72 | 81 | UMKC (364) | Final | W | 9 |
| 28 | 2022-02-05 | Western Illinois (362) | 82 | 91 | UMKC (364) | Final | W | 9 |
| 29 | 2022-02-08 | UMKC (199) | 76 | 67 | St. Thomas (294) | Final | W | 9 |
| 30 | 2022-02-12 | UMKC (364) | 86 | 91 | Oral Roberts (327) | Final | L | -5 |
| 31 | 2022-02-17 | UMKC (364) | 80 | 65 | North Dakota (251) | Final | W | 15 |
| 32 | 2022-02-19 | UMKC (203) | 85 | 71 | North Dakota State (148) | Final | W | 14 |
| 33 | 2022-02-24 | South Dakota (190) | 63 | 72 | UMKC (193) | Final | W | 9 |
| 34 | 2022-02-26 | South Dakota State (52) | 86 | 75 | UMKC (193) | Final | L | -11 |
| 35 | 2022-03-06 | South Dakota (181) | 74 | 61 | UMKC (198) | Final | L | -13 |