Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Oral Roberts (174) | 80 | 109 | Colorado State (52) | Final | L | -29 |
| 2 | 2021-11-12 | Southwestern Christian | 50 | 121 | Oral Roberts (174) | Final | W | 71 |
| 3 | 2021-11-18 | Haskell | 46 | 89 | Oral Roberts (209) | Final | W | 43 |
| 4 | 2021-11-20 | Oral Roberts (327) | 67 | 70 | Central Arkansas (143) | Final | L | -3 |
| 5 | 2021-11-23 | Rogers State | 31 | 91 | Oral Roberts (256) | Final | W | 60 |
| 6 | 2021-11-26 | Oklahoma State (57) | 78 | 77 | Oral Roberts (327) | Final/OT | L | -1 |
| 7 | 2021-11-29 | Tulsa (108) | 80 | 87 | Oral Roberts (258) | Final | W | 7 |
| 8 | 2021-12-02 | Oral Roberts (258) | 63 | 71 | TCU (85) | Final | L | -8 |
| 9 | 2021-12-04 | Oral Roberts (327) | 85 | 67 | Houston Christian (305) | Final | W | 18 |
| 10 | 2021-12-04 | Oral Roberts (258) | 85 | 67 | Houston Baptist (321) | Final | W | 18 |
| 11 | 2021-12-11 | Oral Roberts (327) | 60 | 69 | Missouri State (224) | Final | L | -9 |
| 12 | 2021-12-16 | Texas-Arlington (162) | 62 | 71 | Oral Roberts (327) | Final | W | 9 |
| 13 | 2021-12-20 | Oral Roberts (327) | 82 | 73 | South Dakota (275) | Final | W | 9 |
| 14 | 2021-12-22 | Oral Roberts (327) | 76 | 82 | South Dakota State (268) | Final | L | -6 |
| 15 | 2021-12-30 | Denver (253) | 66 | 83 | Oral Roberts (327) | Final | W | 17 |
| 16 | 2022-01-01 | Nebraska-Omaha (272) | 62 | 107 | Oral Roberts (327) | Final | W | 45 |
| 17 | 2022-01-06 | Oral Roberts (327) | 81 | 66 | St. Thomas (137) | Final | W | 15 |
| 18 | 2022-01-08 | Oral Roberts (327) | 87 | 86 | Western Illinois (362) | Final | W | 1 |
| 19 | 2022-01-15 | Oral Roberts (327) | 84 | 72 | UMKC (364) | Final | W | 12 |
| 20 | 2022-01-20 | North Dakota (251) | 76 | 80 | Oral Roberts (327) | Final | W | 4 |
| 21 | 2022-01-22 | North Dakota State (117) | 72 | 71 | Oral Roberts (327) | Final | L | -1 |
| 22 | 2022-01-27 | Oral Roberts (327) | 100 | 88 | Nebraska-Omaha (272) | Final | W | 12 |
| 23 | 2022-01-29 | Oral Roberts (327) | 89 | 80 | Denver (253) | Final | W | 9 |
| 24 | 2022-02-03 | Western Illinois (362) | 90 | 85 | Oral Roberts (327) | Final | L | -5 |
| 25 | 2022-02-05 | St. Thomas (137) | 66 | 88 | Oral Roberts (327) | Final | W | 22 |
| 26 | 2022-02-12 | UMKC (364) | 86 | 91 | Oral Roberts (327) | Final | W | 5 |
| 27 | 2022-02-17 | Oral Roberts (327) | 59 | 77 | North Dakota State (117) | Final | L | -18 |
| 28 | 2022-02-19 | Oral Roberts (135) | 87 | 73 | North Dakota (342) | Final | W | 14 |
| 29 | 2022-02-24 | South Dakota State (52) | 106 | 102 | Oral Roberts (142) | Final | L | -4 |
| 30 | 2022-02-26 | South Dakota (190) | 92 | 87 | Oral Roberts (142) | Final | L | -5 |
| 31 | 2022-03-06 | Western Illinois (235) | 68 | 80 | Oral Roberts (151) | Final | W | 12 |
| 32 | 2022-03-07 | Oral Roberts (151) | 72 | 92 | North Dakota State (144) | Final | L | -20 |