Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-01 | Mayville St | 64 | 68 | North Dakota (297) | Final | W | 4 |
| 2 | 2021-11-09 | Milwaukee (238) | 75 | 60 | North Dakota (297) | Final | L | -15 |
| 3 | 2021-11-15 | Montana (229) | 77 | 79 | North Dakota (294) | Final | W | 2 |
| 4 | 2021-11-19 | Troy (127) | 72 | 74 | North Dakota (251) | Final | W | 2 |
| 5 | 2021-11-20 | North Dakota (251) | 79 | 98 | Florida Atlantic (128) | Final | L | -19 |
| 6 | 2021-11-21 | Tennessee-Martin (270) | 77 | 72 | North Dakota (260) | Final | L | -5 |
| 7 | 2021-11-24 | North Dakota (251) | 56 | 65 | Florida International (214) | Final | L | -9 |
| 8 | 2021-11-28 | North Dakota (310) | 42 | 84 | Kansas State (145) | Final | L | -42 |
| 9 | 2021-11-30 | Presentation | 55 | 72 | North Dakota (310) | Final | W | 17 |
| 10 | 2021-12-03 | North Dakota (251) | 51 | 76 | San Jose State (229) | Final | L | -25 |
| 11 | 2021-12-07 | North Dakota (251) | 71 | 89 | California Baptist (97) | Final | L | -18 |
| 12 | 2021-12-11 | Eastern Washington (242) | 76 | 60 | North Dakota (251) | Final | L | -16 |
| 13 | 2021-12-14 | North Central | 65 | 110 | North Dakota (251) | Final | W | 45 |
| 14 | 2021-12-18 | Dixie State (241) | 78 | 69 | North Dakota (328) | Final | L | -9 |
| 15 | 2021-12-22 | North Dakota (251) | 76 | 86 | North Dakota State (117) | Final | L | -10 |
| 16 | 2021-12-30 | South Dakota (275) | 0 | 0 | North Dakota (251) | Postponed | - | - |
| 17 | 2022-01-01 | South Dakota State (268) | 0 | 0 | North Dakota (251) | Postponed | - | - |
| 18 | 2022-01-06 | North Dakota (251) | 82 | 98 | Nebraska-Omaha (272) | Final | L | -16 |
| 19 | 2022-01-08 | North Dakota (251) | 74 | 93 | Denver (253) | Final | L | -19 |
| 20 | 2022-01-10 | South Dakota (239) | 75 | 68 | North Dakota (345) | Final | L | -7 |
| 21 | 2022-01-13 | Western Illinois (362) | 73 | 68 | North Dakota (251) | Final | L | -5 |
| 22 | 2022-01-15 | St. Thomas (137) | 0 | 0 | North Dakota (251) | Postponed | - | - |
| 23 | 2022-01-20 | North Dakota (251) | 76 | 80 | Oral Roberts (327) | Final | L | -4 |
| 24 | 2022-01-22 | North Dakota (251) | 74 | 79 | UMKC (364) | Final | L | -5 |
| 25 | 2022-01-27 | North Dakota (251) | 61 | 96 | South Dakota State (268) | Final | L | -35 |
| 26 | 2022-01-29 | North Dakota (251) | 58 | 71 | South Dakota (275) | Final | L | -13 |
| 27 | 2022-01-31 | South Dakota State (62) | 70 | 64 | North Dakota (347) | Final | L | -6 |
| 28 | 2022-02-03 | Denver (253) | 81 | 79 | North Dakota (251) | Final/OT | L | -2 |
| 29 | 2022-02-05 | Nebraska-Omaha (272) | 85 | 92 | North Dakota (251) | Final | W | 7 |
| 30 | 2022-02-10 | North Dakota (251) | 78 | 70 | St. Thomas (137) | Final | W | 8 |
| 31 | 2022-02-12 | North Dakota (251) | 68 | 70 | Western Illinois (362) | Final | L | -2 |
| 32 | 2022-02-17 | UMKC (364) | 80 | 65 | North Dakota (251) | Final | L | -15 |
| 33 | 2022-02-19 | Oral Roberts (135) | 87 | 73 | North Dakota (342) | Final | L | -14 |
| 34 | 2022-02-22 | St. Thomas (313) | 84 | 74 | North Dakota (344) | Final | L | -10 |
| 35 | 2022-02-26 | North Dakota State (149) | 79 | 53 | North Dakota (344) | Final | L | -26 |