Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Hastings | 57 | 67 | Nebraska-Omaha (334) | Final | W | 10 |
| 2 | 2021-11-13 | Nebraska-Omaha (334) | 69 | 73 | Ball State (191) | Final | L | -4 |
| 3 | 2021-11-17 | Nebraska-Omaha (272) | 64 | 79 | Kansas State (96) | Final | L | -15 |
| 4 | 2021-11-20 | Nebraska-Omaha (272) | 47 | 68 | Montana (230) | Final | L | -21 |
| 5 | 2021-11-23 | Nebraska-Omaha (345) | 40 | 96 | Texas Tech (73) | Final | L | -56 |
| 6 | 2021-11-26 | Nebraska-Omaha (272) | 40 | 97 | Purdue (8) | Final | L | -57 |
| 7 | 2021-11-30 | SIU-Edwardsville (304) | 75 | 65 | Nebraska-Omaha (345) | Final | L | -10 |
| 8 | 2021-12-04 | Eastern Washington (242) | 92 | 81 | Nebraska-Omaha (272) | Final | L | -11 |
| 9 | 2021-12-08 | Drake (110) | 78 | 70 | Nebraska-Omaha (350) | Final | L | -8 |
| 10 | 2021-12-11 | Texas A&M-Corpus Christi (208) | 87 | 73 | Nebraska-Omaha (272) | Final | L | -14 |
| 11 | 2021-12-15 | Nebraska-Omaha (272) | 71 | 84 | UNLV (105) | Final | L | -13 |
| 12 | 2021-12-20 | St. Thomas (137) | 80 | 73 | Nebraska-Omaha (272) | Final | L | -7 |
| 13 | 2021-12-22 | Western Illinois (362) | 78 | 84 | Nebraska-Omaha (272) | Final | W | 6 |
| 14 | 2021-12-30 | Nebraska-Omaha (272) | 0 | 0 | UMKC (364) | Postponed | - | - |
| 15 | 2022-01-01 | Nebraska-Omaha (272) | 62 | 107 | Oral Roberts (327) | Final | L | -45 |
| 16 | 2022-01-06 | North Dakota (251) | 82 | 98 | Nebraska-Omaha (272) | Final | W | 16 |
| 17 | 2022-01-08 | North Dakota State (117) | 71 | 67 | Nebraska-Omaha (272) | Final | L | -4 |
| 18 | 2022-01-10 | Nebraska-Omaha (337) | 61 | 64 | UMKC (213) | Final | L | -3 |
| 19 | 2022-01-13 | South Dakota State (268) | 95 | 86 | Nebraska-Omaha (272) | Final | L | -9 |
| 20 | 2022-01-15 | Nebraska-Omaha (272) | 70 | 105 | South Dakota (275) | Final | L | -35 |
| 21 | 2022-01-22 | Nebraska-Omaha (272) | 63 | 94 | Denver (253) | Final | L | -31 |
| 22 | 2022-01-27 | Oral Roberts (327) | 100 | 88 | Nebraska-Omaha (272) | Final | L | -12 |
| 23 | 2022-01-29 | UMKC (364) | 68 | 69 | Nebraska-Omaha (272) | Final | W | 1 |
| 24 | 2022-02-03 | Nebraska-Omaha (272) | 64 | 71 | North Dakota State (117) | Final | L | -7 |
| 25 | 2022-02-05 | Nebraska-Omaha (272) | 85 | 92 | North Dakota (251) | Final | L | -7 |
| 26 | 2022-02-10 | South Dakota (275) | 91 | 69 | Nebraska-Omaha (272) | Final | L | -22 |
| 27 | 2022-02-12 | Nebraska-Omaha (272) | 61 | 82 | South Dakota State (268) | Final | L | -21 |
| 28 | 2022-02-17 | Denver (253) | 69 | 72 | Nebraska-Omaha (272) | Final | W | 3 |
| 29 | 2022-02-24 | Nebraska-Omaha (343) | 76 | 88 | Western Illinois (232) | Final | L | -12 |
| 30 | 2022-02-26 | Nebraska-Omaha (343) | 74 | 95 | St. Thomas (313) | Final | L | -21 |
| 31 | 2022-03-05 | Nebraska-Omaha (344) | 79 | 87 | South Dakota State (50) | Final | L | -8 |