Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-01 | Minot State | 54 | 85 | North Dakota State (189) | Final | W | 31 |
| 2 | 2021-11-09 | Concordia College | 44 | 88 | North Dakota State (189) | Final | W | 44 |
| 3 | 2021-11-12 | North Dakota State (117) | 60 | 57 | Cal Poly (238) | Final | W | 3 |
| 4 | 2021-11-15 | North Dakota State (100) | 62 | 64 | UNLV (96) | Final | L | -2 |
| 5 | 2021-11-16 | North Dakota State (100) | 45 | 97 | Arizona (25) | Final | L | -52 |
| 6 | 2021-11-22 | Tarleton State (234) | 53 | 54 | North Dakota State (117) | Final | W | 1 |
| 7 | 2021-11-27 | Idaho (323) | 73 | 90 | North Dakota State (219) | Final | W | 17 |
| 8 | 2021-11-30 | North Dakota State (187) | 55 | 80 | Creighton (66) | Final | L | -25 |
| 9 | 2021-12-02 | Northland | 51 | 114 | North Dakota State (187) | Final | W | 63 |
| 10 | 2021-12-07 | North Dakota State (117) | 49 | 68 | Montana State (197) | Final | L | -19 |
| 11 | 2021-12-10 | Cal State-Northridge (260) | 54 | 68 | North Dakota State (209) | Final | W | 14 |
| 12 | 2021-12-13 | Indiana State (243) | 70 | 77 | North Dakota State (117) | Final | W | 7 |
| 13 | 2021-12-17 | North Dakota State (117) | 73 | 61 | Pacific (132) | Final | W | 12 |
| 14 | 2021-12-22 | North Dakota (251) | 76 | 86 | North Dakota State (117) | Final | W | 10 |
| 15 | 2021-12-30 | South Dakota State (268) | 90 | 86 | North Dakota State (117) | Final | L | -4 |
| 16 | 2022-01-01 | South Dakota (275) | 0 | 0 | North Dakota State (117) | Postponed | - | - |
| 17 | 2022-01-08 | North Dakota State (117) | 71 | 67 | Nebraska-Omaha (272) | Final | W | 4 |
| 18 | 2022-01-10 | North Dakota State (169) | 87 | 69 | Denver (315) | Final | W | 18 |
| 19 | 2022-01-13 | St. Thomas (137) | 0 | 0 | North Dakota State (117) | Postponed | - | - |
| 20 | 2022-01-15 | Western Illinois (362) | 90 | 79 | North Dakota State (117) | Final/OT | L | -11 |
| 21 | 2022-01-20 | North Dakota State (117) | 77 | 80 | UMKC (364) | Final | L | -3 |
| 22 | 2022-01-22 | North Dakota State (117) | 72 | 71 | Oral Roberts (327) | Final | W | 1 |
| 23 | 2022-01-25 | St. Thomas (270) | 56 | 77 | North Dakota State (187) | Final | W | 21 |
| 24 | 2022-01-27 | North Dakota State (117) | 74 | 62 | South Dakota (275) | Final/OT | W | 12 |
| 25 | 2022-01-29 | North Dakota State (117) | 76 | 80 | South Dakota State (268) | Final | L | -4 |
| 26 | 2022-02-03 | Nebraska-Omaha (272) | 64 | 71 | North Dakota State (117) | Final | W | 7 |
| 27 | 2022-02-05 | Denver (253) | 65 | 73 | North Dakota State (117) | Final | W | 8 |
| 28 | 2022-02-07 | South Dakota (275) | 74 | 76 | North Dakota State (117) | Final | W | 2 |
| 29 | 2022-02-10 | North Dakota State (117) | 84 | 81 | Western Illinois (362) | Final/2OT | W | 3 |
| 30 | 2022-02-12 | North Dakota State (117) | 75 | 64 | St. Thomas (137) | Final | W | 11 |
| 31 | 2022-02-17 | Oral Roberts (327) | 59 | 77 | North Dakota State (117) | Final | W | 18 |
| 32 | 2022-02-19 | UMKC (203) | 85 | 71 | North Dakota State (148) | Final | L | -14 |
| 33 | 2022-02-26 | North Dakota State (149) | 79 | 53 | North Dakota (344) | Final | W | 26 |
| 34 | 2022-03-05 | Denver (307) | 62 | 82 | North Dakota State (147) | Final | W | 20 |
| 35 | 2022-03-07 | Oral Roberts (151) | 72 | 92 | North Dakota State (144) | Final | W | 20 |
| 36 | 2022-03-08 | North Dakota State (144) | 69 | 75 | South Dakota State (52) | Final | L | -6 |