Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Hartford (161) | 59 | 77 | Wagner (160) | Final | L | -18 |
| 2 | 2021-11-12 | Hartford | 67 | 68 | Campbell (191) | Final | L | -1 |
| 3 | 2021-11-13 | Hartford (161) | 79 | 86 | Army (107) | Final | L | -7 |
| 4 | 2021-11-18 | Boston University (237) | 75 | 70 | Hartford (345) | Final | L | -5 |
| 5 | 2021-11-23 | Hartford (320) | 60 | 75 | Merrimack (243) | Final | L | -15 |
| 6 | 2021-11-29 | Hartford (334) | 59 | 69 | Appalachian State (190) | Final | L | -10 |
| 7 | 2021-12-01 | Hartford | 75 | 82 | Winthrop (133) | Final | L | -7 |
| 8 | 2021-12-05 | Hartford (334) | 68 | 55 | St. Francis (NY) (352) | Final | W | 13 |
| 9 | 2021-12-11 | Hartford | 78 | 95 | UNLV (105) | Final | L | -17 |
| 10 | 2021-12-14 | St. Francis (PA) (286) | 81 | 66 | Hartford (331) | Final | L | -15 |
| 11 | 2021-12-18 | Hartford | 65 | 75 | Central Connecticut State (258) | Final | L | -10 |
| 12 | 2021-12-22 | Hartford | 78 | 71 | Sacred Heart (270) | Final | W | 7 |
| 13 | 2021-12-28 | Hartford | 0 | 0 | Cornell (187) | Cancelled | - | - |
| 14 | 2022-01-02 | Stony Brook (213) | 0 | 0 | Hartford | Postponed | - | - |
| 15 | 2022-01-06 | Hartford | 0 | 0 | Maine (350) | Postponed | - | - |
| 16 | 2022-01-08 | Vermont (225) | 0 | 0 | Hartford | Postponed | - | - |
| 17 | 2022-01-15 | Hartford | 0 | 0 | UMass-Lowell (319) | Postponed | - | - |
| 18 | 2022-01-19 | New Hampshire (346) | 57 | 69 | Hartford | Final | W | 12 |
| 19 | 2022-01-22 | Hartford | 72 | 82 | Vermont (225) | Final | L | -10 |
| 20 | 2022-01-24 | Hartford | 64 | 74 | Binghamton (359) | Final | L | -10 |
| 21 | 2022-01-26 | Binghamton (278) | 60 | 72 | Hartford (324) | Final | W | 12 |
| 22 | 2022-01-29 | UMass-Lowell (319) | 0 | 0 | Hartford | Postponed | - | - |
| 23 | 2022-01-31 | Hartford (317) | 78 | 66 | Maine (354) | Final | W | 12 |
| 24 | 2022-02-02 | Hartford (317) | 64 | 70 | New Hampshire (262) | Final | L | -6 |
| 25 | 2022-02-05 | Albany (330) | 71 | 52 | Hartford | Final | L | -19 |
| 26 | 2022-02-07 | Hartford | 75 | 85 | UMass-Lowell (319) | Final | L | -10 |
| 27 | 2022-02-09 | Hartford | 64 | 68 | UMBC (198) | Final | L | -4 |
| 28 | 2022-02-12 | Hartford | 65 | 49 | NJIT (306) | Final | W | 16 |
| 29 | 2022-02-14 | Vermont (225) | 74 | 75 | Hartford | Final/OT | W | 1 |
| 30 | 2022-02-16 | Maine (352) | 65 | 75 | Hartford (322) | Final | W | 10 |
| 31 | 2022-02-19 | Hartford (322) | 82 | 88 | Stony Brook (193) | Final | L | -6 |
| 32 | 2022-02-20 | Stony Brook (216) | 70 | 74 | Hartford (300) | Final | W | 4 |
| 33 | 2022-02-23 | UMBC (237) | 92 | 85 | Hartford (300) | Final | L | -7 |
| 34 | 2022-02-26 | NJIT (292) | 62 | 83 | Hartford (300) | Final | W | 21 |
| 35 | 2022-03-01 | Hartford (294) | 67 | 55 | Albany (268) | Final | W | 12 |
| 36 | 2022-03-03 | UMass-Lowell (255) | 83 | 73 | Hartford (294) | Final | L | -10 |
| 37 | 2022-03-06 | Albany (281) | 49 | 61 | Hartford (290) | Final | W | 12 |
| 38 | 2022-03-09 | Hartford (290) | 60 | 80 | UMBC (220) | Final | L | -20 |