Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-01 | Blue Mountain | 66 | 72 | Arkansas State (248) | Final | W | 6 |
| 2 | 2021-11-09 | Harding | 55 | 81 | Arkansas State (248) | Final | W | 26 |
| 3 | 2021-11-12 | Arkansas State (147) | 53 | 92 | Illinois (9) | Final | L | -39 |
| 4 | 2021-11-15 | Central Baptist | 63 | 90 | Arkansas State (268) | Final | W | 27 |
| 5 | 2021-11-19 | Arkansas State (147) | 72 | 60 | Southeast Missouri State (226) | Final | W | 12 |
| 6 | 2021-11-26 | Morehead State (233) | 75 | 51 | Arkansas State (147) | Final | L | -24 |
| 7 | 2021-11-28 | UMKC (223) | 55 | 66 | Arkansas State (260) | Final | W | 11 |
| 8 | 2021-12-04 | Central Arkansas (143) | 82 | 95 | Arkansas State (147) | Final | W | 13 |
| 9 | 2021-12-08 | Arkansas State (218) | 84 | 73 | Arkansas-Pine Bluff (345) | Final | W | 11 |
| 10 | 2021-12-11 | Arkansas State (147) | 82 | 77 | Mississippi Valley State (365) | Final | W | 5 |
| 11 | 2021-12-14 | Arkansas State (147) | 62 | 75 | Texas Tech (20) | Final | L | -13 |
| 12 | 2021-12-19 | Air Force (347) | 46 | 68 | Arkansas State (147) | Final | W | 22 |
| 13 | 2021-12-21 | Lyon College | 66 | 88 | Arkansas State (147) | Final | W | 22 |
| 14 | 2021-12-21 | Champion Christian | 0 | 0 | Arkansas State | Cancelled | - | - |
| 15 | 2021-12-30 | Georgia State (299) | 0 | 0 | Arkansas State (147) | Cancelled | - | - |
| 16 | 2022-01-01 | Georgia Southern (216) | 56 | 74 | Arkansas State (147) | Final | W | 18 |
| 17 | 2022-01-06 | Arkansas State (147) | 77 | 83 | Louisiana (290) | Final/OT | L | -6 |
| 18 | 2022-01-08 | Arkansas State (147) | 90 | 83 | Louisiana-Monroe (358) | Final | W | 7 |
| 19 | 2022-01-13 | Little Rock (321) | 0 | 0 | Arkansas State (147) | Canceled | - | - |
| 20 | 2022-01-15 | Arkansas State (147) | 0 | 0 | Little Rock (321) | Canceled | - | - |
| 21 | 2022-01-20 | Texas-Arlington (162) | 70 | 75 | Arkansas State (147) | Final | W | 5 |
| 22 | 2022-01-22 | Texas State (199) | 60 | 67 | Arkansas State (147) | Final | W | 7 |
| 23 | 2022-01-27 | Arkansas State (147) | 54 | 61 | Appalachian State (159) | Final | L | -7 |
| 24 | 2022-01-29 | Arkansas State (147) | 73 | 66 | Coastal Carolina (188) | Final | W | 7 |
| 25 | 2022-02-03 | Louisiana-Monroe (358) | 60 | 59 | Arkansas State (147) | Final | L | -1 |
| 26 | 2022-02-05 | Louisiana (290) | 58 | 67 | Arkansas State (147) | Final | W | 9 |
| 27 | 2022-02-10 | Arkansas State (147) | 77 | 79 | Troy (127) | Final | L | -2 |
| 28 | 2022-02-12 | Arkansas State (147) | 51 | 70 | South Alabama (177) | Final | L | -19 |
| 29 | 2022-02-17 | Arkansas State (147) | 67 | 84 | Texas State (199) | Final | L | -17 |
| 30 | 2022-02-19 | Arkansas State (173) | 58 | 49 | Texas-Arlington (232) | Final | W | 9 |
| 31 | 2022-02-23 | Coastal Carolina (172) | 74 | 69 | Arkansas State (176) | Final | L | -5 |
| 32 | 2022-02-25 | Appalachian State (139) | 60 | 62 | Arkansas State (176) | Final | W | 2 |
| 33 | 2022-03-03 | Louisiana-Monroe (259) | 77 | 81 | Arkansas State (178) | Final | W | 4 |
| 34 | 2022-03-05 | Arkansas State (178) | 62 | 65 | Georgia State (169) | Final | L | -3 |