Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Carver Bible | 42 | 104 | Troy (252) | Final | W | 62 |
| 2 | 2021-11-13 | Troy (252) | 59 | 70 | Butler (115) | Final | L | -11 |
| 3 | 2021-11-16 | Jacksonville State (122) | 65 | 69 | Troy (192) | Final (3OT) | W | 4 |
| 4 | 2021-11-19 | Troy (127) | 72 | 74 | North Dakota (251) | Final | L | -2 |
| 5 | 2021-11-20 | Tennessee-Martin (205) | 67 | 80 | Troy (127) | Final | W | 13 |
| 6 | 2021-11-22 | Troy (127) | 83 | 78 | Florida Atlantic (128) | Final/OT | W | 5 |
| 7 | 2021-11-28 | Troy (194) | 45 | 84 | Florida (6) | Final | L | -39 |
| 8 | 2021-12-01 | Rust | 48 | 81 | Troy (127) | Final | W | 33 |
| 9 | 2021-12-05 | Southeastern Louisiana (329) | 72 | 68 | Troy (194) | Final | L | -4 |
| 10 | 2021-12-11 | Troy (127) | 75 | 72 | Tennessee Tech (310) | Final | W | 3 |
| 11 | 2021-12-14 | Alabama A&M (286) | 57 | 66 | Troy (127) | Final | W | 9 |
| 12 | 2021-12-18 | Arkansas Baptist | 64 | 84 | Troy (127) | Final | W | 20 |
| 13 | 2021-12-22 | Troy (127) | 69 | 65 | Mercer (174) | Final | W | 4 |
| 14 | 2021-12-30 | Troy (127) | 78 | 63 | Texas State (199) | Final | W | 15 |
| 15 | 2022-01-01 | Troy (127) | 57 | 62 | Texas-Arlington (162) | Final | L | -5 |
| 16 | 2022-01-06 | Coastal Carolina (188) | 59 | 69 | Troy (127) | Final | W | 10 |
| 17 | 2022-01-08 | Appalachian State (159) | 53 | 68 | Troy (127) | Final | W | 15 |
| 18 | 2022-01-13 | Georgia Southern (216) | 0 | 0 | Troy (127) | Canceled | - | - |
| 19 | 2022-01-15 | Georgia State (299) | 0 | 0 | Troy (127) | Canceled | - | - |
| 20 | 2022-01-20 | Troy (127) | 73 | 65 | Louisiana-Monroe (358) | Final | W | 8 |
| 21 | 2022-01-22 | Troy (127) | 59 | 69 | Louisiana (290) | Final | L | -10 |
| 22 | 2022-01-27 | Troy (127) | 63 | 82 | South Alabama (177) | Final | L | -19 |
| 23 | 2022-01-29 | South Alabama (177) | 68 | 77 | Troy (127) | Final | W | 9 |
| 24 | 2022-02-03 | Troy (127) | 67 | 63 | Georgia State (299) | Final | W | 4 |
| 25 | 2022-02-05 | Troy (127) | 61 | 52 | Georgia Southern (216) | Final | W | 9 |
| 26 | 2022-02-10 | Arkansas State (147) | 77 | 79 | Troy (127) | Final | W | 2 |
| 27 | 2022-02-12 | Little Rock (321) | 66 | 62 | Troy (127) | Final | L | -4 |
| 28 | 2022-02-17 | Troy (127) | 67 | 61 | Appalachian State (159) | Final | W | 6 |
| 29 | 2022-02-19 | Troy (155) | 63 | 73 | Coastal Carolina (178) | Final | L | -10 |
| 30 | 2022-02-23 | Texas-Arlington (231) | 53 | 59 | Troy (157) | Final | W | 6 |
| 31 | 2022-02-25 | Texas State (115) | 66 | 61 | Troy (157) | Final | L | -5 |
| 32 | 2022-03-05 | Little Rock (296) | 62 | 69 | Troy (153) | Final | W | 7 |
| 33 | 2022-03-06 | Louisiana (195) | 66 | 57 | Troy (167) | Final | L | -9 |
| 34 | 2022-03-20 | Abilene Christian (118) | 82 | 70 | Troy (166) | Final | L | -12 |