Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-06 | Kutztown | 76 | 78 | Rider (288) | Final | W | 2 |
| 2 | 2021-11-09 | Rider (288) | 61 | 73 | Duquesne (143) | Final | L | -12 |
| 3 | 2021-11-12 | Coppin State (360) | 69 | 81 | Rider (356) | Final | W | 12 |
| 4 | 2021-11-14 | Delaware State (361) | 53 | 63 | Rider (356) | Final | W | 10 |
| 5 | 2021-11-17 | Rider (356) | 74 | 81 | Bucknell (336) | Final | L | -7 |
| 6 | 2021-11-20 | Rider (356) | 65 | 87 | Buffalo (219) | Final | L | -22 |
| 7 | 2021-11-23 | Middle Tennessee (152) | 60 | 54 | Rider (308) | Final | L | -6 |
| 8 | 2021-11-24 | Rider (356) | 85 | 79 | Bucknell (336) | Final | W | 6 |
| 9 | 2021-11-28 | Rider (290) | 58 | 65 | South Carolina (52) | Final | L | -7 |
| 10 | 2021-11-30 | Rider (290) | 51 | 75 | Ole Miss (125) | Final | L | -24 |
| 11 | 2021-12-03 | Rider (356) | 54 | 80 | Iona (220) | Final | L | -26 |
| 12 | 2021-12-05 | Marist (261) | 79 | 67 | Rider (290) | Final | L | -12 |
| 13 | 2021-12-18 | Rider (356) | 0 | 0 | Rutgers (112) | Cancelled | - | - |
| 14 | 2021-12-20 | Gwynedd-Mercy | 57 | 82 | Rider (356) | Final | W | 25 |
| 15 | 2022-01-02 | Rider (356) | 0 | 0 | Quinnipiac (189) | Postponed | - | - |
| 16 | 2022-01-07 | Manhattan (307) | 0 | 0 | Rider (356) | Postponed | - | - |
| 17 | 2022-01-09 | Rider (291) | 79 | 75 | Marist (198) | Final | W | 4 |
| 18 | 2022-01-14 | Quinnipiac (220) | 77 | 70 | Rider (291) | Final (OT) | L | -7 |
| 19 | 2022-01-16 | Saint Peter's (223) | 58 | 51 | Rider (304) | Final | L | -7 |
| 20 | 2022-01-19 | Rider (356) | 67 | 73 | Quinnipiac (189) | Final | L | -6 |
| 21 | 2022-01-21 | Rider (304) | 69 | 70 | Canisius (277) | Final | L | -1 |
| 22 | 2022-01-23 | Rider (302) | 70 | 67 | Niagara (220) | Final | W | 3 |
| 23 | 2022-01-28 | Fairfield (213) | 76 | 65 | Rider (302) | Final | L | -11 |
| 24 | 2022-01-30 | Canisius (269) | 62 | 70 | Rider (292) | Final | W | 8 |
| 25 | 2022-02-04 | Rider (292) | 74 | 60 | Siena (218) | Final | W | 14 |
| 26 | 2022-02-08 | Manhattan (213) | 67 | 76 | Rider (285) | Final | W | 9 |
| 27 | 2022-02-11 | Rider (356) | 58 | 49 | Saint Peter's (200) | Final | W | 9 |
| 28 | 2022-02-13 | Siena (195) | 76 | 75 | Rider (270) | Final (OT) | L | -1 |
| 29 | 2022-02-18 | Rider (270) | 58 | 60 | Monmouth (120) | Final | L | -2 |
| 30 | 2022-02-20 | Rider (270) | 78 | 84 | Manhattan (207) | Final | L | -6 |
| 31 | 2022-02-25 | Niagara (209) | 68 | 70 | Rider (270) | Final | W | 2 |
| 32 | 2022-02-27 | Iona (49) | 67 | 61 | Rider (263) | Final | L | -6 |
| 33 | 2022-03-03 | Rider (263) | 59 | 65 | Fairfield (226) | Final | L | -6 |
| 34 | 2022-03-05 | Monmouth (128) | 65 | 74 | Rider (263) | Final | W | 9 |
| 35 | 2022-03-08 | Rider (262) | 79 | 67 | Manhattan (217) | Final | W | 12 |
| 36 | 2022-03-09 | Rider (262) | 71 | 70 | Iona (61) | Final | W | 1 |
| 37 | 2022-03-11 | Rider (262) | 68 | 72 | Monmouth (135) | Final | L | -4 |