Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Marist (209) | 73 | 77 | American (186) | Final (OT) | L | -4 |
| 2 | 2021-11-12 | Marist (178) | 82 | 67 | Columbia (193) | Final | W | 15 |
| 3 | 2021-11-17 | Marist (178) | 61 | 80 | Princeton (271) | Final | L | -19 |
| 4 | 2021-11-20 | Virginia Military (357) | 74 | 78 | Marist (178) | Final/OT | W | 4 |
| 5 | 2021-11-27 | Marist (197) | 61 | 65 | Army (188) | Final | L | -4 |
| 6 | 2021-12-01 | Iona (220) | 78 | 71 | Marist (178) | Final | L | -7 |
| 7 | 2021-12-05 | Marist (261) | 79 | 67 | Rider (290) | Final | W | 12 |
| 8 | 2021-12-08 | Marist (259) | 64 | 51 | Binghamton (285) | Final | W | 13 |
| 9 | 2021-12-12 | Navy (149) | 67 | 61 | Marist (178) | Final | L | -6 |
| 10 | 2021-12-18 | Marist (178) | 84 | 79 | Boston University (267) | Final/OT | W | 5 |
| 11 | 2021-12-22 | Bethune-Cookman (240) | 45 | 68 | Marist (178) | Final | W | 23 |
| 12 | 2021-12-31 | Marist (178) | 0 | 0 | Monmouth (176) | Postponed | - | - |
| 13 | 2022-01-02 | Marist (178) | 66 | 69 | Iona (220) | Final | L | -3 |
| 14 | 2022-01-07 | Marist (178) | 60 | 51 | Fairfield (204) | Final | W | 9 |
| 15 | 2022-01-09 | Rider (291) | 79 | 75 | Marist (198) | Final | L | -4 |
| 16 | 2022-01-11 | Marist (178) | 0 | 0 | Monmouth (176) | Postponed | - | - |
| 17 | 2022-01-14 | Siena (263) | 67 | 60 | Marist (198) | Final | L | -7 |
| 18 | 2022-01-16 | Monmouth (109) | 48 | 84 | Marist (192) | Final | W | 36 |
| 19 | 2022-01-23 | Fairfield (213) | 69 | 66 | Marist (205) | Final | L | -3 |
| 20 | 2022-01-26 | Saint Peter's (209) | 69 | 62 | Marist (205) | Final | L | -7 |
| 21 | 2022-01-28 | Marist (205) | 87 | 94 | Quinnipiac (217) | Final | L | -7 |
| 22 | 2022-01-30 | Marist (234) | 66 | 72 | Manhattan (192) | Final | L | -6 |
| 23 | 2022-02-06 | Marist (178) | 50 | 66 | Saint Peter's (200) | Final | L | -16 |
| 24 | 2022-02-12 | Canisius (328) | 70 | 71 | Marist (178) | Final | W | 1 |
| 25 | 2022-02-14 | Niagara (342) | 70 | 77 | Marist (178) | Final | W | 7 |
| 26 | 2022-02-18 | Marist (223) | 62 | 53 | Siena (195) | Final | W | 9 |
| 27 | 2022-02-20 | Quinnipiac (234) | 66 | 67 | Marist (200) | Final | W | 1 |
| 28 | 2022-02-25 | Manhattan (207) | 56 | 74 | Marist (200) | Final | W | 18 |
| 29 | 2022-03-03 | Marist (197) | 67 | 78 | Canisius (269) | Final | L | -11 |
| 30 | 2022-03-05 | Marist (197) | 52 | 83 | Niagara (225) | Final | L | -31 |
| 31 | 2022-03-08 | Quinnipiac (249) | 77 | 52 | Marist (214) | Final | L | -25 |