Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Navy (68) | 66 | 58 | Virginia (18) | Final | W | 8 |
| 2 | 2021-11-12 | Virginia Tech (56) | 77 | 57 | Navy (149) | Final | L | -20 |
| 3 | 2021-11-15 | Navy (144) | 60 | 77 | Louisville (140) | Final | L | -17 |
| 4 | 2021-11-20 | Radford (255) | 33 | 47 | Navy (149) | Final | W | 14 |
| 5 | 2021-11-21 | Navy (135) | 77 | 66 | Furman (150) | Final | W | 11 |
| 6 | 2021-11-24 | Washington College | 40 | 89 | Navy (135) | Final | W | 49 |
| 7 | 2021-11-27 | Navy (135) | 67 | 40 | Mount St Mary's (268) | Final | W | 27 |
| 8 | 2021-12-01 | William & Mary (141) | 56 | 75 | Navy (149) | Final | W | 19 |
| 9 | 2021-12-07 | Navy (149) | 65 | 71 | George Mason (86) | Final | L | -6 |
| 10 | 2021-12-12 | Navy (149) | 67 | 61 | Marist (178) | Final | W | 6 |
| 11 | 2021-12-22 | Towson (152) | 69 | 52 | Navy (149) | Final | L | -17 |
| 12 | 2022-01-01 | Navy (149) | 70 | 56 | Holy Cross (334) | Final | W | 14 |
| 13 | 2022-01-04 | Boston University (267) | 71 | 83 | Navy (149) | Final | W | 12 |
| 14 | 2022-01-07 | Bucknell (336) | 55 | 73 | Navy (149) | Final | W | 18 |
| 15 | 2022-01-10 | Navy (112) | 69 | 55 | Lafayette (318) | Final | W | 14 |
| 16 | 2022-01-13 | Colgate (239) | 69 | 50 | Navy (149) | Final | L | -19 |
| 17 | 2022-01-16 | Navy (126) | 72 | 65 | Boston University (206) | Final | W | 7 |
| 18 | 2022-01-19 | Lehigh (276) | 69 | 61 | Navy (149) | Final | L | -8 |
| 19 | 2022-01-22 | Army (339) | 74 | 73 | Navy (149) | Final/OT | L | -1 |
| 20 | 2022-01-26 | Navy (158) | 81 | 63 | Bucknell (336) | Final | W | 18 |
| 21 | 2022-01-29 | American (249) | 45 | 47 | Navy (149) | Final | W | 2 |
| 22 | 2022-02-02 | Navy (154) | 62 | 63 | Lehigh (306) | Final | L | -1 |
| 23 | 2022-02-05 | Navy (149) | 56 | 55 | Loyola-Maryland (325) | Final | W | 1 |
| 24 | 2022-02-07 | Lafayette (323) | 44 | 68 | Navy (149) | Final | W | 24 |
| 25 | 2022-02-12 | Navy (149) | 52 | 49 | Army (339) | Final | W | 3 |
| 26 | 2022-02-16 | Navy (159) | 55 | 46 | American (339) | Final | W | 9 |
| 27 | 2022-02-19 | Holy Cross (327) | 55 | 50 | Navy (159) | Final | L | -5 |
| 28 | 2022-02-23 | Loyola-Maryland (267) | 50 | 52 | Navy (173) | Final | W | 2 |
| 29 | 2022-02-26 | Navy (173) | 69 | 74 | Colgate (182) | Final | L | -5 |
| 30 | 2022-03-03 | American (330) | 64 | 71 | Navy (179) | Final | W | 7 |
| 31 | 2022-03-06 | Boston University (211) | 80 | 85 | Navy (173) | Final | W | 5 |
| 32 | 2022-03-09 | Navy (173) | 58 | 74 | Colgate (168) | Final | L | -16 |