Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-10 | Northern Colorado (271) | 67 | 65 | Pacific (117) | Final | W | 2 |
| 2 | 2021-11-12 | Northern Colorado (271) | 81 | 78 | Hawaii (194) | Final | W | 3 |
| 3 | 2021-11-13 | Hawaii-Hilo | 87 | 79 | Northern Colorado (271) | Final (OT) | L | -8 |
| 4 | 2021-11-15 | Colorado College | 53 | 93 | Northern Colorado (271) | Final | W | 40 |
| 5 | 2021-11-17 | Northern Colorado (196) | 49 | 62 | Texas (41) | Final | L | -13 |
| 6 | 2021-11-21 | Northern Colorado (281) | 70 | 74 | California Baptist (86) | Final | L | -4 |
| 7 | 2021-11-23 | Northern Colorado (281) | 74 | 75 | San Jose State (242) | Final | L | -1 |
| 8 | 2021-11-27 | Northern Colorado (281) | 79 | 88 | Colorado State (40) | Final | L | -9 |
| 9 | 2021-12-02 | Montana State (191) | 75 | 77 | Northern Colorado (283) | Final (OT) | W | 2 |
| 10 | 2021-12-04 | Montana (230) | 75 | 78 | Northern Colorado (196) | Final | W | 3 |
| 11 | 2021-12-07 | South Dakota (275) | 69 | 74 | Northern Colorado (196) | Final | W | 5 |
| 12 | 2021-12-15 | Northern Colorado (196) | 76 | 101 | Arizona (2) | Final | L | -25 |
| 13 | 2021-12-18 | Northern Colorado (196) | 56 | 82 | Washington State (179) | Final | L | -26 |
| 14 | 2021-12-21 | Northern New Mexico | 54 | 90 | Northern Colorado (196) | Final | W | 36 |
| 15 | 2022-01-01 | Northern Colorado (196) | 91 | 81 | Southern Utah (282) | Final | W | 10 |
| 16 | 2022-01-08 | Sacramento State (313) | 85 | 71 | Northern Colorado (196) | Final | L | -14 |
| 17 | 2022-01-15 | Northern Arizona (324) | 0 | 0 | Northern Colorado (196) | Postponed | - | - |
| 18 | 2022-01-20 | Northern Colorado (196) | 87 | 70 | Idaho (209) | Final | W | 17 |
| 19 | 2022-01-22 | Northern Colorado (196) | 87 | 83 | Eastern Washington (242) | Final | W | 4 |
| 20 | 2022-01-27 | Weber State (235) | 85 | 76 | Northern Colorado (196) | Final | L | -9 |
| 21 | 2022-01-29 | Idaho State (289) | 0 | 0 | Northern Colorado (196) | Postponed | - | - |
| 22 | 2022-01-31 | Northern Colorado (206) | 76 | 79 | Portland State (327) | Final | L | -3 |
| 23 | 2022-02-03 | Portland State (192) | 106 | 99 | Northern Colorado (196) | Final | L | -7 |
| 24 | 2022-02-05 | Northern Colorado (196) | 74 | 71 | Northern Arizona (324) | Final | W | 3 |
| 25 | 2022-02-07 | Northern Arizona (324) | 60 | 82 | Northern Colorado (196) | Final | W | 22 |
| 26 | 2022-02-10 | Northern Colorado (196) | 79 | 61 | Sacramento State (313) | Final | W | 18 |
| 27 | 2022-02-14 | Southern Utah (282) | 95 | 100 | Northern Colorado (196) | Final | W | 5 |
| 28 | 2022-02-17 | Northern Colorado (196) | 58 | 61 | Idaho State (289) | Final | L | -3 |
| 29 | 2022-02-19 | Northern Colorado (225) | 83 | 79 | Weber State (142) | Final | W | 4 |
| 30 | 2022-02-21 | Idaho State (339) | 70 | 77 | Northern Colorado (217) | Final | W | 7 |
| 31 | 2022-02-24 | Eastern Washington (228) | 85 | 76 | Northern Colorado (217) | Final | L | -9 |
| 32 | 2022-02-26 | Idaho (314) | 94 | 98 | Northern Colorado (217) | Final | W | 4 |
| 33 | 2022-03-03 | Northern Colorado (217) | 75 | 66 | Montana (203) | Final | W | 9 |
| 34 | 2022-03-05 | Northern Colorado (217) | 85 | 87 | Montana State (133) | Final | L | -2 |
| 35 | 2022-03-10 | Eastern Washington (222) | 67 | 68 | Northern Colorado (215) | Final | W | 1 |
| 36 | 2022-03-11 | Portland State (276) | 79 | 86 | Northern Colorado (215) | Final | W | 7 |
| 37 | 2022-03-12 | Northern Colorado (215) | 66 | 87 | Montana State (120) | Final | L | -21 |
| 38 | 2022-03-20 | Florida Atlantic (162) | 71 | 74 | Northern Colorado (209) | Final | W | 3 |
| 39 | 2022-03-21 | Northern Colorado (209) | 87 | 84 | UNC-Asheville (228) | Final | W | 3 |
| 40 | 2022-03-22 | UNC-Wilmington (131) | 80 | 64 | Northern Colorado (209) | Final | L | -16 |