Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | UC-Irvine (106) | 51 | 62 | New Mexico State (195) | Final | W | 11 |
| 2 | 2021-11-13 | UTEP (184) | 71 | 77 | New Mexico State (195) | Final | W | 6 |
| 3 | 2021-11-18 | Davidson (124) | 64 | 75 | New Mexico State (41) | Final | W | 11 |
| 4 | 2021-11-19 | New Mexico State (207) | 58 | 85 | Utah State (25) | Final | L | -27 |
| 5 | 2021-11-21 | New Mexico State (42) | 80 | 66 | Indiana State (171) | Final | W | 14 |
| 6 | 2021-11-24 | New Mexico Highlands | 67 | 94 | New Mexico State (207) | Final | W | 27 |
| 7 | 2021-11-30 | New Mexico (177) | 101 | 94 | New Mexico State (62) | Final | L | -7 |
| 8 | 2021-12-03 | New Mexico State (207) | 72 | 69 | UTEP (274) | Final | W | 3 |
| 9 | 2021-12-06 | New Mexico State (87) | 78 | 76 | New Mexico (133) | Final (OT) | W | 2 |
| 10 | 2021-12-11 | New Mexico State (207) | 63 | 58 | Loyola Marymount (184) | Final | W | 5 |
| 11 | 2021-12-15 | New Mexico State (207) | 64 | 61 | Washington State (179) | Final | W | 3 |
| 12 | 2021-12-18 | Northern New Mexico | 60 | 93 | New Mexico State (207) | Final | W | 33 |
| 13 | 2021-12-20 | Texas Permian Basin | 59 | 84 | New Mexico State (207) | Final | W | 25 |
| 14 | 2021-12-21 | Cal State-Fullerton | 0 | 0 | New Mexico State | Cancelled | - | - |
| 15 | 2021-12-30 | New Mexico State (207) | 0 | 0 | Seattle (118) | Postponed | - | - |
| 16 | 2022-01-01 | Chicago State (351) | 61 | 78 | New Mexico State (207) | Final | W | 17 |
| 17 | 2022-01-06 | New Mexico State (207) | 2 | 0 | Lamar (279) | Forfeit | W | 2 |
| 18 | 2022-01-08 | New Mexico State (207) | 85 | 73 | UTRGV (161) | Final | W | 12 |
| 19 | 2022-01-13 | Tarleton State (234) | 57 | 73 | New Mexico State (207) | Final | W | 16 |
| 20 | 2022-01-15 | Abilene Christian (245) | 63 | 77 | New Mexico State (207) | Final | W | 14 |
| 21 | 2022-01-20 | New Mexico State (207) | 46 | 71 | Sam Houston State (120) | Final | L | -25 |
| 22 | 2022-01-22 | New Mexico State (207) | 72 | 58 | Stephen F. Austin (88) | Final | W | 14 |
| 23 | 2022-01-29 | Grand Canyon (74) | 61 | 71 | New Mexico State (207) | Final | W | 10 |
| 24 | 2022-02-03 | California Baptist (97) | 57 | 68 | New Mexico State (207) | Final | W | 11 |
| 25 | 2022-02-05 | Seattle (118) | 64 | 79 | New Mexico State (207) | Final | W | 15 |
| 26 | 2022-02-10 | New Mexico State (207) | 77 | 69 | Utah Tech (186) | Final | W | 8 |
| 27 | 2022-02-10 | New Mexico State (56) | 77 | 69 | Dixie State (271) | Final | W | 8 |
| 28 | 2022-02-12 | New Mexico State (207) | 68 | 72 | Utah Valley (91) | Final | L | -4 |
| 29 | 2022-02-16 | Dixie State (254) | 64 | 75 | New Mexico State (72) | Final | W | 11 |
| 30 | 2022-02-19 | New Mexico State (72) | 82 | 66 | Grand Canyon (104) | Final | W | 16 |
| 31 | 2022-02-21 | New Mexico State (62) | 68 | 55 | Seattle (106) | Final | W | 13 |
| 32 | 2022-02-26 | New Mexico State (62) | 59 | 61 | Chicago State (340) | Final | L | -2 |
| 33 | 2022-03-02 | Stephen F. Austin (115) | 73 | 71 | New Mexico State (72) | Final | L | -2 |
| 34 | 2022-03-05 | Utah Valley (114) | 46 | 62 | New Mexico State (72) | Final | W | 16 |
| 35 | 2022-03-11 | Grand Canyon (94) | 70 | 75 | New Mexico State (76) | Final | W | 5 |
| 36 | 2022-03-12 | Abilene Christian (129) | 52 | 66 | New Mexico State (76) | Final | W | 14 |
| 37 | 2022-03-17 | New Mexico State (68) | 70 | 63 | Connecticut (17) | Final | W | 7 |
| 38 | 2022-03-19 | New Mexico State (68) | 48 | 53 | Arkansas (18) | Final | L | -5 |