NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Bethel (TN) | 46 | 85 | Tennessee Tech (145) | Final | W | 39 |
| 2 | 2021-11-13 | Chattanooga (198) | 58 | 85 | Tennessee Tech (145) | Final | W | 27 |
| 3 | 2021-11-18 | Tennessee Tech (222) | 55 | 75 | Vanderbilt (7) | Final | L | -20 |
| 4 | 2021-11-22 | Middle Tennessee (37) | 65 | 47 | Tennessee Tech (107) | Final | L | -18 |
| 5 | 2021-11-26 | Tennessee Tech (222) | 69 | 81 | Florida Gulf Coast (172) | Final | L | -12 |
| 6 | 2021-11-27 | Tennessee Tech (196) | 54 | 66 | New Mexico State (165) | Final | L | -12 |
| 7 | 2021-12-01 | Tennessee Tech (247) | 48 | 76 | Tennessee (3) | Final | L | -28 |
| 8 | 2021-12-05 | Tennessee Tech (247) | 76 | 72 | Western Kentucky (181) | Final | W | 4 |
| 9 | 2021-12-09 | Tennessee Tech (210) | 67 | 50 | Western Carolina (316) | Final | W | 17 |
| 10 | 2021-12-16 | Tennessee Wesleyan | 34 | 84 | Tennessee Tech (197) | Final | W | 50 |
| 11 | 2021-12-21 | Samford (280) | 0 | 0 | Tennessee Tech (190) | Cancelled | - | - |
| 12 | 2021-12-30 | Tennessee Tech (185) | 93 | 96 | Tennessee State (225) | Final/OT | L | -3 |
| 13 | 2022-01-01 | Tennessee Tech (185) | 65 | 62 | Murray State (153) | Final | W | 3 |
| 14 | 2022-01-06 | Morehead State (351) | 48 | 78 | Tennessee Tech (180) | Final | W | 30 |
| 15 | 2022-01-08 | Murray State (52) | 70 | 45 | Tennessee Tech (222) | Final | L | -25 |
| 16 | 2022-01-13 | Tennessee Tech (222) | 75 | 58 | Southeast Missouri State (243) | Final | W | 17 |
| 17 | 2022-01-15 | Tennessee Tech (190) | 0 | 0 | Tennessee-Martin (214) | Postponed | - | - |
| 18 | 2022-01-20 | SIU-Edwardsville (250) | 60 | 75 | Tennessee Tech (182) | Final | W | 15 |
| 19 | 2022-01-22 | Tennessee Tech (182) | 57 | 55 | Belmont (80) | Final | W | 2 |
| 20 | 2022-01-24 | Eastern Illinois (253) | 60 | 65 | Tennessee Tech (182) | Final | W | 5 |
| 21 | 2022-01-29 | Austin Peay (188) | 56 | 59 | Tennessee Tech (152) | Final | W | 3 |
| 22 | 2022-01-31 | Tennessee Tech (222) | 67 | 56 | Tennessee-Martin (249) | Final | W | 11 |
| 23 | 2022-02-03 | Tennessee Tech (140) | 87 | 69 | Morehead State (353) | Final | W | 18 |
| 24 | 2022-02-05 | Belmont (102) | 58 | 49 | Tennessee Tech (222) | Final | L | -9 |
| 25 | 2022-02-10 | Tennessee Tech (222) | 65 | 56 | Eastern Illinois (329) | Final | W | 9 |
| 26 | 2022-02-12 | Tennessee Tech (148) | 68 | 64 | SIU-Edwardsville (256) | Final | W | 4 |
| 27 | 2022-02-17 | Southeast Missouri State (332) | 55 | 65 | Tennessee Tech (137) | Final | W | 10 |
| 28 | 2022-02-19 | Tennessee Tech (137) | 61 | 71 | Austin Peay (176) | Final | L | -10 |
| 29 | 2022-02-24 | Tennessee State (265) | 49 | 75 | Tennessee Tech (153) | Final | W | 26 |
| 30 | 2022-02-26 | Tennessee-Martin (211) | 51 | 61 | Tennessee Tech (153) | Final | W | 10 |
| 31 | 2022-03-04 | Murray State (131) | 62 | 68 | Tennessee Tech (142) | Final | W | 6 |
| 32 | 2022-03-05 | Tennessee Tech (142) | 29 | 51 | Belmont (73) | Final | L | -22 |
| 33 | 2022-03-17 | Tennessee Tech (142) | 73 | 62 | SMU (100) | Final | W | 11 |
| 34 | 2022-03-20 | Tennessee Tech (142) | 55 | 63 | Houston (79) | Final | L | -8 |