NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Emory & Henry | 48 | 72 | Western Carolina (317) | Final | W | 24 |
| 2 | 2021-11-12 | UNC-Asheville (308) | 74 | 72 | Western Carolina (353) | Final/OT | L | -2 |
| 3 | 2021-11-16 | Presbyterian (340) | 51 | 52 | Western Carolina (276) | Final | W | 1 |
| 4 | 2021-11-20 | Charleston Southern (341) | 48 | 74 | Western Carolina (276) | Final | W | 26 |
| 5 | 2021-11-23 | Western Carolina (353) | 45 | 46 | Cincinnati (122) | Final | L | -1 |
| 6 | 2021-11-26 | Western Carolina (353) | 43 | 77 | Alabama (21) | Final | L | -34 |
| 7 | 2021-11-29 | Mars Hill | 51 | 70 | Western Carolina (200) | Final | W | 19 |
| 8 | 2021-12-01 | South Carolina Upstate (207) | 58 | 51 | Western Carolina (277) | Final/OT | L | -7 |
| 9 | 2021-12-04 | Western Carolina (353) | 55 | 71 | Winthrop (276) | Final | L | -16 |
| 10 | 2021-12-06 | Western Carolina (277) | 40 | 53 | Campbell (239) | Final | L | -13 |
| 11 | 2021-12-09 | Tennessee Tech (210) | 67 | 50 | Western Carolina (316) | Final | L | -17 |
| 12 | 2021-12-12 | Western Carolina (316) | 61 | 52 | South Carolina State (354) | Final | W | 9 |
| 13 | 2021-12-20 | Davidson (104) | 68 | 46 | Western Carolina (321) | Final | L | -22 |
| 14 | 2021-12-31 | Southern Wesleyan | 0 | 0 | Western Carolina (353) | Postponed | - | - |
| 15 | 2022-01-02 | Montreat | 23 | 79 | Western Carolina (353) | Final | W | 56 |
| 16 | 2022-01-06 | Western Carolina (315) | 48 | 72 | Wofford (266) | Final | L | -24 |
| 17 | 2022-01-08 | Western Carolina (353) | 59 | 71 | Furman (198) | Final | L | -12 |
| 18 | 2022-01-13 | Samford (256) | 62 | 47 | Western Carolina (353) | Final | L | -15 |
| 19 | 2022-01-15 | Mercer (115) | 69 | 58 | Western Carolina (330) | Final | L | -11 |
| 20 | 2022-01-17 | Southern Wesleyan | 0 | 0 | Western Carolina (330) | Postponed | - | - |
| 21 | 2022-01-20 | Western Carolina (331) | 48 | 55 | Chattanooga (304) | Final | L | -7 |
| 22 | 2022-01-22 | Western Carolina (331) | 45 | 68 | East Tennessee State (338) | Final | L | -23 |
| 23 | 2022-01-29 | UNC-Greensboro (311) | 64 | 29 | Western Carolina (334) | Final | L | -35 |
| 24 | 2022-02-03 | Furman (255) | 63 | 58 | Western Carolina (335) | Final | L | -5 |
| 25 | 2022-02-05 | Wofford (220) | 71 | 49 | Western Carolina (353) | Final | L | -22 |
| 26 | 2022-02-10 | Western Carolina (353) | 40 | 46 | Mercer (245) | Final | L | -6 |
| 27 | 2022-02-12 | Western Carolina (339) | 51 | 64 | Samford (266) | Final | L | -13 |
| 28 | 2022-02-17 | East Tennessee State (333) | 58 | 51 | Western Carolina (339) | Final | L | -7 |
| 29 | 2022-02-19 | Chattanooga (311) | 63 | 47 | Western Carolina (339) | Final | L | -16 |
| 30 | 2022-02-22 | Emory & Henry | 39 | 42 | Western Carolina (341) | Final | W | 3 |
| 31 | 2022-02-26 | Western Carolina (341) | 39 | 67 | UNC-Greensboro (314) | Final | L | -28 |
| 32 | 2022-03-03 | Western Carolina (342) | 46 | 85 | Mercer (106) | Final | L | -39 |