NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Morehead State (275) | 31 | 93 | Michigan State (40) | Final | L | -62 |
| 2 | 2021-11-19 | Morehead State (288) | 58 | 65 | Marshall (95) | Final | L | -7 |
| 3 | 2021-11-21 | Midway | 53 | 72 | Morehead State (288) | Final | W | 19 |
| 4 | 2021-11-24 | Morehead State (309) | 45 | 69 | Robert Morris (279) | Final | L | -24 |
| 5 | 2021-11-27 | Morehead State (309) | 61 | 68 | Bellarmine (329) | Final | L | -7 |
| 6 | 2021-11-30 | Morehead State (346) | 28 | 73 | Baylor (32) | Final | L | -45 |
| 7 | 2021-12-11 | Morehead State (346) | 49 | 79 | Evansville (216) | Final | L | -30 |
| 8 | 2021-12-15 | Eastern Kentucky (295) | 66 | 43 | Morehead State (349) | Final | L | -23 |
| 9 | 2021-12-18 | South Carolina Upstate (315) | 66 | 52 | Morehead State (183) | Final | L | -14 |
| 10 | 2021-12-19 | Valparaiso (360) | 65 | 57 | Morehead State (183) | Final | L | -8 |
| 11 | 2021-12-29 | Eastern Illinois (231) | 91 | 64 | Morehead State (349) | Final | L | -27 |
| 12 | 2022-01-01 | Tennessee State (225) | 58 | 34 | Morehead State (349) | Final | L | -24 |
| 13 | 2022-01-06 | Morehead State (351) | 48 | 78 | Tennessee Tech (180) | Final | L | -30 |
| 14 | 2022-01-08 | Morehead State (183) | 49 | 66 | Austin Peay (177) | Final | L | -17 |
| 15 | 2022-01-15 | Morehead State (351) | 0 | 0 | Tennessee State (187) | Postponed | - | - |
| 16 | 2022-01-20 | Belmont (80) | 103 | 50 | Morehead State (353) | Final | L | -53 |
| 17 | 2022-01-22 | SIU-Edwardsville (250) | 77 | 52 | Morehead State (353) | Final | L | -25 |
| 18 | 2022-01-24 | Tennessee-Martin (216) | 64 | 50 | Morehead State (353) | Final | L | -14 |
| 19 | 2022-01-27 | Morehead State (183) | 53 | 60 | Southeast Missouri State (243) | Final | L | -7 |
| 20 | 2022-01-29 | Morehead State (353) | 44 | 79 | Murray State (141) | Final | L | -35 |
| 21 | 2022-01-31 | Morehead State (183) | 60 | 77 | Tennessee State (322) | Final | L | -17 |
| 22 | 2022-02-03 | Tennessee Tech (140) | 87 | 69 | Morehead State (353) | Final | L | -18 |
| 23 | 2022-02-05 | Austin Peay (177) | 71 | 61 | Morehead State (183) | Final | L | -10 |
| 24 | 2022-02-10 | Morehead State (183) | 51 | 76 | Belmont (102) | Final | L | -25 |
| 25 | 2022-02-12 | Murray State (142) | 72 | 58 | Morehead State (354) | Final | L | -14 |
| 26 | 2022-02-16 | Morehead State (183) | 36 | 54 | Tennessee-Martin (249) | Final | L | -18 |
| 27 | 2022-02-19 | Southeast Missouri State (332) | 70 | 62 | Morehead State (353) | Final | L | -8 |
| 28 | 2022-02-24 | Morehead State (354) | 56 | 68 | Eastern Illinois (206) | Final | L | -12 |
| 29 | 2022-02-26 | Morehead State (354) | 77 | 94 | SIU-Edwardsville (262) | Final | L | -17 |