NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Fisk | 48 | 94 | Tennessee State (342) | Final | W | 46 |
| 2 | 2021-11-12 | Tennessee State (322) | 70 | 67 | Georgia State (250) | Final | W | 3 |
| 3 | 2021-11-14 | Tennessee State (342) | 60 | 83 | Kansas (153) | Final | L | -23 |
| 4 | 2021-11-17 | Chattanooga (312) | 63 | 57 | Tennessee State (194) | Final | L | -6 |
| 5 | 2021-11-23 | Tennessee State (322) | 83 | 71 | North Alabama (230) | Final | W | 12 |
| 6 | 2021-11-28 | Tennessee State (241) | 65 | 77 | Western Kentucky (263) | Final | L | -12 |
| 7 | 2021-12-02 | Tennessee State (265) | 56 | 67 | Nebraska-Omaha (258) | Final | L | -11 |
| 8 | 2021-12-05 | Mercer (99) | 71 | 70 | Tennessee State (265) | Final/OT | L | -1 |
| 9 | 2021-12-12 | UMKC (60) | 74 | 70 | Tennessee State (282) | Final | L | -4 |
| 10 | 2021-12-15 | Tennessee State (264) | 50 | 49 | Lipscomb (299) | Final | W | 1 |
| 11 | 2021-12-18 | Virginia Commonwealth (235) | 0 | 0 | Tennessee State (322) | Cancelled | - | - |
| 12 | 2021-12-19 | Tennessee State (322) | 60 | 56 | Stetson (170) | Final | W | 4 |
| 13 | 2021-12-30 | Tennessee Tech (185) | 93 | 96 | Tennessee State (225) | Final/OT | W | 3 |
| 14 | 2022-01-01 | Tennessee State (225) | 58 | 34 | Morehead State (349) | Final | W | 24 |
| 15 | 2022-01-06 | Tennessee-Martin (210) | 65 | 66 | Tennessee State (200) | Final | W | 1 |
| 16 | 2022-01-08 | Southeast Missouri State (243) | 64 | 83 | Tennessee State (322) | Final | W | 19 |
| 17 | 2022-01-13 | Tennessee State (322) | 62 | 76 | Murray State (52) | Final | L | -14 |
| 18 | 2022-01-15 | Morehead State (351) | 0 | 0 | Tennessee State (187) | Postponed | - | - |
| 19 | 2022-01-20 | Tennessee State (196) | 68 | 53 | Southeast Missouri State (325) | Final | W | 15 |
| 20 | 2022-01-22 | Austin Peay (190) | 72 | 69 | Tennessee State (196) | Final | L | -3 |
| 21 | 2022-01-27 | Tennessee State (322) | 72 | 79 | SIU-Edwardsville (242) | Final | L | -7 |
| 22 | 2022-01-29 | Tennessee State (204) | 70 | 78 | Eastern Illinois (224) | Final/OT | L | -8 |
| 23 | 2022-01-31 | Morehead State (183) | 60 | 77 | Tennessee State (322) | Final | W | 17 |
| 24 | 2022-02-03 | Belmont (92) | 85 | 46 | Tennessee State (234) | Final | L | -39 |
| 25 | 2022-02-05 | Tennessee State (322) | 46 | 55 | Tennessee-Martin (249) | Final | L | -9 |
| 26 | 2022-02-10 | Murray State (52) | 79 | 53 | Tennessee State (322) | Final | L | -26 |
| 27 | 2022-02-12 | Tennessee State (249) | 37 | 57 | Austin Peay (176) | Final | L | -20 |
| 28 | 2022-02-17 | SIU-Edwardsville (266) | 86 | 76 | Tennessee State (259) | Final | L | -10 |
| 29 | 2022-02-19 | Eastern Illinois (202) | 72 | 61 | Tennessee State (259) | Final | L | -11 |
| 30 | 2022-02-24 | Tennessee State (265) | 49 | 75 | Tennessee Tech (153) | Final | L | -26 |
| 31 | 2022-02-26 | Tennessee State (265) | 44 | 82 | Belmont (79) | Final | L | -38 |
| 32 | 2022-03-02 | Tennessee State (274) | 72 | 61 | Eastern Illinois (197) | Final | W | 11 |
| 33 | 2022-03-03 | Tennessee State (274) | 53 | 67 | Austin Peay (194) | Final | L | -14 |