NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-10 | Southern Illinois (195) | 49 | 59 | Tennessee (11) | Final | W | 10 |
| 2 | 2021-11-12 | Tennessee (33) | 49 | 41 | Central Florida (150) | Final | W | 8 |
| 3 | 2021-11-15 | South Florida (15) | 49 | 52 | Tennessee (11) | Final | W | 3 |
| 4 | 2021-11-21 | Texas (12) | 70 | 74 | Tennessee (21) | Final/OT | W | 4 |
| 5 | 2021-11-26 | Tennessee (33) | 68 | 58 | Kansas (49) | Final | W | 10 |
| 6 | 2021-11-27 | Oklahoma State (40) | 55 | 80 | Tennessee (8) | Final | W | 25 |
| 7 | 2021-12-01 | Tennessee Tech (247) | 48 | 76 | Tennessee (3) | Final | W | 28 |
| 8 | 2021-12-05 | Tennessee (3) | 64 | 58 | Virginia Tech (20) | Final | W | 6 |
| 9 | 2021-12-12 | Georgia State (297) | 60 | 84 | Tennessee (3) | Final | W | 24 |
| 10 | 2021-12-18 | Stanford (56) | 74 | 63 | Tennessee (33) | Final | L | -11 |
| 11 | 2021-12-20 | East Tennessee State (326) | 58 | 112 | Tennessee (3) | Final | W | 54 |
| 12 | 2021-12-27 | Chattanooga (321) | 41 | 91 | Tennessee (7) | Final | W | 50 |
| 13 | 2021-12-30 | Alabama (40) | 44 | 62 | Tennessee (6) | Final | W | 18 |
| 14 | 2022-01-02 | Tennessee (33) | 70 | 63 | Arkansas (114) | Final | W | 7 |
| 15 | 2022-01-06 | Texas A&M (26) | 45 | 73 | Tennessee (3) | Final | W | 28 |
| 16 | 2022-01-09 | Tennessee (33) | 70 | 58 | Ole Miss (22) | Final | W | 12 |
| 17 | 2022-01-13 | Tennessee (33) | 65 | 51 | Vanderbilt (7) | Final | W | 14 |
| 18 | 2022-01-16 | Kentucky (16) | 58 | 84 | Tennessee (33) | Final | W | 26 |
| 19 | 2022-01-17 | Kentucky | Tennessee | TBD | - | - | ||
| 20 | 2022-01-23 | Tennessee (33) | 63 | 55 | Georgia (30) | Final | W | 8 |
| 21 | 2022-01-27 | Tennessee (33) | 61 | 71 | Auburn (81) | Final | L | -10 |
| 22 | 2022-01-31 | Arkansas (114) | 83 | 86 | Tennessee (33) | Final/OT | W | 3 |
| 23 | 2022-02-03 | Tennessee (4) | 59 | 84 | Florida (41) | Final | L | -25 |
| 24 | 2022-02-06 | Tennessee (4) | 56 | 75 | Connecticut (15) | Final | L | -19 |
| 25 | 2022-02-10 | Missouri (71) | 62 | 76 | Tennessee (33) | Final | W | 14 |
| 26 | 2022-02-13 | Vanderbilt (83) | 52 | 66 | Tennessee (8) | Final | W | 14 |
| 27 | 2022-02-17 | Tennessee (6) | 64 | 74 | Alabama (80) | Final | L | -10 |
| 28 | 2022-02-20 | Tennessee (6) | 53 | 67 | South Carolina (1) | Final | L | -14 |
| 29 | 2022-02-24 | Mississippi State (53) | 64 | 86 | Tennessee (11) | Final | W | 22 |
| 30 | 2022-02-27 | LSU (6) | 57 | 54 | Tennessee (11) | Final | L | -3 |
| 31 | 2022-03-04 | Alabama (63) | 59 | 74 | Tennessee (12) | Final | W | 15 |
| 32 | 2022-03-05 | Kentucky (42) | 83 | 74 | Tennessee (12) | Final | L | -9 |
| 33 | 2022-03-19 | Buffalo (59) | 67 | 80 | Tennessee (10) | Final | W | 13 |
| 34 | 2022-03-21 | Belmont (73) | 67 | 70 | Tennessee (10) | Final | W | 3 |
| 35 | 2022-03-26 | Tennessee (10) | 64 | 76 | Louisville (5) | Final | L | -12 |