NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Jacksonville (323) | 69 | 66 | Minnesota (132) | Final | L | -3 |
| 2 | 2021-11-12 | Minnesota (17) | 66 | 59 | Arizona State (46) | Final/OT | W | 7 |
| 3 | 2021-11-14 | George Washington (214) | 32 | 48 | Minnesota (132) | Final | W | 16 |
| 4 | 2021-11-17 | American (130) | 56 | 73 | Minnesota (100) | Final | W | 17 |
| 5 | 2021-11-20 | Minnesota (100) | 58 | 88 | Connecticut (50) | Final | L | -30 |
| 6 | 2021-11-21 | Syracuse (113) | 63 | 70 | Minnesota (100) | Final | W | 7 |
| 7 | 2021-11-22 | Oklahoma (39) | 88 | 69 | Minnesota (100) | Final | L | -19 |
| 8 | 2021-11-26 | Bradley (155) | 54 | 73 | Minnesota (17) | Final | W | 19 |
| 9 | 2021-11-28 | UTSA (280) | 52 | 81 | Minnesota (97) | Final | W | 29 |
| 10 | 2021-12-01 | North Carolina (7) | 82 | 76 | Minnesota (82) | Final | L | -6 |
| 11 | 2021-12-06 | Nebraska (11) | 70 | 67 | Minnesota (82) | Final | L | -3 |
| 12 | 2021-12-12 | Minnesota (72) | 61 | 73 | Michigan (24) | Final | L | -12 |
| 13 | 2021-12-15 | Ohio (128) | 93 | 99 | Minnesota (78) | Final | W | 6 |
| 14 | 2021-12-23 | Minnesota (68) | 63 | 77 | Drake (63) | Final | L | -14 |
| 15 | 2021-12-31 | Northwestern (142) | 0 | 0 | Minnesota (17) | Postponed | - | - |
| 16 | 2022-01-06 | Minnesota (85) | 62 | 49 | Rutgers (136) | Final | W | 13 |
| 17 | 2022-01-09 | Maryland (18) | 87 | 73 | Minnesota (17) | Final | L | -14 |
| 18 | 2022-01-12 | Minnesota (17) | 82 | 66 | Wisconsin (77) | Final | W | 16 |
| 19 | 2022-01-15 | Ohio State (33) | 83 | 75 | Minnesota (86) | Final | L | -8 |
| 20 | 2022-01-20 | Iowa (29) | 105 | 49 | Minnesota (96) | Final | L | -56 |
| 21 | 2022-01-23 | Minnesota (17) | 71 | 74 | Michigan State (19) | Final | L | -3 |
| 22 | 2022-01-27 | Minnesota (17) | 66 | 80 | Purdue (84) | Final | L | -14 |
| 23 | 2022-01-30 | Wisconsin (246) | 55 | 57 | Minnesota (103) | Final | W | 2 |
| 24 | 2022-02-03 | Minnesota (101) | 70 | 80 | Indiana (11) | Final | L | -10 |
| 25 | 2022-02-06 | Michigan State (75) | 60 | 71 | Minnesota (101) | Final | W | 11 |
| 26 | 2022-02-09 | Minnesota (17) | 78 | 88 | Iowa (9) | Final | L | -10 |
| 27 | 2022-02-17 | Rutgers (172) | 79 | 61 | Minnesota (102) | Final | L | -18 |
| 28 | 2022-02-20 | Minnesota (102) | 70 | 93 | Nebraska (25) | Final | L | -23 |
| 29 | 2022-02-24 | Illinois (228) | 54 | 87 | Minnesota (110) | Final | W | 33 |
| 30 | 2022-02-27 | Minnesota (110) | 94 | 83 | Penn State (119) | Final | W | 11 |
| 31 | 2022-03-03 | Minnesota (99) | 60 | 65 | Northwestern (61) | Final | L | -5 |
| 32 | 2022-03-17 | Minnesota (101) | 73 | 65 | Green Bay (104) | Final | W | 8 |
| 33 | 2022-03-20 | Minnesota (101) | 57 | 78 | South Dakota State (53) | Final | L | -21 |