NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Ohio (87) | 69 | 105 | Notre Dame (60) | Final | L | -36 |
| 2 | 2021-11-13 | Ohio (87) | 63 | 66 | Liberty (136) | Final | L | -3 |
| 3 | 2021-11-16 | Ohio (275) | 73 | 62 | Cincinnati (77) | Final | W | 11 |
| 4 | 2021-11-20 | Mercyhurst | 46 | 90 | Ohio (275) | Final | W | 44 |
| 5 | 2021-11-29 | Florida A&M (321) | 45 | 98 | Ohio (159) | Final | W | 53 |
| 6 | 2021-12-04 | Richmond (43) | 89 | 98 | Ohio (163) | Final | W | 9 |
| 7 | 2021-12-15 | Ohio (128) | 93 | 99 | Minnesota (78) | Final | L | -6 |
| 8 | 2021-12-20 | Ohio (128) | 74 | 60 | UMass-Lowell (230) | Final | W | 14 |
| 9 | 2021-12-21 | Binghamton (306) | 67 | 76 | Ohio (112) | Final | W | 9 |
| 10 | 2021-12-29 | Ohio (111) | 0 | 0 | Miami (OH) (203) | Postponed | - | - |
| 11 | 2022-01-02 | Eastern Michigan (202) | 0 | 0 | Ohio (163) | Postponed | - | - |
| 12 | 2022-01-08 | Northern Illinois (310) | 71 | 68 | Ohio (163) | Final | L | -3 |
| 13 | 2022-01-12 | Kent State (173) | 64 | 70 | Ohio (163) | Final | W | 6 |
| 14 | 2022-01-12 | Buffalo | Ohio | Postponed | - | - | ||
| 15 | 2022-01-15 | Ohio (131) | 75 | 65 | Central Michigan (271) | Final | W | 10 |
| 16 | 2022-01-17 | Ohio (131) | 60 | 63 | Miami (OH) (191) | Final | L | -3 |
| 17 | 2022-01-22 | Bowling Green (154) | 70 | 85 | Ohio (140) | Final | W | 15 |
| 18 | 2022-01-24 | Buffalo (50) | 66 | 68 | Ohio (140) | Final | W | 2 |
| 19 | 2022-01-26 | Ohio (109) | 79 | 72 | Toledo (53) | Final | W | 7 |
| 20 | 2022-01-29 | Ohio (109) | 64 | 74 | Western Michigan (101) | Final | L | -10 |
| 21 | 2022-02-02 | Ball State (119) | 84 | 74 | Ohio (103) | Final | L | -10 |
| 22 | 2022-02-03 | Eastern Michigan (252) | 0 | 0 | Ohio (103) | TBD | - | - |
| 23 | 2022-02-06 | Ohio (103) | 70 | 80 | Northern Illinois (178) | Final | L | -10 |
| 24 | 2022-02-09 | Ohio (163) | 0 | 0 | Ball State (69) | Postponed | - | - |
| 25 | 2022-02-12 | Western Michigan (132) | 80 | 73 | Ohio (124) | Final | L | -7 |
| 26 | 2022-02-14 | Eastern Michigan (255) | 53 | 66 | Ohio (124) | Final | W | 13 |
| 27 | 2022-02-16 | Toledo (166) | 76 | 73 | Ohio (163) | Final | L | -3 |
| 28 | 2022-02-19 | Ohio (126) | 82 | 69 | Bowling Green (121) | Final | W | 13 |
| 29 | 2022-02-21 | Ohio (126) | 69 | 66 | Akron (138) | Final | W | 3 |
| 30 | 2022-02-23 | Ohio (123) | 65 | 79 | Buffalo (74) | Final | L | -14 |
| 31 | 2022-02-26 | Akron (129) | 88 | 77 | Ohio (123) | Final | L | -11 |
| 32 | 2022-03-02 | Miami (OH) (243) | 64 | 73 | Ohio (133) | Final | W | 9 |
| 33 | 2022-03-05 | Ohio (133) | 50 | 59 | Kent State (113) | Final | L | -9 |
| 34 | 2022-03-09 | Ohio (135) | 67 | 80 | Toledo (50) | Final | L | -13 |
| 35 | 2022-03-17 | Ohio (143) | 57 | 87 | South Dakota State (53) | Final | L | -30 |