NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-10 | Bucknell (35) | 48 | 71 | Ohio State (37) | Final | W | 23 |
| 2 | 2021-11-14 | Norfolk State (276) | 48 | 86 | Ohio State (37) | Final | W | 38 |
| 3 | 2021-11-17 | Bowling Green (154) | 63 | 94 | Ohio State (22) | Final | W | 31 |
| 4 | 2021-11-23 | Bellarmine (358) | 58 | 110 | Ohio State (11) | Final | W | 52 |
| 5 | 2021-11-27 | Cincinnati (220) | 50 | 86 | Ohio State (27) | Final | W | 36 |
| 6 | 2021-12-01 | Ohio State (25) | 91 | 97 | Syracuse (147) | Final | L | -6 |
| 7 | 2021-12-05 | Ohio State (25) | 70 | 53 | Purdue (83) | Final | W | 17 |
| 8 | 2021-12-07 | Mount St Mary's (318) | 50 | 94 | Ohio State (36) | Final | W | 44 |
| 9 | 2021-12-12 | Indiana (40) | 86 | 66 | Ohio State (36) | Final | L | -20 |
| 10 | 2021-12-15 | Alabama State (289) | 51 | 97 | Ohio State (37) | Final | W | 46 |
| 11 | 2021-12-19 | Ohio State (11) | 0 | 0 | UCLA (1) | Cancelled | - | - |
| 12 | 2021-12-21 | Ohio State (32) | 66 | 54 | San Diego State (156) | Final | W | 12 |
| 13 | 2021-12-31 | Ohio State (11) | 71 | 90 | Michigan (6) | Final | L | -19 |
| 14 | 2022-01-03 | Penn State (110) | 0 | 0 | Ohio State (30) | Postponed | - | - |
| 15 | 2022-01-06 | Illinois (213) | 69 | 90 | Ohio State (39) | Final | W | 21 |
| 16 | 2022-01-09 | Ohio State (11) | 74 | 61 | Northwestern (142) | Final | W | 13 |
| 17 | 2022-01-12 | Michigan State (19) | 83 | 89 | Ohio State (11) | Final | W | 6 |
| 18 | 2022-01-15 | Ohio State (33) | 83 | 75 | Minnesota (86) | Final | W | 8 |
| 19 | 2022-01-20 | Maryland (22) | 89 | 95 | Ohio State (30) | Final | W | 6 |
| 20 | 2022-01-23 | Ohio State (11) | 80 | 71 | Rutgers (158) | Final | W | 9 |
| 21 | 2022-01-27 | Michigan (6) | 77 | 58 | Ohio State (11) | Final | L | -19 |
| 22 | 2022-01-31 | Ohio State (11) | 92 | 88 | Iowa (9) | Final | W | 4 |
| 23 | 2022-02-07 | Rutgers (158) | 57 | 61 | Ohio State (11) | Final | W | 4 |
| 24 | 2022-02-10 | Nebraska (36) | 70 | 80 | Ohio State (11) | Final | W | 10 |
| 25 | 2022-02-14 | Ohio State (24) | 86 | 67 | Illinois (225) | Final | W | 19 |
| 26 | 2022-02-17 | Ohio State (21) | 72 | 77 | Maryland (17) | Final | L | -5 |
| 27 | 2022-02-20 | Wisconsin (226) | 42 | 59 | Ohio State (21) | Final | W | 17 |
| 28 | 2022-02-24 | Penn State (119) | 55 | 78 | Ohio State (28) | Final | W | 23 |
| 29 | 2022-02-27 | Ohio State (28) | 61 | 55 | Michigan State (84) | Final | W | 6 |
| 30 | 2022-03-04 | Michigan State (86) | 58 | 74 | Ohio State (25) | Final | W | 16 |
| 31 | 2022-03-05 | Indiana (20) | 70 | 62 | Ohio State (25) | Final | L | -8 |
| 32 | 2022-03-19 | Missouri State (51) | 56 | 63 | Ohio State (25) | Final | W | 7 |
| 33 | 2022-03-21 | Ohio State (25) | 79 | 64 | LSU (9) | Final | W | 15 |
| 34 | 2022-03-25 | Ohio State (25) | 63 | 66 | Texas (4) | Final | L | -3 |