NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-10 | Indiana (13) | 86 | 63 | Butler (277) | Final | W | 23 |
| 2 | 2021-11-14 | Kentucky (18) | 67 | 88 | Indiana (13) | Final | W | 21 |
| 3 | 2021-11-16 | Norfolk State (174) | 42 | 72 | Indiana (29) | Final | W | 30 |
| 4 | 2021-11-20 | Indiana (29) | 67 | 59 | Quinnipiac (148) | Final | W | 8 |
| 5 | 2021-11-25 | Stanford (56) | 69 | 66 | Indiana (53) | Final | L | -3 |
| 6 | 2021-11-27 | Indiana (21) | 53 | 51 | Miami (53) | Final | W | 2 |
| 7 | 2021-12-02 | North Carolina State (2) | 66 | 58 | Indiana (43) | Final | L | -8 |
| 8 | 2021-12-06 | Penn State (122) | 40 | 70 | Indiana (43) | Final | W | 30 |
| 9 | 2021-12-09 | Fairfield (164) | 58 | 91 | Indiana (40) | Final | W | 33 |
| 10 | 2021-12-12 | Indiana (40) | 86 | 66 | Ohio State (36) | Final | W | 20 |
| 11 | 2021-12-19 | Western Michigan (281) | 57 | 67 | Indiana (53) | Final | W | 10 |
| 12 | 2021-12-21 | Wright State (323) | 0 | 0 | Indiana (19) | Cancelled | - | - |
| 13 | 2021-12-23 | Southern Illinois (144) | 37 | 70 | Indiana (19) | Final | W | 33 |
| 14 | 2021-12-30 | Indiana (16) | 0 | 0 | Rutgers (129) | Postponed | - | - |
| 15 | 2022-01-02 | Maryland (18) | 63 | 70 | Indiana (53) | Final/OT | W | 7 |
| 16 | 2022-01-05 | Indiana (53) | 76 | 53 | Wisconsin (77) | Final | W | 23 |
| 17 | 2022-01-13 | Nebraska (36) | 65 | 72 | Indiana (53) | Final | W | 7 |
| 18 | 2022-01-16 | Indiana (53) | 73 | 68 | Purdue (84) | Final/OT | W | 5 |
| 19 | 2022-01-19 | Michigan State (19) | 0 | 0 | Indiana (53) | Postponed | - | - |
| 20 | 2022-01-23 | Indiana | Iowa | Postponed | - | - | ||
| 21 | 2022-01-27 | Illinois (29) | 0 | 0 | Indiana (53) | Postponed | - | - |
| 22 | 2022-01-31 | Indiana (53) | 50 | 65 | Michigan (6) | Final | L | -15 |
| 23 | 2022-02-03 | Minnesota (101) | 70 | 80 | Indiana (11) | Final | W | 10 |
| 24 | 2022-02-06 | Purdue (57) | 57 | 64 | Indiana (11) | Final | W | 7 |
| 25 | 2022-02-09 | Indiana (53) | 93 | 61 | Illinois (29) | Final | W | 32 |
| 26 | 2022-02-12 | Michigan State (81) | 58 | 76 | Indiana (11) | Final | W | 18 |
| 27 | 2022-02-14 | Indiana (11) | 55 | 72 | Nebraska (26) | Final | L | -17 |
| 28 | 2022-02-17 | Northwestern (59) | 58 | 69 | Indiana (15) | Final | W | 11 |
| 29 | 2022-02-19 | Iowa (31) | 96 | 91 | Indiana (15) | Final | L | -5 |
| 30 | 2022-02-21 | Indiana (15) | 82 | 88 | Iowa (31) | Final | L | -6 |
| 31 | 2022-02-25 | Indiana (53) | 64 | 67 | Maryland (18) | Final | L | -3 |
| 32 | 2022-03-03 | Rutgers (160) | 54 | 66 | Indiana (20) | Final | W | 12 |
| 33 | 2022-03-04 | Indiana (20) | 62 | 51 | Maryland (15) | Final | W | 11 |
| 34 | 2022-03-05 | Indiana (20) | 70 | 62 | Ohio State (25) | Final | W | 8 |
| 35 | 2022-03-06 | Indiana (20) | 67 | 74 | Iowa (19) | Final | L | -7 |
| 36 | 2022-03-19 | Charlotte (80) | 51 | 85 | Indiana (18) | Final | W | 34 |
| 37 | 2022-03-21 | Princeton (24) | 55 | 56 | Indiana (18) | Final | W | 1 |
| 38 | 2022-03-26 | Indiana (18) | 58 | 75 | Connecticut (7) | Final | L | -17 |