NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | North Carolina A&T (100) | 47 | 92 | North Carolina (41) | Final | W | 45 |
| 2 | 2021-11-14 | North Carolina (41) | 89 | 33 | Charlotte (126) | Final | W | 56 |
| 3 | 2021-11-17 | Appalachian State (184) | 44 | 89 | North Carolina (17) | Final | W | 45 |
| 4 | 2021-11-21 | North Carolina (17) | 79 | 46 | TCU (85) | Final | W | 33 |
| 5 | 2021-11-26 | North Carolina (14) | 72 | 59 | Virginia Commonwealth (235) | Final | W | 13 |
| 6 | 2021-11-27 | Washington (78) | 37 | 58 | North Carolina (9) | Final | W | 21 |
| 7 | 2021-12-01 | North Carolina (7) | 82 | 76 | Minnesota (82) | Final | W | 6 |
| 8 | 2021-12-05 | James Madison (182) | 47 | 93 | North Carolina (7) | Final | W | 46 |
| 9 | 2021-12-12 | UNC-Asheville (251) | 46 | 107 | North Carolina (4) | Final | W | 61 |
| 10 | 2021-12-15 | Jacksonville (210) | 0 | 0 | North Carolina (4) | Cancelled | - | - |
| 11 | 2021-12-19 | North Carolina (14) | 76 | 73 | Boston College (259) | Final | W | 3 |
| 12 | 2021-12-21 | Alabama State (282) | 47 | 83 | North Carolina (4) | Final | W | 36 |
| 13 | 2021-12-30 | Syracuse (68) | 43 | 79 | North Carolina (5) | Final | W | 36 |
| 14 | 2022-01-02 | Clemson (47) | 62 | 81 | North Carolina (14) | Final | W | 19 |
| 15 | 2022-01-06 | North Carolina (5) | 45 | 72 | North Carolina State (2) | Final | L | -27 |
| 16 | 2022-01-09 | Virginia Tech (39) | 46 | 71 | North Carolina (14) | Final | W | 25 |
| 17 | 2022-01-16 | North Carolina (14) | 65 | 70 | Notre Dame (20) | Final | L | -5 |
| 18 | 2022-01-20 | Virginia (200) | 52 | 61 | North Carolina (10) | Final | W | 9 |
| 19 | 2022-01-23 | North Carolina (14) | 38 | 55 | Georgia Tech (93) | Final | L | -17 |
| 20 | 2022-01-27 | North Carolina (14) | 78 | 62 | Duke (8) | Final | W | 16 |
| 21 | 2022-01-30 | North Carolina State (2) | 66 | 58 | North Carolina (16) | Final | L | -8 |
| 22 | 2022-02-03 | North Carolina (13) | 78 | 59 | Wake Forest (88) | Final | W | 19 |
| 23 | 2022-02-06 | Miami (64) | 38 | 85 | North Carolina (13) | Final | W | 47 |
| 24 | 2022-02-10 | Pittsburgh (279) | 54 | 64 | North Carolina (14) | Final | W | 10 |
| 25 | 2022-02-13 | North Carolina (12) | 61 | 66 | Virginia Tech (31) | Final | L | -5 |
| 26 | 2022-02-17 | Louisville (4) | 65 | 66 | North Carolina (14) | Final | W | 1 |
| 27 | 2022-02-20 | North Carolina (14) | 64 | 49 | Florida State (72) | Final | W | 15 |
| 28 | 2022-02-24 | North Carolina (9) | 68 | 57 | Virginia (193) | Final | W | 11 |
| 29 | 2022-02-27 | Duke (43) | 46 | 74 | North Carolina (9) | Final | W | 28 |
| 30 | 2022-03-04 | Virginia Tech (22) | 87 | 80 | North Carolina (10) | Final/OT | L | -7 |
| 31 | 2022-03-19 | Stephen F. Austin (49) | 66 | 79 | North Carolina (11) | Final | W | 13 |
| 32 | 2022-03-21 | North Carolina (11) | 63 | 45 | Arizona (26) | Final | W | 18 |
| 33 | 2022-03-25 | North Carolina (11) | 61 | 69 | South Carolina (1) | Final | L | -8 |