NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Presbyterian (252) | 53 | 81 | Kentucky (18) | Final | L | -28 |
| 2 | 2021-11-12 | Presbyterian (357) | 39 | 68 | Furman (198) | Final | L | -29 |
| 3 | 2021-11-16 | Presbyterian (340) | 51 | 52 | Western Carolina (276) | Final | L | -1 |
| 4 | 2021-11-20 | St. Thomas (351) | 62 | 82 | Presbyterian (340) | Final | W | 20 |
| 5 | 2021-11-23 | East Tennessee State (212) | 55 | 63 | Presbyterian (357) | Final | W | 8 |
| 6 | 2021-11-27 | Presbyterian (288) | 62 | 54 | Jacksonville (144) | Final | W | 8 |
| 7 | 2021-12-01 | UNC-Greensboro (237) | 53 | 60 | Presbyterian (238) | Final | W | 7 |
| 8 | 2021-12-05 | Presbyterian (238) | 42 | 48 | Clemson (72) | Final | L | -6 |
| 9 | 2021-12-15 | Piedmont | 64 | 86 | Presbyterian (249) | Final | W | 22 |
| 10 | 2021-12-18 | Presbyterian (357) | 57 | 81 | Vanderbilt (7) | Final | L | -24 |
| 11 | 2021-12-20 | Agnes Scott | 0 | 0 | Presbyterian (249) | Postponed | - | - |
| 12 | 2022-01-01 | Longwood (244) | 83 | 78 | Presbyterian (265) | Final | L | -5 |
| 13 | 2022-01-04 | Presbyterian (268) | 43 | 66 | Hampton (234) | Final | L | -23 |
| 14 | 2022-01-08 | Presbyterian (357) | 0 | 0 | North Carolina A&T (264) | Postponed | - | - |
| 15 | 2022-01-12 | Charleston Southern (317) | 58 | 68 | Presbyterian (357) | Final | W | 10 |
| 16 | 2022-01-15 | Radford (303) | 63 | 74 | Presbyterian (284) | Final | W | 11 |
| 17 | 2022-01-18 | Presbyterian (270) | 56 | 64 | Gardner-Webb (277) | Final | L | -8 |
| 18 | 2022-01-22 | Presbyterian (270) | 69 | 54 | UNC-Asheville (302) | Final | W | 15 |
| 19 | 2022-01-26 | Campbell (150) | 58 | 55 | Presbyterian (280) | Final | L | -3 |
| 20 | 2022-01-29 | High Point (238) | 57 | 47 | Presbyterian (280) | Final | L | -10 |
| 21 | 2022-02-01 | Presbyterian (291) | 42 | 58 | Winthrop (354) | Final | L | -16 |
| 22 | 2022-02-05 | Presbyterian (357) | 60 | 49 | Charleston Southern (317) | Final | W | 11 |
| 23 | 2022-02-08 | Hampton (305) | 56 | 53 | Presbyterian (357) | Final | L | -3 |
| 24 | 2022-02-10 | Presbyterian (357) | 52 | 80 | North Carolina A&T (264) | Final | L | -28 |
| 25 | 2022-02-12 | North Carolina A&T (240) | 73 | 56 | Presbyterian (304) | Final | L | -17 |
| 26 | 2022-02-15 | Presbyterian (314) | 66 | 68 | South Carolina Upstate (182) | Final | L | -2 |
| 27 | 2022-02-16 | South Carolina Upstate (315) | 80 | 67 | Presbyterian (357) | Final | L | -13 |
| 28 | 2022-02-19 | Presbyterian (314) | 63 | 76 | Longwood (214) | Final | L | -13 |
| 29 | 2022-02-22 | Gardner-Webb (242) | 58 | 72 | Presbyterian (317) | Final | W | 14 |
| 30 | 2022-02-26 | Presbyterian (317) | 61 | 57 | Radford (333) | Final | W | 4 |
| 31 | 2022-03-01 | Winthrop (350) | 60 | 65 | Presbyterian (305) | Final | W | 5 |
| 32 | 2022-03-03 | Presbyterian (305) | 56 | 59 | Campbell (168) | Final/OT | L | -3 |