NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Charleston (250) | 80 | 48 | Wofford (228) | Final | L | -32 |
| 2 | 2021-11-12 | Wofford (220) | 57 | 90 | North Carolina State (27) | Final | L | -33 |
| 3 | 2021-11-14 | Towson (131) | 64 | 48 | Wofford (228) | Final | L | -16 |
| 4 | 2021-11-15 | Wofford (228) | 47 | 61 | Florida (77) | Final | L | -14 |
| 5 | 2021-11-19 | Southern Wesleyan | 55 | 106 | Wofford (353) | Final | W | 51 |
| 6 | 2021-11-23 | UNC-Asheville (308) | 70 | 64 | Wofford (220) | Final | L | -6 |
| 7 | 2021-11-30 | High Point (163) | 52 | 74 | Wofford (311) | Final | W | 22 |
| 8 | 2021-12-04 | Wofford (220) | 46 | 58 | Coastal Carolina (178) | Final | L | -12 |
| 9 | 2021-12-08 | Brevard | 37 | 101 | Wofford (272) | Final | W | 64 |
| 10 | 2021-12-12 | Wofford (272) | 78 | 65 | Appalachian State (142) | Final | W | 13 |
| 11 | 2021-12-17 | Wofford (209) | 49 | 84 | Clemson (117) | Final | L | -35 |
| 12 | 2021-12-20 | Northern Kentucky (145) | 84 | 64 | Wofford (209) | Final | L | -20 |
| 13 | 2021-12-30 | Wofford (264) | 62 | 72 | Tulane (96) | Final | L | -10 |
| 14 | 2022-01-01 | Erskine | 26 | 72 | Wofford (264) | Final | W | 46 |
| 15 | 2022-01-06 | Western Carolina (315) | 48 | 72 | Wofford (266) | Final | W | 24 |
| 16 | 2022-01-08 | UNC-Greensboro (254) | 0 | 0 | Wofford (220) | Postponed | - | - |
| 17 | 2022-01-13 | Wofford (220) | 74 | 69 | Furman (198) | Final | W | 5 |
| 18 | 2022-01-20 | Wofford (236) | 80 | 69 | Samford (261) | Final | W | 11 |
| 19 | 2022-01-22 | Wofford (236) | 53 | 67 | Mercer (117) | Final | L | -14 |
| 20 | 2022-01-27 | Chattanooga (187) | 53 | 76 | Wofford (220) | Final | W | 23 |
| 21 | 2022-01-29 | East Tennessee State (336) | 51 | 73 | Wofford (229) | Final | W | 22 |
| 22 | 2022-02-03 | Wofford (222) | 63 | 45 | UNC-Greensboro (307) | Final | W | 18 |
| 23 | 2022-02-05 | Wofford (220) | 71 | 49 | Western Carolina (353) | Final | W | 22 |
| 24 | 2022-02-12 | Furman (252) | 54 | 72 | Wofford (213) | Final | W | 18 |
| 25 | 2022-02-17 | Mercer (116) | 74 | 57 | Wofford (199) | Final | L | -17 |
| 26 | 2022-02-19 | Samford (261) | 52 | 60 | Wofford (199) | Final | W | 8 |
| 27 | 2022-02-21 | UNC-Greensboro (319) | 47 | 55 | Wofford (199) | Final | W | 8 |
| 28 | 2022-02-24 | Wofford (202) | 64 | 70 | East Tennessee State (331) | Final | L | -6 |
| 29 | 2022-02-26 | Wofford (202) | 84 | 75 | Chattanooga (313) | Final | W | 9 |
| 30 | 2022-03-03 | East Tennessee State (327) | 54 | 66 | Wofford (209) | Final | W | 12 |
| 31 | 2022-03-04 | Furman (238) | 64 | 59 | Wofford (209) | Final | L | -5 |
| 32 | 2022-03-17 | Wofford (213) | 56 | 86 | Middle Tennessee (71) | Final | L | -30 |